Patents by Inventor Alexey PCHEJETSKI

Alexey PCHEJETSKI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of preventing or treating atherosclerosis with inhibitors of specific isoenzymes of human neuraminidase
    Patent number: 11773129
    Abstract: The present invention provides a method of preventing or treating atherosclerosis or a symptom thereof comprising administering to a subject in need thereof a specific inhibitor of neuraminidase 1 (neu1); neuraminidase 3 (neu3); or a bispecific inhibitor of neu1 or neu3 of formula I; (I) and a compound of formula I.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: October 3, 2023
    Assignees: The Governors of the University of Alberta, Valorisation HSJ, Limited Partnership
    Inventors: Christopher Cairo, Alexey Pchejetski, Tianlin Guo
  • METHODS OF MODULATING LEUKOCYTES ACTIVATION AND THROMBOCYTE CLEARANCE WITH INHIBITORS OF SPECIFIC NEURAMINIDASE ISOENZYMES
    Publication number: 20220110919
    Abstract: The present invention provides a method of modulating leukocytes activation (e.g., adhesion and/or transmigration and/or cytokine response) and a method of modulating thrombocyte clearance comprising administering to a subject in need thereof a specific inhibitor of neuraminidase 1 (neu1); neuraminidase 3 (neu3) or neuraminidase 4 (neu4); or a bispecific inhibitor of neu1, neu3 or neu4 of formula (I): (I) Also provided are pharmaceutical compositions comprising the inhibitor compound of formula (1), and uses thereof for modulating leukocytes activation or modulating thrombocyte clearance.
    Type: Application
    Filed: November 29, 2019
    Publication date: April 14, 2022
    Inventors: Alexey Pchejetski, Christopher Cairo, Tianlin Guo, Md. Amran Howlader, Ekterina Demina
  • METHODS OF PREVENTING OR TREATING ATHEROSCLEROSIS WITH INHIBITORS OF SPECIFIC ISOENZYMES OF HUMAN NEURAMINIDASE
    Publication number: 20200239512
    Abstract: The present invention provides a method of preventing or treating atherosclerosis or a symptom thereof comprising administering to a subject in need thereof a specific inhibitor of neuraminidase 1 (neu1); neuraminidase 3 (neu3); or a bispecific inhibitor of neu1 or neu3 of formula I; (I) and a compound of formula I.
    Type: Application
    Filed: May 25, 2018
    Publication date: July 30, 2020
    Inventors: Christopher CAIRO, Alexey PCHEJETSKI, Tianlin GUO