Patents by Inventor ALEXANDRE ORTHWEIN

ALEXANDRE ORTHWEIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Homologous recombination factors
    Patent number: 11261466
    Abstract: The invention relates to factors that influence or regulate homologous recombination, methods to monitor these factors, the use of these factors to screen for agents that modulate homologous recombination, and methods to activate or modulate homologous recombination.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: March 1, 2022
    Assignee: Sinai Health System
    Inventors: Daniel Durocher, Alexandre Orthwein, Sylvie Noordermeer
  • HOMOLOGOUS RECOMBINATION FACTORS
    Publication number: 20180073039
    Abstract: The invention relates to factors that influence or regulate homologous recombination, methods to monitor these factors, the use of these factors to screen for agents that modulate homologous recombination, and methods to activate or modulate homologous recombination.
    Type: Application
    Filed: March 1, 2016
    Publication date: March 15, 2018
    Inventors: Daniel Durocher, Alexandre Orthwein, Sylvie Noordermeer
  • MODULATING AND/OR DETECTING ACTIVATION INDUCED DEAMINASE AND METHODS OF USE THEREOF
    Publication number: 20110237560
    Abstract: A method for stratifying a subject, said method comprising: measuring the AID expression and/or activity in a first sample of the subject, and comparing said expression and/or activity to a reference AID expression and/or activity, wherein an AID expression and/or activity in the first sample of the subject that is higher than the reference AID expression and/or activity is indicative that the subject would benefit from a treatment with at least one Heat Shock Protein 90 (Hsp90) inhibitor.
    Type: Application
    Filed: March 11, 2011
    Publication date: September 29, 2011
    Inventors: JAVIER M. DI NOIA, ALEXANDRE ORTHWEIN