Patents by Inventor Alfred Antson

Alfred Antson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid-free anchoring of thermophilic bacteriophage G20C portal adapter into solid-state nanopores
    Patent number: 11933778
    Abstract: Hybrid nanopores, comprising a protein pore supported within a solid-state membrane, which combine the robust nature of solid-state membranes with the easily tunable and precise engineering of protein nanopores. In an embodiment, a lipid-free hybrid nanopore comprises a water soluble and stable, modified portal protein of the Thermus thermophilus bacteriophage G20c, electrokinetically inserted into a larger nanopore in a solid-state membrane. The hybrid pore is stable and easy to fabricate, and exhibits low peripheral leakage, allowing sensing and discrimination among different types of biomolecules.
    Type: Grant
    Filed: June 29, 2022
    Date of Patent: March 19, 2024
    Assignees: Northeastern University, University of York
    Inventors: Meni Wanunu, Alfred Antson, Sandra Greive, Benjamin Cressiot
  • LIPID-FREE ANCHORING OF THERMOPHILIC BACTERIOPHAGE G20C PORTAL ADAPTER INTO SOLID-STATE NANOPORES
    Publication number: 20220373533
    Abstract: Hybrid nanopores, comprising a protein pore supported within a solid-state membrane, which combine the robust nature of solid-state membranes with the easily tunable and precise engineering of protein nanopores. In an embodiment, a lipid-free hybrid nanopore comprises a water soluble and stable, modified portal protein of the Thermus thermophilus bacteriophage G20c, electrokinetically inserted into a larger nanopore in a solid-state membrane. The hybrid pore is stable and easy to fabricate, and exhibits low peripheral leakage, allowing sensing and discrimination among different types of biomolecules.
    Type: Application
    Filed: June 29, 2022
    Publication date: November 24, 2022
    Inventors: Meni Wanunu, Alfred Antson, Sandra Greive, Benjamin Cressiot
  • Lipid-free anchoring of thermophilic bacteriophage G20c portal adapter into solid-state nanopores
    Patent number: 11408880
    Abstract: Hybrid nanopores, comprising a protein pore supported within a solid-state membrane, which combine the robust nature of solid-state membranes with the easily tunable and precise engineering of protein nanopores. In an embodiment, a lipid-free hybrid nanopore comprises a water soluble and stable, modified portal protein of the Thermus thermophilus bacteriophage G20c, electrokinetically inserted into a larger nanopore in a solid-state membrane. The hybrid pore is stable and easy to fabricate, and exhibits low peripheral leakage, allowing sensing and discrimination among different types of biomolecules.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: August 9, 2022
    Assignees: Northeastern University, University of York
    Inventors: Meni Wanunu, Alfred Antson, Sandra Greive, Benjamin Cressiot
  • Lipid-Free Anchoring of Thermophilic Bacteriophage G20c Portal Adapter into Solid-State Nanopores
    Publication number: 20190360998
    Abstract: Hybrid nanopores, comprising a protein pore supported within a solid-state membrane, which combine the robust nature of solid-state membranes with the easily tunable and precise engineering of protein nanopores. In an embodiment, a lipid-free hybrid nanopore comprises a water soluble and stable, modified portal protein of the Thermus thermophilus bacteriophage G20c, electrokinetically inserted into a larger nanopore in a solid-state membrane. The hybrid pore is stable and easy to fabricate, and exhibits low peripheral leakage, allowing sensing and discrimination among different types of biomolecules.
    Type: Application
    Filed: May 17, 2019
    Publication date: November 28, 2019
    Inventors: Meni Wanunu, Alfred Antson, Sandra Greive, Benjamin Cressiot