Patents by Inventor ALEXANDRE SERERO

ALEXANDRE SERERO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF A DEFICIENT FUSION PROTEIN FOR NUCLEASE ACTIVITY SO AS TO INDUCE MEIOTIC RECOMBINATIONS
    Publication number: 20230174960
    Abstract: The present invention relates to a fusion protein comprising a domain of a nuclease from the class II CRISPR system, and a Spo11 domain, wherein both domains of the fusion protein have deficient nuclease activity, as well as the use of this protein to induce targeted meiotic recombinations in a eukaryotic cell.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 8, 2023
    Inventors: ALEXANDRE SERERO, ALAIN NICOLAS
  • METHOD FOR INDUCING TARGETED MEIOTIC RECOMBINATIONS
    Publication number: 20220162647
    Abstract: The present invention relates to a fusion protein comprising a Cas9 domain and a Spo11 domain, as well as the use of this protein to induce targeted meiotic recombinations in a eukaryotic cell.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 26, 2022
    Inventors: GIACOMO BASTIANELLI, ALEXANDRE SERERO, ALAIN NICOLAS
  • Method for inducing targeted meiotic recombinations
    Patent number: 11248240
    Abstract: The present invention relates to a fusion protein comprising a Cas9 domain and a Spo11 domain, as well as the use of this protein to induce targeted meiotic recombinations in a eukaryotic cell.
    Type: Grant
    Filed: January 29, 2016
    Date of Patent: February 15, 2022
    Assignees: MEIOGENIX, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITE
    Inventors: Giacomo Bastianelli, Alexandre Serero, Alain Nicolas
  • METHOD FOR INDUCING TARGETED MEIOTIC RECOMBINATIONS
    Publication number: 20180023091
    Abstract: The present invention relates to a fusion protein comprising a Cas9 domain and a Spo11 domain, as well as the use of this protein to induce targeted meiotic recombinations in a eukaryotic cell.
    Type: Application
    Filed: January 29, 2016
    Publication date: January 25, 2018
    Applicants: MEIOGENIX, INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: GIACOMO BASTIANELLI, ALEXANDRE SERERO, ALAIN NICOLAS