Patents by Inventor Alexander Miron

Alexander Miron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR IMPROVED MULTIPLEX GENOTYPING AND SEQUENCING
    Publication number: 20220310203
    Abstract: The technology described herein is directed to methods of designing primers for multiplex PCR amplification. Also described herein are methods for equalization of reads in these approaches. A variation is described herein that permits single base multiplexed sequencing on an NGS platform. Also described herein are methods to rapidly analyze NGS sequencing data to automatically provide genotype or sequencing results and methods to identify and quantify low abundance rare variants in clinically relevant genes in a minority of tumor cells from a complex mixture of cells.
    Type: Application
    Filed: June 28, 2019
    Publication date: September 29, 2022
    Applicant: COVARIANCE BIOSCIENCES, LLC
    Inventor: Alexander MIRON
  • Exon grouping analysis
    Patent number: 8906620
    Abstract: This invention pertains to the identification of specific disease-causing DNA sequences in a subject. The methods of the present invention can be used to identify genetic alterations, to determine the molecular basis for genetic diseases, and to provide carrier and prenatal diagnosis for genetic counseling.
    Type: Grant
    Filed: March 24, 2008
    Date of Patent: December 9, 2014
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Alexander Miron, J. Dirk Iglehart
  • Fibrinogen alpha and hemoglobin polypeptides as cancer markers
    Patent number: 8318441
    Abstract: The present invention provides methods of detecting cancer using biomarkers.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: November 27, 2012
    Assignee: Dana-Farber Cancer Institute, Inc.
    Inventors: Alexander Miron, James Dirk Iglehart, Lyndsay N. Harris, Xin Lu, Qian Shi
  • Fibrinogen Alpha and Hemoglobin Polypeptides as Cancer Markers
    Publication number: 20100248271
    Abstract: The present invention provides methods of detecting cancer using biomarkers.
    Type: Application
    Filed: April 2, 2010
    Publication date: September 30, 2010
    Inventors: Alexander Miron, James D. Iglehart, Lyndsay N. Harris, Xin Lu, Qian Shi
  • Exon grouping analysis
    Publication number: 20090191547
    Abstract: This invention pertains to the identification of specific disease-causing DNA sequences in a subject. The methods of the present invention can be used to identify genetic alterations, to determine the molecular basis for genetic diseases, and to provide carrier and prenatal diagnosis for genetic counseling.
    Type: Application
    Filed: March 24, 2008
    Publication date: July 30, 2009
    Inventors: Alexander Miron, J. Dirk Iglehart