Patents by Inventor Ali Nadim
Ali Nadim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11473049Abstract: Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency.Type: GrantFiled: September 9, 2019Date of Patent: October 18, 2022Assignee: CLAREMONT BIOSOLUTIONS, LLCInventors: Robert Doebler, Ali Nadim, James D. Sterling, Anna Hickerson, Barbara Erwin, Denice Woyski, Ryan P. Talbot, Bruce Irvine
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Publication number: 20200002663Abstract: Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency.Type: ApplicationFiled: September 9, 2019Publication date: January 2, 2020Inventors: Robert Doebler, Ali Nadim, James D. Sterling, Anna Hickerson, Barbara Erwin, Denice Woyski, Ryan P. Talbot, Bruce Irvine
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Patent number: 10428301Abstract: Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency.Type: GrantFiled: October 20, 2016Date of Patent: October 1, 2019Assignee: Keck Graduate InstituteInventors: Robert Doebler, Ali Nadim, James D. Sterling, Anna Hickerson, Barbara Erwin, Denice Woyski, Ryan P. Talbot, Bruce Irvine
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Publication number: 20170037359Abstract: Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency.Type: ApplicationFiled: October 20, 2016Publication date: February 9, 2017Inventors: Robert Doebler, Ali Nadim, James D. Sterling, Anna Hickerson, Barbara Erwin, Denice Woyski, Ryan P. Talbot, Bruce Irvine
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Patent number: 9358540Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.Type: GrantFiled: July 22, 2015Date of Patent: June 7, 2016Assignee: KECK GRADUATE INSTITUTEInventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
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Publication number: 20160151785Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.Type: ApplicationFiled: July 22, 2015Publication date: June 2, 2016Inventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
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Patent number: 9115393Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.Type: GrantFiled: June 17, 2014Date of Patent: August 25, 2015Assignee: Keck Graduate InsituteInventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
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Publication number: 20150024480Abstract: Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency.Type: ApplicationFiled: August 4, 2014Publication date: January 22, 2015Inventors: Robert Doebler, Ali Nadim, James D. Sterling, Anna Hickerson, Barbara Erwin, Denice Woyski, Ryan P. Talbot, Bruce Irvine
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Publication number: 20140295534Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.Type: ApplicationFiled: June 17, 2014Publication date: October 2, 2014Inventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
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Patent number: 8784736Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.Type: GrantFiled: March 8, 2012Date of Patent: July 22, 2014Assignee: Keck Graduate InstituteInventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
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Patent number: 8759085Abstract: A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.Type: GrantFiled: April 29, 2011Date of Patent: June 24, 2014Assignee: Akonni Biosystems, Inc.Inventors: Phil Belgrader, Christopher G. Cooney, Robert Doebler, Anna Hickerson, Bruce Irvine, Ali Nadim, James Sterling, Reza Miraghaie
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Patent number: 8603783Abstract: A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.Type: GrantFiled: August 1, 2012Date of Patent: December 10, 2013Assignee: Akonni Biosystems, Inc.Inventors: Phillip Belgrader, Christopher G. Cooney, Robert Doebler, Anna Hickerson, Bruce Irvine, Ali Nadim, James Sterling, Reza Miraghaie
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Publication number: 20130090267Abstract: A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.Type: ApplicationFiled: August 1, 2012Publication date: April 11, 2013Inventors: Phillip BELGRADER, Christopher G. COONEY, Robert Doebler, Anna HICKERSON, Bruce IRVINE, Ali NADIM, James STERLING, Reza MIRAGHAIE
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Patent number: 8334117Abstract: A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.Type: GrantFiled: April 29, 2011Date of Patent: December 18, 2012Assignee: Akonni Biosystems, Inc.Inventors: Phil Belgrader, Christopher G. Cooney, Robert Doebler, Anna Hickerson, Bruce Irvine, Ali Nadim, James Sterling, Reza Miraghaie
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Publication number: 20120171756Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.Type: ApplicationFiled: March 8, 2012Publication date: July 5, 2012Inventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
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Patent number: 8153064Abstract: An isothermal reaction and analysis system may include a receiver to receive sample holders, a thermal control subsystem to control a temperature of the receiver, an excitation subsystem, a detection subsystem and an analysis subsystem. Excitation sources and/or detectors are positioned to enhance data collection. Sample holders may include filters, selectively blocking and passing wavelengths or bands of electromagnetic radiation.Type: GrantFiled: March 21, 2008Date of Patent: April 10, 2012Inventors: Robert W. Doebler, II, Christopher Cooney, Anna Hickerson, James D. Sterling, Ali Nadim
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Publication number: 20110207180Abstract: A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.Type: ApplicationFiled: April 29, 2011Publication date: August 25, 2011Inventors: Phil BELGRADER, Christopher G. COONEY, Robert DOEBLER, Anna HICKERSON, Bruce IRVINE, Ali NADIM, James STERLING, Reza MIRAGHAIE
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Publication number: 20110207632Abstract: A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.Type: ApplicationFiled: April 29, 2011Publication date: August 25, 2011Inventors: Phil Belgrader, Christopher G. Cooney, Robert Doebler, Anna Hickerson, Bruce Irvine, Ali Nadim, James Sterling, Reza Miraghaie
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Patent number: 7955841Abstract: A device for controlling temperature in a reaction chamber is disclosed. The device comprises: a bladder assembly comprising a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing; and a first temperature-control bladder disposed within the housing, the first temperature-control bladder is configured to receive a temperature-control fluid and comprises a flexible, heat conductive surface that comes in contact with at least a portion of an exterior surface of the reaction chamber after receiving the temperature-control fluid. Also disclosed are a bladder thermal cycler, a temperature-control bladder assembly and methods for producing a thermal cycle in a reaction chamber.Type: GrantFiled: September 22, 2008Date of Patent: June 7, 2011Assignee: Akonni BiosystemsInventors: Phil Belgrader, Christopher G. Cooney, Robert Doebler, Anna Hickerson, Bruce Irvine, Ali Nadim, James Sterling, Reza Miraghaie
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Publication number: 20100178697Abstract: Oscillating angularly rotating a container containing a material may cause the material to be separate. Denser or heavier material may unexpectedly tend to collected relatively close to the axis of rotation, while less dense or light material may tend to collect relatively away from the axis of rotation. Oscillation along an arcuate path provides high lysing efficiency. Alternatively, a micromotor may drive an impeller removably received in a container. Lysing may be implemented in batch mode, flow-through stop or semi-batch mode, or flow-through continuous mode. Lysing particulate material may exceed material to be lysed or lysed material and/or air may be essentially eliminated from a chamber to increase lysing efficiency.Type: ApplicationFiled: March 25, 2010Publication date: July 15, 2010Applicant: KECK GRADUATE INSTITUTEInventors: Robert Doebler, Ali Nadim, James D. Sterling, Anna Hickerson, Barbara Erwin, Denice Woyski, Ryan P. Talbot, Bruce Irvine