Patents by Inventor Alfons Billiau

Alfons Billiau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant DNA-molecule complex for the expression of anti-human-interferon-gamma chimeric antibodies or antibody fragments
    Publication number: 20070031409
    Abstract: A method for producing biologically active Fv antibody fragments that have a neutralizing effect on the anti-viral activity of human interferon-gamma (IFN-?) by inserting an isolated nucleic acid, having nucleotide sequences that encode the VH and VL domains of the D9D10 monoclonal antibody and a nucleotide sequence that encodes a linker peptide which links the VH and VL domains, into a suitable expression vector, in order to encode FV antibody fragments. Such Fv antibody fragments can be used to treat human diseases, such as endotoxic shock, local inflammation, cerebral malaria, and autoimmune arthritis.
    Type: Application
    Filed: February 11, 2005
    Publication date: February 8, 2007
    Applicant: Stichting Rega VZW
    Inventors: Alfons Billiau, Guido Froyen