Abstract: The disclosure provides methods of preparing pouched products which includes the production of an agglomerated composition situated with a cavity of an outer water-permeable pouch. The pouched agglomerate can be dosed with a given amount of moisture, resulting in at least partial degradation and/or expansion of the agglomerated composition into powdered form. Pouched products prepared according to such methods are also described.

Abstract: The disclosure provides compositions configured for oral use, the compositions including at least one filler, water, a basic amine, and an organic acid, an alkali metal salt of an organic acid, or a combination thereof, wherein the organic acid has a log P value of from about 1.4 to about 8.0. At least a portion of the basic amine is associated with at least a portion of the organic acid or the alkali metal salt thereof. The association is in the form of a basic amine-organic acid salt, an ion pair between the basic amine and a conjugate base of the organic acid, or a combination of both. Further provided are methods for stabilizing a composition configured for oral use, for enhancing a predicted buccal absorption of a composition configured for oral use, and for reducing potential throat irritation associated with the use of compositions including a basic amine.

Abstract: A composition enclosed in a pouch to form a pouched product configured for oral use is provided, the composition including a filler in an amount of at least 20% by weight, based on the total weight of the composition, and at least one active ingredient, at least one flavorant, or a combination thereof. The composition is loaded within the pouch at a density of about 0.45 g/cm3 or higher. Further provided are methods of preparing the pouched product.

Abstract: The disclosure provides compositions adapted for oral use and, in particular, multi-compartment oral pouched products including such compositions. Some aspects of the disclosure relate to oral pouched products including a composition adapted for oral use within a porous pouch. In particular, the porous pouch may include two or more compartments, each compartment having a content of the composition contained therein. The composition within each compartment can be different such that the composition within each compartment provides a different functional or sensory experience, such as through use of a different flavoring agent, a different active ingredient, or both a different flavoring agent and a different active ingredient.