Patents by Inventor Alfred Morgenstern

Alfred Morgenstern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of PMSA expressing cancers
    Patent number: 10980901
    Abstract: The invention relates to a method for treating PSMA expressing cancers, wherein the method comprises administering to patient in need thereof an effective amount of one or more Ac-225-radiopharmaceuticals, wherein the effective amount of said one or more Ac-225-radiopharmaceuticals is administered as a dosage of from 25 kBq to 400 kBq/kg of body weight of said patient or wherein the effective amount of said one or more Ac-225-radiopharmaceuticals is administered as a unitary dosage of from 3 MBq to 30 MBq to said patient.
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: April 20, 2021
    Assignees: The European Atomic Energy Community (EURATOM), Represented by the European Commission, Universität Heidelberg
    Inventors: Alfred Morgenstern, Frank Bruchertseifer, Christos Apostolidis, Uwe Haberkorn, Frederik Giesel, Clemens Kratochwil
  • TREATMENT OF PMSA EXPRESSING CANCERS
    Publication number: 20200016281
    Abstract: The invention relates to a method for treating PSMA expressing cancers, wherein the method comprises administering to patient in need thereof an effective amount of one or more Ac-225-radiopharmaceuticals, wherein the effective amount of said one or more Ac-225-radiopharmaceuticals is administered as a dosage of from 25 kBq to 400 kBq/kg of body weight of said patient or wherein the effective amount of said one or more Ac-225-radiopharmaceuticals is administered as a unitary dosage of from 3 MBq to 30 MBq to said patient.
    Type: Application
    Filed: December 15, 2016
    Publication date: January 16, 2020
    Inventors: Alfred MORGENSTERN, Frank BRUCHERTSEIFER, Christos APOSTOLIDIS, Uwe HABERKORN, Frederik GIESEL, Clemens KRATOCHWIL
  • SYNTHESIS OF BIOLOGICAL COMPOUNDS LABELED WITH THE ALPHA EMITTER Ac-225
    Publication number: 20150157742
    Abstract: A method is described for producing a radioconjugate labeled with radionuclide Ac-225 comprising the step of chelating said radionuclide Ac-225 with a conjugated chelate compound in a chelation reaction mixture to obtain a radioconjugate labeled with Ac-225, wherein the pH of the chelation reaction mixture is comprised between 7.1 and 10, preferably between 8.0 and 9.5, more preferably about 9.0.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 11, 2015
    Applicant: The European Atomic Energy Community (EURATOM), represented by the European Commission
    Inventors: Alfred MORGENSTERN, Frank BRUCHERTSEIFER, Christos APOSTOLIDIS
  • Radionuclides for medical use
    Patent number: 7794691
    Abstract: Methods of using Th-226 or mother radionuclides thereof, namely U-230 or Th-226, in medicine. These radionuclides are particularly appropriate for the treatment of human and/or non-human mammals, in particular for therapeutic, diagnostic (detection/imaging), prophylactic and pain palliation purposes. These radionuclides may be used in various forms for treatment and/or diagnostic purposes, in particular in cationic form or in the form of radioconjugates or bone-targeting complexes. Methods of making such radionuclides.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: September 14, 2010
    Assignee: The European Community, represented by the European Commission
    Inventors: Alfred Morgenstern, Christos Apostolidis, Roger Molinet, Klaus Luetzenkirchen
  • RADIONUCLIDES FOR MEDICAL USE
    Publication number: 20100189642
    Abstract: Methods of using Th-226 or mother radionuclides thereof, namely U-230 or Th-226, in medicine. These radionuclides are particularly appropriate for the treatment of human and/or non-human mammals, in particular for therapeutic, diagnostic (detection/imaging), prophylactic and pain palliation purposes. These radionuclides may be used in various forms for treatment and/or diagnostic purposes, in particular in cationic form or in the form of radioconjugates or bone-targeting complexes. Methods of making such radionuclides.
    Type: Application
    Filed: June 25, 2004
    Publication date: July 29, 2010
    Applicant: THE EUROPEAN COMMUNITY
    Inventors: Alfred Morgenstern, Christos Apostolidis, Roger Molinet, Klaus Luetzenkirchen
  • Method for producing actinium-225
    Publication number: 20060072698
    Abstract: A method for producing Ac-225 is presented, wherein Ac-225 is produced by bombardment of Th-232 with hydrogen isotope nuclei accelerated in a cyclotron. The method, which allows production of Ac-225 at high yields and purity levels, is particularly interesting for the supply or Ac-225 or of the daughter Bi-213 for medical applications.
    Type: Application
    Filed: June 24, 2005
    Publication date: April 6, 2006
    Inventors: Alfred Morgenstern, Christos Apostolidis, Roger Molinet, Klaus Lutzenkirchen