Patents by Inventor Alexandr Jegorov

Alexandr Jegorov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline polymorphs of Rigosertib Sodium
    Patent number: 11981624
    Abstract: The present disclosure encompasses crystalline polymorphs of Rigosertib Sodium, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: May 14, 2024
    Inventors: Pavel Kolesa, Roman Gabriel, Alexandr Jegorov
  • SOLID STATE FORM OF LEMBOREXANT
    Publication number: 20240010629
    Abstract: The present disclosure encompasses Lemborexant: succinic acid, a solid state form thereof, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: December 10, 2020
    Publication date: January 11, 2024
    Inventors: Zuzana Trcková, Adéla Bártová, Pavel Kolesa, Alexandr Jegorov
  • SOLID STATE FORMS OF LORECIVIVINT
    Publication number: 20230373998
    Abstract: The present disclosure encompasses solid state forms of Lorecivivint, in embodiments crystalline polymorphs of Lorecivivint, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: October 12, 2021
    Publication date: November 23, 2023
    Applicant: TEVA CZECH INDUSTRIES S.R.O
    Inventors: Zuzana Przeczkova, Adéla Bártová, Pavel Kolesa, Alexandr Jegorov
  • SOLID STATE FORMS OF VOCLOSPORIN
    Publication number: 20230167156
    Abstract: The present disclosure relates to solid state forms of Voclosporin and salts thereof, processes for preparation thereof and pharmaceutical compositions thereof.
    Type: Application
    Filed: January 23, 2023
    Publication date: June 1, 2023
    Inventors: Pavel Kolesa, Ladislav Cvak, Alexandr Jegorov, Katerina Ondruszova
  • Solid state forms of voclosporin
    Patent number: 11584779
    Abstract: The present disclosure relates to solid state forms of Voclosporin processes for preparation thereof, pharmaceutical compositions thereof and uses thereof for treating lupus nephritis.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: February 21, 2023
    Inventors: Pavel Kolesa, Ladislav Cvak, Alexandr Jegorov, Katerina Ondruszova
  • SOLID STATE FORMS OF RELUGOLIX
    Publication number: 20220227784
    Abstract: The present disclosure provides solid state forms of Relugolix, crystalline forms of Relugolix, pharmaceutical compositions thereof, and pharmaceutical formulations thereof. Methods for producing these forms of Relugolix, pharmaceutical compositions, and pharmaceutical formulations are also provided.
    Type: Application
    Filed: April 6, 2022
    Publication date: July 21, 2022
    Inventors: Hana Kantor, Roman Gabriel, Pavel Kolesa, Alexandr Jegorov
  • Solid state forms of Relugolix
    Patent number: 11306104
    Abstract: The present disclosure provides solid state forms of Relugolix, crystalline forms of Relugolix, pharmaceutical compositions thereof, and pharmaceutical formulations thereof. Methods for producing these forms of Relugolix, pharmaceutical compositions, and pharmaceutical formulations are also provided.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: April 19, 2022
    Assignee: TEVA PHARMACEUTICALS INTERNATIONAL GMBH
    Inventors: Hana Kantor, Roman Gabriel, Pavel Kolesa, Alexandr Jegorov
  • RIBOCICLIB SALTS AND SOLID STATE FORMS THEREOF
    Publication number: 20220041598
    Abstract: The present disclosure relates to Ribociclib solid state forms, Ribociclib salts including Ribociclib succinate and solid state forms thereof, as well as processes for preparation thereof and pharmaceutical compositions thereof.
    Type: Application
    Filed: October 25, 2021
    Publication date: February 10, 2022
    Inventors: Helena Ceric, Elisa Vergani, Paolo S. Tiseni, Hana Kantor, Piero Paravidino, Nikolina Janton, Christian Galluzzo, Alexandr Jegorov
  • SOLID STATE FORMS OF LUMATEPERONE SALTS AND PROCESSES FOR PREPARATION OF LUMATEPERONE AND SALTS THEREOF
    Publication number: 20220024924
    Abstract: The present disclosure relates to solid state forms of Lumateperone besylate and Lumateperone tosylate:R-(?)-mandelic acid, to various intermediates, to processes for their preparation and the preparation of Lumateperone or salt thereof, to pharmaceutical compositions and their use for the treatment of central nervous system disorders.
    Type: Application
    Filed: November 27, 2019
    Publication date: January 27, 2022
    Inventors: Nikolina Janton, Helena Ceric, Sanja Matecic Musanic, Natasa Mrsic, Lidija Lerman, Tina D. Momcilovic, Ivana Sagud, Alexandr Jegorov
  • NEW CRYSTALLINE POLYMORPHS OF RIGOSERTIB SODIUM
    Publication number: 20210395193
    Abstract: The present disclosure encompasses crystalline polymorphs of Rigosertib Sodium, processes for preparation thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: October 24, 2019
    Publication date: December 23, 2021
    Inventors: Pavel Kolesa, Roman Gabriel, Alexandr Jegorov
  • SOLID STATE FORMS OF VOCLOSPORIN
    Publication number: 20210388027
    Abstract: The present disclosure relates to solid state forms of Voclosporin processes for preparation thereof, pharmaceutical compositions thereof and uses thereof for treating lupus nephritis.
    Type: Application
    Filed: October 21, 2019
    Publication date: December 16, 2021
    Inventors: Pavel Kolesa, Ladislav Cvak, Alexandr Jegorov, Katerina Ondruszova
  • Ribociclib salts and solid state forms thereof
    Patent number: 11155545
    Abstract: The present disclosure relates to Ribociclib solid state forms, Ribociclib salts including Ribociclib succinate and solid state forms thereof, as well as processes for preparation thereof and pharmaceutical compositions thereof.
    Type: Grant
    Filed: August 22, 2018
    Date of Patent: October 26, 2021
    Assignee: Sicor—Societa Italiana Corticosteroid s.r.l.
    Inventors: Helena Ceric, Elisa Vergani, Paolo S. Tiseni, Hana Kantor, Piero Paravidino, Nikolina Janton, Christian Galluzzo, Alexandr Jegorov
  • SOLID STATE FORMS OF RELUGOLIX
    Publication number: 20210017188
    Abstract: The present disclosure provides solid state forms of Relugolix, crystalline forms of Relugolix, pharmaceutical compositions thereof, and pharmaceutical formulations thereof. Methods for producing these forms of Relugolix, pharmaceutical compositions, and pharmaceutical formulations are also provided.
    Type: Application
    Filed: March 14, 2019
    Publication date: January 21, 2021
    Inventors: Hana Kantor, Roman Gabriel, Pavel Kolesa, Alexandr Jegorov
  • RIBOCICLIB SALTS AND SOLID STATE FORMS THEREOF
    Publication number: 20200190084
    Abstract: The present disclosure relates to Ribociclib solid state forms, Ribociclib salts including Ribociclib succinate and solid state forms thereof, as well as processes for preparation thereof and pharmaceutical compositions thereof.
    Type: Application
    Filed: August 22, 2018
    Publication date: June 18, 2020
    Inventors: Helena Ceric, Elisa Vergani, Paolo S. Tiseni, Hana Kantor, Piero Paravidino, Nikolina Janton, Christian Galluzzo, Alexandr Jegorov
  • SOLID STATE FORMS OF SPIRO-OXINDOLE COMPOUNDS
    Publication number: 20200109151
    Abstract: The present invention provides solid state forms of certain spiro-oxindole compounds, such as funapide and the racemic mixture of funapide and its corresponding (R) enantiomer, pharmaceutical compositions comprising the solid state forms and processes for preparing the solid state forms and the pharmaceutical compositions.
    Type: Application
    Filed: December 6, 2019
    Publication date: April 9, 2020
    Inventors: Ronen BEN-DAVID, Stephen BIERLMAIER, Ralph Curtis HALTIWANGER, Alexandr JEGOROV, Raeann Ruiyun WU, Mehran YAZDANIAN
  • Solid state forms of spiro-oxindole compounds
    Patent number: 10513526
    Abstract: The present invention provides solid state forms of certain spiro-oxindole compounds, such as funapide and the racemic mixture of funapide and its corresponding (R) enantiomer, pharmaceutical compositions comprising the solid state forms and processes for preparing the solid state forms and the pharmaceutical compositions.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: December 24, 2019
    Assignee: Xenon Pharmaceuticals Inc.
    Inventors: Ronen Ben-David, Stephen Bierlmaier, Ralph Curtis Haltiwanger, Alexandr Jegorov, Raeann Ruiyun Wu, Mehran Yazdanian
  • SOLID STATE FORMS OF SPIRO-OXINDOLE COMPOUNDS
    Publication number: 20190071449
    Abstract: The present invention provides solid state forms of certain spiro-oxindole compounds, such as funapide and the racemic mixture of funapide and its corresponding (R) enantiomer, pharmaceutical compositions comprising the solid state forms and processes for preparing the solid state forms and the pharmaceutical compositions.
    Type: Application
    Filed: October 10, 2018
    Publication date: March 7, 2019
    Inventors: Ronen Ben-David, Stephen Bierlmaier, Ralph Curtis Haltiwanger, Alexandr Jegorov, Raeann Ruiyun Wu, Mehran Yazdanian
  • Solid state forms of spiro-oxindole compounds
    Patent number: 10118932
    Abstract: The present invention provides solid state forms of certain spiro-oxindole compounds, such as funapide and the racemic mixture of funapide and its corresponding (R) enantiomer, pharmaceutical compositions comprising the solid state forms and processes for preparing the solid state forms and the pharmaceutical compositions.
    Type: Grant
    Filed: June 16, 2017
    Date of Patent: November 6, 2018
    Assignee: Xenon Pharmaceuticals Inc.
    Inventors: Ronen Ben-David, Stephen Bierlmaier, Ralph Curtis Haltiwanger, Alexandr Jegorov, Raeann Ruiyun Wu, Mehran Yazdanian
  • SOLID STATE FORMS OF SPIRO-OXINDOLE COMPOUNDS
    Publication number: 20180016283
    Abstract: The present invention provides solid state forms of certain spiro-oxindole compounds, such as funapide and the racemic mixture of funapide and its corresponding (R) enantiomer, pharmaceutical compositions comprising the solid state forms and processes for preparing the solid state forms and the pharmaceutical compositions.
    Type: Application
    Filed: June 16, 2017
    Publication date: January 18, 2018
    Inventors: Ronen Ben-David, Stephen Bierlmaier, Ralph Curtis Haltiwanger, Alexandr Jegorov, Raeann Ruiyun Wu, Mehran Yazdanian
  • SOLID STATE FORMS OF CRISABOROLE
    Publication number: 20170305936
    Abstract: Solid state forms of Crisaborole and salts thereof, processes for preparation thereof and pharmaceutical compositions thereof are disclosed.
    Type: Application
    Filed: July 12, 2017
    Publication date: October 26, 2017
    Inventors: Helena Ceric, Marica Malenica, Marina Ratkaj, Ivana Landeka, Alexandr Jegorov