Patents by Inventor Alexander Perov
Alexander Perov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230349897Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: July 10, 2023Publication date: November 2, 2023Inventors: Christopher G. COONEY, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Patent number: 11747332Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: GrantFiled: November 24, 2020Date of Patent: September 5, 2023Assignee: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
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Publication number: 20210215689Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: November 24, 2020Publication date: July 15, 2021Inventors: Christopher G. COONEY, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Patent number: 10877028Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: GrantFiled: September 13, 2019Date of Patent: December 29, 2020Assignee: Akonni Biosystems, Inc.Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
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Patent number: 10526645Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: GrantFiled: September 29, 2016Date of Patent: January 7, 2020Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
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Publication number: 20200002755Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: September 13, 2019Publication date: January 2, 2020Inventors: Christopher G. Cooney, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Publication number: 20190178903Abstract: A positioning system for a sample analysis device is disclosed. The positioning system comprises (1) a carousel comprising a platform and a sample loading tray mounted on the platform, and (2) a stage comprising a positioning system for positioning the carousel under the optical path of an imaging system. The sample loading tray is configured for holding a cartridge comprising one or more lateral flow cells (LFCs).Type: ApplicationFiled: February 12, 2019Publication date: June 13, 2019Inventors: Christopher COONEY, Alexander Perov, Arial Bueno, Charles Daitch
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Publication number: 20170336429Abstract: A positioning system for a sample analysis device is disclosed. The positioning system comprises (1) a carousel comprising a platform and a sample loading tray mounted on the platform, and (2) a stage comprising a positioning system for positioning the carousel under the optical path of an imaging system. The sample loading tray is configured for holding a cartridge comprising one or more lateral flow cells (LFCs).Type: ApplicationFiled: August 2, 2017Publication date: November 23, 2017Inventors: Christopher COONEY, Alexander PEROV, AriaI BUENO, Charles DAITCH
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Patent number: 9753047Abstract: A positioning system for a sample analysis device is disclosed. The positioning system comprises (1) a carousel comprising a platform and a sample loading tray mounted on the platform, and (2) a stage comprising a positioning system for positioning the carousel under the optical path of an imaging system. The sample loading tray is configured for holding a cartridge comprising one or more lateral flow cells (LFCs).Type: GrantFiled: October 26, 2015Date of Patent: September 5, 2017Assignee: AKONNI BIOSYSTEMS INC.Inventors: Christopher Cooney, Alexander Perov, Arial Bueno, Charles Daitch
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Publication number: 20170016052Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: September 29, 2016Publication date: January 19, 2017Inventors: Christopher G. COONEY, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Patent number: 9493815Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: GrantFiled: June 3, 2014Date of Patent: November 15, 2016Assignee: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. Cooney, Peter Qiang Qu, Alexander Perov, Jennifer Parker
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Publication number: 20160116495Abstract: A positioning system for a sample analysis device is disclosed. The positioning system comprises (1) a carousel comprising a platform and a sample loading tray mounted on the platform, and (2) a stage comprising a positioning system for positioning the carousel under the optical path of an imaging system. The sample loading tray is configured for holding a cartridge comprising one or more lateral flow cells (LFCs).Type: ApplicationFiled: October 26, 2015Publication date: April 28, 2016Inventors: CHRISTOPHER COONEY, Alexander Perov, Arial Bueno, Charles Daitch
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Publication number: 20140287954Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: June 3, 2014Publication date: September 25, 2014Applicant: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. COONEY, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Publication number: 20120196767Abstract: A microarray assembly for detection of a target molecule is disclosed. The microarray assemblies comprise an array chamber having a microarray located therein and features that facilitate liquid movement within the array chamber. Also disclosed are methods for making the microarray assembly using rollable films and methods for detecting microarray spots using an internal control fluorophore in the array spot.Type: ApplicationFiled: April 13, 2012Publication date: August 2, 2012Applicant: AKONNI BIOSYSTEMS, INC.Inventors: Christopher G. COONEY, Peter Qiang QU, Alexander PEROV, Jennifer PARKER
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Patent number: 7829644Abstract: New gel-forming reagents including monomers and cross-linkers, which can be applied to gel-drop microarray manufacturing by using co-polymerization approaches are disclosed. Compositions for the preparation of co-polymerization mixtures with new gel-forming monomers and cross-linker reagents are described herein. New co-polymerization compositions and cross-linkers with variable length linker groups between unsaturated C?C bonds that participate in the formation of gel networks are disclosed.Type: GrantFiled: October 18, 2006Date of Patent: November 9, 2010Assignee: UChicago Argonne, LLCInventors: Julia Golova, Boris Chernov, Alexander Perov
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Publication number: 20070249797Abstract: New gel-forming reagents including monomers and cross-linkers, which can be applied to gel-drop microarray manufacturing by using co-polymerization approaches are disclosed. Compositions for the preparation of co-polymerization mixtures with new gel-forming monomers and cross-linker reagents are described herein. New co-polymerization compositions and cross-linkers with variable length linker groups between unsaturated C?C bonds that participate in the formation of gel networks are disclosed.Type: ApplicationFiled: October 18, 2006Publication date: October 25, 2007Applicant: UChicago Argonne LLCInventors: Julia Golova, Boris Chernov, Alexander Perov
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Publication number: 20070072213Abstract: A method and apparatus are provided for implementing non-destructive quality control of substrates and printed biological microarrays. A method and apparatus are provided for implementing quality control of gel-based microarrays prepared by dispensing a gel-forming composition on a solid substrate. The method utilizes the difference between the wettability properties of a supporting substrate and a gel, where the gel is hydrophilic. Condensation of vapor of a chemically inert water-soluble liquid, such as water or glycerol, on the surface of a substrate under inspection creates a layer of tiny droplets that affect both transmission and scattering of light on the surface. A pattern of condensation, characterized by spatial distribution, average size of the droplets and spacing between the droplets, reflects variation in wetting properties of the substrate. The pattern of condensation circumscribes printed microarray features to be non-destructively imaged and analyzed.Type: ApplicationFiled: July 12, 2006Publication date: March 29, 2007Inventors: Alexander Perov, Darrell Chandler
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Patent number: 6407395Abstract: A portable biochip scanner device used to detect and acquire fluorescence signal data from biological microchips (biochips) is provided. The portable biochip scanner device employs a laser for emitting an excitation beam. An optical fiber delivers the laser beam to a portable biochip scanner. A lens collimates the laser beam, the collimated laser beam is deflected by a dichroic mirror and focused by an objective lens onto a biochip. The fluorescence light from the biochip is collected and collimated by the objective lens. The fluorescence light is delivered to a photomultiplier tube (PMT) via an emission filter and a focusing lens. The focusing lens focuses the fluorescence light into a pinhole. A signal output of the PMT is processed and displayed.Type: GrantFiled: February 29, 2000Date of Patent: June 18, 2002Assignee: The University of ChicagoInventors: Alexander Perov, Alexei Sharonov, Andrei D. Mirzabekov
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Patent number: 6329661Abstract: A biochip scanner device used to detect and acquire fluorescence signal data from biological microchips or biochips and method of use are provided. The biochip scanner device includes a laser for emitting a laser beam. A modulator, such as an optical chopper modulates the laser beam. A scanning head receives the modulated laser beam and a scanning mechanics coupled to the scanning head moves the scanning head relative to the biochip. An optical fiber delivers the modulated laser beam to the scanning head. The scanning head collects the fluorescence light from the biochip, launches it into the same optical fiber, which delivers the fluorescence into a photodetector, such as a photodiode. The biochip scanner device is used in a row scanning method to scan selected rows of the biochip with the laser beam size matching the size of the immobilization site.Type: GrantFiled: February 29, 2000Date of Patent: December 11, 2001Assignee: The University of ChicagoInventors: Alexander Perov, Alexander I. Belgovskiy, Andrei D. Mirzabekov