Abstract: A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

Abstract: A transcatheter valve assembly includes a main body that defines a braided stent frame having a proximal end and a distal end and a graft material covering at least a portion of the braided stent frame. The graft material is coupled to the braided stent frame at each of the proximal end and the distal end. The braided stent frame is configured to modify a length and diameter thereof to fit a diameter of a patient. A medial portion defines one of an open facing surface that is positioned proximal the coronary arteries when the valve assembly is deployed, and a pair of conduits configured for receiving a stent to fluidly engage with the coronary arteries when the valve assembly is deployed. A valve housing is at the proximal end of the transcatheter valve assembly.

Abstract: A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

Abstract: An intraluminal vascular prosthesis assembly, having a hollow cylindrical body with a first end and a second end is provided. The assembly includes, at its first end, a first vascular prosthesis portion, and at its second end, a second vascular prosthesis portion which has only a prosthesis material. The vascular prosthesis assembly has a stent portion which is provided between the first vascular prosthesis portion and the second vascular prosthesis portion, the stent portion being free of prosthesis material to allow fluid flow there through and received within the aortic arch and spanning the brachiocephalic artery, left common carotid artery, and left subclavian artery when placed within the aortic arch of a patient.

Abstract: A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

Abstract: A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

Abstract: A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes an outer frame and the seal is formed from a plurality of outwardly extending fibers.

Abstract: A heart valve assembly includes an inner frame comprising a graft covering housing a prosthetic heart valve. The graft covering extends around the prosthetic heart valve for providing sealing to the heart valve, an outer frame formed from a metallic material and defining a gridded configuration, and being secured to the graft covering by a plurality of stitches, and a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks. The sealing material includes a plurality of radially extending fibers that extend outwardly of the outer frame. The graft covering is made of polyester, polytetrafluoroethylene, expanded polytetrafluoroethylene, or a polymer.

Abstract: A prosthetic component for repair of a patient's aorta includes an uncovered portion spanning the innominate arteries, and a graft material on a proximal end thereof.

Abstract: A prosthetic component for repair of a patient's aorta includes an uncovered portion spanning the innominate arteries, and a graft material on a proximal end thereof.

Abstract: A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

Abstract: A heart valve assembly includes an outer frame. The outer frame is formed from a metallic material and defines a gridded configuration. An inner frame houses a prosthetic heart valve. The inner frame is a graft covering extending around the prosthetic heart valve for providing sealing to the heart valve. The graft covering is one of polyester, PTFE, ePTFE, or a polymer. The outer frame is secured to the graft covering. The outer frame is secured to the graft covering by a plurality of stitches. A plurality of radially extending fibers extend from the graft covering and through the outer metallic frame to form a seal positioned outwardly of the outer frame. The fibers include strands of fibers that terminate in an end thereof outwardly of the outer frame.

Abstract: A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes an outer frame and the seal is formed from a plurality of outwardly extending fibers.

Abstract: A transcatheter valve assembly replacement device includes a paravalvular seal that includes outwardly extending fibers that create a seal with the annulus when the valve assembly is deployed. An inwardly extending seal is attached to an outer frame. The inwardly extending seal is engaged with prosthetic valve leaflets.

Abstract: A heart valve assembly includes an inner frame comprising a graft covering housing a prosthetic heart valve, wherein the graft covering extends around the prosthetic heart valve for providing sealing to the heart valve, an outer frame formed from a metallic material and defining a gridded configuration, and being secured to the graft covering by a plurality of stitches, and a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks. The sealing material includes a plurality of radially extending fibers that extend outwardly of the outer frame. The graft covering is made of polyester, polytetrafluoroethylene, expanded polytetrafluoroethylene, or a polymer.

Abstract: A heart valve assembly includes an inner frame comprising a graft covering housing a prosthetic heart valve, wherein the graft covering extends around the prosthetic heart valve for providing sealing to the heart valve, an outer frame formed from a metallic material and defining a gridded configuration, and being secured to the graft covering by a plurality of stitches, and a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks. The sealing material includes a plurality of radially extending fibers that extend outwardly of the outer frame. The graft covering is made of polyester, polytetrafluoroethylene, expanded polytetrafluoroethylene, or a polymer.

Abstract: The presently disclosed subject matter is directed to a multi-spiral, self-expanding stent. The disclosed stent is constructed from superposed individual spiral strands. Each spiral strand comprises a terminal bend that separates the strand into a first portion and a second portion. Particularly, the first portion of each strand bends in a first spiral direction to the terminal bend, and the second portion bends in the opposite direction after the terminal bend. Advantageously, the disclosed stent is able to change its shape, diameter. and length to accommodate the corresponding shape, diameter, and length of patient's diseased vessel.

Abstract: A method for implanting a heart valve assembly includes positioning a bottom portion of a seal against an aortic annulus of a patient. The heart valve assembly includes an inner frame comprising a graft covering housing a prosthetic heart valve, wherein the graft covering extends around the prosthetic heart valve for providing sealing to the heart valve, an outer frame formed from a metallic material and defining a gridded configuration, and being secured to the graft covering by a plurality of stitches, and a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks. The sealing material includes a plurality of radially extending fibers that extend outwardly of the outer frame. The graft covering is made of polyester, polytetrafluoroethylene, expanded polytetrafluoroethylene, or a polymer.

Abstract: A heart valve assembly includes an inner frame comprising a graft covering housing a prosthetic heart valve, wherein the graft covering extends around the prosthetic heart valve for providing sealing to the heart valve, an outer frame formed from a metallic material and defining a gridded configuration, and being secured to the graft covering by a plurality of stitches, and a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks. The sealing material includes a plurality of radially extending fibers that extend outwardly of the outer frame. The graft covering is made of polyester, polytetrafluoroethylene, expanded polytetrafluoroethylene, or a polymer.

Abstract: A heart valve assembly includes an inner frame comprising a graft covering housing a prosthetic heart valve, wherein the graft covering extends around the prosthetic heart valve for providing sealing to the heart valve, an outer frame formed from a metallic material and defining a gridded configuration, and being secured to the graft covering by a plurality of stitches, and a sealing material positioned externally to the outer frame for providing sealing between the outer frame and a patient's anatomical wall to prevent paravalvular leaks. The sealing material includes a plurality of radially extending fibers that extend outwardly of the outer frame. The graft covering is made of polyester, polytetrafluoroethylene, expanded polytetrafluoroethylene, or a polymer.