Patents by Inventor Alexandre Prieur

Alexandre Prieur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING ESOPHAGEAL CANCER
    Publication number: 20240085423
    Abstract: The present invention relates to methods for the in vitro diagnosis of esophageal cancer, and to compositions and methods for the prevention or the treatment of esophageal cancer. Disclosed are compositions that include an antibody binding to progastrin and disclosed are methods that include the use of an antibody binding to progastrin.
    Type: Application
    Filed: September 15, 2023
    Publication date: March 14, 2024
    Applicant: Progastrine et Cancers S.à r.l.
    Inventor: Alexandre PRIEUR
  • Compositions and methods for detecting lung cancer
    Patent number: 11913958
    Abstract: The present invention relates to methods for the in vitro diagnosis of lung cancer in a subject, comprising the detection of progastrin using at least one progastrin-binding antibody. According to the method of the invention, the subject is diagnosed with a lung cancer when progastrin is detected in the sample.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: February 27, 2024
    Assignee: ECS-Progastrin SA
    Inventor: Alexandre Prieur
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING OVARIAN CANCER
    Publication number: 20240018264
    Abstract: The present invention relates to methods for the in vitro diagnosis of ovarian cancer, and to compositions and methods for the prevention or the treatment of ovarian cancer. Disclosed are compositions that include an antibody binding to progastrin and disclosed are methods that include the use of an antibody binding to progastrin.
    Type: Application
    Filed: July 26, 2023
    Publication date: January 18, 2024
    Applicant: Progastrine et Cancers S.à r.l.
    Inventor: Alexandre PRIEUR
  • Compositions and methods for detecting and treating esophageal cancer
    Patent number: 11789021
    Abstract: The present invention relates to methods for the in vitro diagnosis of esophageal cancer, and to compositions and methods for the prevention or the treatment of esophageal cancer. Disclosed are said compositions that include an antibody binding to progastrin and disclosed are methods that include the use of an antibody binding to progastrin.
    Type: Grant
    Filed: January 2, 2017
    Date of Patent: October 17, 2023
    Assignee: PROGASTRINE ET CANCERS S.À R.L.
    Inventor: Alexandre Prieur
  • Compositions and methods for detecting and treating ovarian cancer
    Patent number: 11760808
    Abstract: The present invention relates to methods for the in vitro diagnosis of ovarian cancer, and to compositions and methods for the prevention or the treatment of ovarian cancer. Disclosed are compositions that include an antibody binding to progastrin and disclosed are methods that include the use of an antibody binding to progastrin.
    Type: Grant
    Filed: January 2, 2017
    Date of Patent: September 19, 2023
    Assignee: Progastrine et Cancers S.À R.L.
    Inventor: Alexandre Prieur
  • Compositions and methods for detecting and treating prostate cancer using progastrin binding molecule
    Patent number: 11644468
    Abstract: The present invention relates to compositions and methods for the prevention or the treatment of prostate cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: May 9, 2023
    Assignee: Progastrine et Cancers S.à r.L
    Inventor: Alexandre Prieur
  • Compositions and methods for detecting prostate cancer
    Patent number: 11614448
    Abstract: The present invention relates to compositions and methods for the in vitro diagnosis of prostate cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: March 28, 2023
    Assignee: ECS-Progastrin SA
    Inventor: Alexandre Prieur
  • Compositions and methods for treating lung cancer
    Patent number: 11561225
    Abstract: The present invention relates to compositions and methods for the prevention or the treatment of lung cancer, wherein the compositions comprise an antibody binding to progastrin and the methods comprise the use of an antibody binding to progastrin.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: January 24, 2023
    Assignee: Progastrine et Cancers S.à r.l.
    Inventor: Alexandre Prieur
  • Method for rejuvenating cells
    Patent number: 11414649
    Abstract: The invention relates to a method for reprogramming cells from aged donors or senescent cells to pluripotent cells that have lost marks of senescence. In particular, the invention relates to an ex vivo method for preparing induced pluripotent stem cells (iPSCs) from a target cell population comprising cells from aged donors or senescent cells, said method comprising the steps of culturing said target cell population under appropriate conditions for reprogramming said cells into iPSCs, wherein said appropriate conditions comprises increasing expression in said target cells, of at least the following reprogramming factors: Oct4, Klf4, Sox2, c-Myc, Lin28 and, optionally Nanog.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: August 16, 2022
    Assignees: INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE MONTPELLIER I, UNIVERSITE MONTPELLIER II
    Inventors: Alexandre Prieur, Ollivier Milhavet, Jean-Marc Lemaitre, Laure Lapasset
  • COMBINATION THERAPY BETWEEN ANTI-PROGASTRIN ANTIBODY AND IMMUNOTHERAPY TO TREAT CANCER
    Publication number: 20210324069
    Abstract: The present invention relates to combinations comprising anti-progastrin (anti-hPG) monoclonal antibodies and immune checkpoint inhibitors, as well as pharmaceutical compositions comprising said combinations. Methods of treatment of cancer using said combinations are also provided.
    Type: Application
    Filed: June 25, 2021
    Publication date: October 21, 2021
    Applicant: Progastrine et Cancers S.À R.L.
    Inventor: Alexandre Prieur
  • Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
    Patent number: 11046758
    Abstract: The present invention relates to combinations comprising anti-progastrin (anti-hPG) monoclonal antibodies and immune checkpoint inhibitors, as well as pharmaceutical compositions comprising said combinations. Methods of treatment of cancer using said combinations are also provided.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: June 29, 2021
    Assignee: PROGASTRINE ET CANCERS S.À R.L.
    Inventor: Alexandre Prieur
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING PROSTATE CANCER USING PROGASTRIN BINDING MOLECULE
    Publication number: 20210087265
    Abstract: The present invention relates to compositions and methods for the prevention or the treatment of prostate cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Application
    Filed: March 30, 2018
    Publication date: March 25, 2021
    Applicant: Progastrine et Cancers S.à r.l.
    Inventor: Alexandre Prieur
  • COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER
    Publication number: 20210085784
    Abstract: The present invention relates to compositions and methods for the prevention or the treatment of lung cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Application
    Filed: March 30, 2018
    Publication date: March 25, 2021
    Applicant: Progastrine et Cancers S.à r.l.
    Inventor: Alexandre Prieur
  • COMBINATION THERAPY BETWEEN ANTI-PROGASTRIN ANTIBODY AND IMMUNOTHERAPY TO TREAT CANCER
    Publication number: 20210009680
    Abstract: The present invention relates to combinations comprising anti-progastrin (anti-hPG) monoclonal antibodies and immune checkpoint inhibitors, as well as pharmaceutical compositions comprising said combinations. Methods of treatment of cancer using said combinations are also provided.
    Type: Application
    Filed: December 5, 2018
    Publication date: January 14, 2021
    Applicant: Progastrine et Cancers S.À R.L.
    Inventor: Alexandre Prieur
  • COMPOSITIONS AND METHODS FOR DETECTING PROSTATE CANCER
    Publication number: 20200200751
    Abstract: The present invention relates to compositions and methods for the in vitro diagnosis of prostate cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Application
    Filed: March 30, 2018
    Publication date: June 25, 2020
    Applicant: ECS-Progastrin SA
    Inventor: Alexandre Prieur
  • COMPOSITIONS AND METHODS FOR DETECTING LUNG CANCER
    Publication number: 20200103410
    Abstract: The present invention relates to compositions and methods for the in vitro diagnosis of lung cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Application
    Filed: March 30, 2018
    Publication date: April 2, 2020
    Applicant: ECS-Progastrin SA
    Inventor: Alexandre Prieur
  • METHOD FOR REJUVENATING CELLS
    Publication number: 20200095556
    Abstract: The invention relates to a method for reprogramming cells from aged donors or senescent cells to pluripotent cells that have lost marks of senescence. In particular, the invention relates to an ex vivo method for preparing induced pluripotent stem cells (iPSCs) from a target cell population comprising cells from aged donors or senescent cells, said method comprising the steps of culturing said target cell population under appropriate conditions for reprogramming said cells into iPSCs, wherein said appropriate conditions comprises increasing expression in said target cells, of at least the following reprogramming factors: Oct4, Klf4, Sox2, c-Myc, Lin28 and, optionally Nanog.
    Type: Application
    Filed: December 5, 2019
    Publication date: March 26, 2020
    Applicants: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE MONTPELLIER I, UNIVERSITE MONTPELLIER II
    Inventors: Alexandre PRIEUR, Ollivier MILHAVET, Jean-Marc LEMAITRE, Laure LAPASSET
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING ESOPHAGEAL CANCER
    Publication number: 20190011447
    Abstract: The present invention relates to methods for the in vitro diagnosis of esophageal cancer, and to compositions and methods for the prevention or the treatment of esophageal cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Application
    Filed: January 2, 2017
    Publication date: January 10, 2019
    Applicant: Progastrine et Cancers S.À R.L.
    Inventor: Alexandre Prieur
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING GASTRIC CANCER
    Publication number: 20190011449
    Abstract: The present invention relates to methods for the in vitro diagnosis of gastric cancer, and to compositions and methods for the prevention or the treatment of gastric cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Application
    Filed: January 2, 2017
    Publication date: January 10, 2019
    Applicant: Progastrine et Cancers S.À R.L.
    Inventor: Alexandre Prieur
  • COMPOSITIONS AND METHODS FOR DETECTING AND TREATING OVARIAN CANCER
    Publication number: 20190002582
    Abstract: The present invention relates to methods for the in vitro diagnosis of ovarian cancer, and to compositions and methods for the prevention or the treatment of ovarian cancer, wherein said compositions comprise an antibody binding to progastrin and said methods comprise the use of an antibody binding to progastrin.
    Type: Application
    Filed: January 2, 2017
    Publication date: January 3, 2019
    Applicant: Progastrine et Cancers S.À R.L.
    Inventor: Alexandre Prieur