Patents by Inventor Alexander Kover

Alexander Kover has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused heterocyclic compounds as inhibitors of potassium channel function
    Patent number: 8357704
    Abstract: A compound of formula I wherein m, n, A, B, D, E, G, H, Y, R1, R2, R3, R4, R5, and R8, are described herein.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: January 22, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: James A. Johnson, John Lloyd, Alexander Kover
  • FUSED HETEROCYCLIC COMPOUNDS AS INHIBITORS OF POTASSIUM CHANNEL FUNCTION
    Publication number: 20100247534
    Abstract: A compound of formula I wherein m, n, A, B, D, E, G, H, Y, R1, R2, R3, R4, R5, and R8, are described herein.
    Type: Application
    Filed: June 10, 2010
    Publication date: September 30, 2010
    Inventors: James A. Johnson, John Lloyd, Alexander Kover
  • Fused heterocyclic compounds
    Publication number: 20050250783
    Abstract: A compound of formula I wherein m, n, A, B, D, E, G, H, Y, R1, R2, R3, R4, R5, and R8, are described herein.
    Type: Application
    Filed: April 13, 2005
    Publication date: November 10, 2005
    Inventors: James Johnson, John Lloyd, Alexander Kover
  • Spiro-isoxazolidine derivatives as cholinergic agents
    Patent number: 5073560
    Abstract: Compounds of general formula I, ##STR1## wherein: A represents (CH.sub.2).sub.m optionally substituted by R.sub.3,B represents (CH.sub.2).sub.n optionally substituted by R.sub.4,R.sub.1 represents hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1-6 alkenyl or C.sub.1-6 alkynyl,R.sub.2 represents hydrogen, C.sub.1 -C.sub.6 alkyl or COOR.sub.5, in which R.sub.5 represents C.sub.1 -C.sub.6 alkyl,R.sub.3 and R.sub.4 independently represent hydrogen or C.sub.1 -C.sub.6 alkyl,in addition, any two of R.sub.2, R.sub.3 and R.sub.4 may together form a C.sub.1-3 alkylene chain,n and m independently represent an integer from 1-3 inclusive,Y represents O or S,and pharmaceutically acceptable acid addition salts thereof are useful as pharmaceuticals, in particular as central muscarinic acetylcholine receptor agonists. The compounds are therefore useful in the treatment of diseases such as presenile and senile dementia, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania and Tourette Syndrome.
    Type: Grant
    Filed: July 20, 1990
    Date of Patent: December 17, 1991
    Assignee: Fisons Corporation
    Inventors: Edwin S. Wu, Alexander Kover
  • Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase
    Patent number: 4889941
    Abstract: 7-[3-[(3,4-dihydroxyphenethyl)amino]-2-hydroxypropoxy]-flavone hydrobromide, and related flavonoids are disclosed to inhibit leukotrienes and 5-lipoxygenase; preferred compounds also inhibit rat anaphylaxis.
    Type: Grant
    Filed: December 4, 1987
    Date of Patent: December 26, 1989
    Assignee: Fisons Corporation
    Inventors: Edwin S. Wu, Alexander Kover