Patents by Inventor Alexandre Haefele

Alexandre Haefele has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescent boron-substituted dipyrromethenes and use thereof for diagnosis
    Patent number: 8993781
    Abstract: The invention relates to novel fluorescent compounds derived from non-fluorinated dipyrromethene-boron, to a method for preparing same and to the use thereof for the fluorescent marking of biological molecules. The invention also relates to biological molecules marked with said fluorescent compounds, and to the use thereof in detection methods such as medical diagnosis methods. More particularly, the detection methods of the invention are particularly useful for diagnosing neurodegenerative diseases such as Alzheimer's disease.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: March 31, 2015
    Assignees: Centre National de la Recherche Scientifique, Universite de Strasbourg
    Inventors: Jean De Barry, Corinne Liegeois, Alexandre Haefele, Thomas Bura, Gilles Ulrich, Raymond Ziessel
  • Dipyrromethene-boron hydrophilic fluorescent compounds
    Patent number: 8476461
    Abstract: Dipyrromethene-boron hydrophilic fluorescent compounds The invention concerns fluorescent and hydrophilic compounds meeting following formula (I): wherein: S1 is a group of formula —C?C-L?-A where L? is a linkage group and A is a polar functional group; S2 is a —C?C-L?-A group the same or different from S1; —F; —H; or a hydrocarbon chain optionally interrupted by one or more oxygen atoms, and use thereof, in particular in aqueous or hydrophilic media.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: July 2, 2013
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Gilles Ulrich, Raymond Ziessel, Song-Lin Niu, Alexandre Haefele, Thomas Bura
  • DIPYRROMETHENE-BORON HYDROPHILIC FLUORESCENT COMPOUNDS
    Publication number: 20120009615
    Abstract: Dipyrromethene-boron hydrophilic fluorescent compounds The invention concerns fluorescent and hydrophilic compounds meeting following formula (I): wherein: S1 is a group of formula —C?C-L?-A where L? is a linkage group and A is a polar functional group; S2 is a —C?C-L?-A group the same or different from S1; —F; —H; or a hydrocarbon chain optionally interrupted by one or more oxygen atoms, and use thereof, in particular in aqueous or hydrophilic media.
    Type: Application
    Filed: December 18, 2009
    Publication date: January 12, 2012
    Inventors: Gilles Ulrich, Raymond Ziessel, Song-Lin Niu, Alexandre Haefele, Thomas Bura
  • Novel Fluorescent Boron-Substituted Dipyrromethenes and Use Thereof for Diagnosis
    Publication number: 20110287473
    Abstract: The invention relates to novel fluorescent compounds derived from non-fluorinated dipyrromethene-boron, to a method for preparing same and to the use thereof for the fluorescent marking of biological molecules. The invention also relates to biological molecules marked with said fluorescent compounds, and to the use thereof in detection methods such as medical diagnosis methods. More particularly, the detection methods of the invention are particularly useful for diagnosing neurodegenerative diseases such as Alzheimer's disease.
    Type: Application
    Filed: December 28, 2009
    Publication date: November 24, 2011
    Inventors: Jean De Barry, Corinne Liegeois, Alexandre Haefele, Thomas Bura, Gilles Ulrich, Raymond Ziessel