Patents by Inventor Alice Suk-Yue Ho

Alice Suk-Yue Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of immune disorders and B cell disorders
    Publication number: 20030099650
    Abstract: The present invention provides materials and methods of using compositions comprising the IL-1Hy1 polypeptide or inhibitors of IL-1Hy1 activity for treatment of immune cell disorders.
    Type: Application
    Filed: July 25, 2002
    Publication date: May 29, 2003
    Inventors: Alice Suk-Yue Ho, John E. Ford, Hai-Shan Lin, Fabio Rupp
  • Interleukin—1 receptor antagonist and uses thereof
    Patent number: 6541623
    Abstract: The present invention provides novel nucleic acids, the novel polypeptide sequences encoded by these nucleic acids and uses thereof. These novel polynucleotide and polypeptide sequences were determined to be a novel Interleukin-1 Receptor Antagonist.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: April 1, 2003
    Assignee: Hyseq, Inc.
    Inventors: John Ford, Alice Suk-Yue Ho, Ann Pace
  • Therapeutic uses of il-1 receptor antagonist
    Patent number: 6497870
    Abstract: The present invention provides novel therapeutic methods of administering an amount of IL-1Ra to treat IL-18 related disorders. Specifically, the method involves treating IL-18 related disorders such as liver injury, hepatis, hemophagocytic lymphohistiocytosis, multiple sclerosis, tumors, cytotoxicity resulting from antitumor therapy, or other autoimmune disorders with a therapeutically effective amount of IL-1ra, and optionally measuring IFN-&ggr; and IL-18 activity from human samples.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: December 24, 2002
    Assignee: Hyseq, Inc.
    Inventors: John Ford, Alice Suk-Yue Ho
  • Novel interleukin - 1 Hy2 materials and methods
    Publication number: 20020156009
    Abstract: The present invention provides machine readable storage media comprising a three-dimensional representation of Interleukin-1 Hy2 (IL-1Hy2), useful for designing and producing modulators of its activity and IL-1 Hy2 variants, and therapeutic uses thereof. The present invention also provides novel nucleic acids encoding IL-1 Hy2, the novel polypeptides encoded by these nucleic acids and uses of these and related products.
    Type: Application
    Filed: November 2, 2001
    Publication date: October 24, 2002
    Inventors: Dennis Ballinger, John E. Ford, Alice Suk-Yue Ho, Haishan Lin, Ann Pace, Nancy K. Mize, Dana Halley-Vicente
  • Mammalian receptors for interleukin-10
    Patent number: 6423500
    Abstract: Receptor components for IL-10 are isolated and characterized. The amino acid sequence and nucleic acid encoding various species variants of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
    Type: Grant
    Filed: November 15, 1999
    Date of Patent: July 23, 2002
    Assignee: Schering Corporation
    Inventors: Kevin W. Moore, Ying Liu, Alice Suk-Yue Ho, Di-Hwei Hsu, Bazan Fernando J., Jimmy C. Tan, Chuan-Chu Chou
  • Polynucleotides encoding IL-1 Hy2 polypeptides
    Patent number: 6365726
    Abstract: The present invention provides novel nucleic acids encoding IL-1 Hy2, a novel member of the Interleukin-1 Receptor Antagonist family, the novel polypeptides encoded by these nucleic acids and uses of these and related products.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: April 2, 2002
    Assignee: Hyseq, Inc.
    Inventors: Dennis G. Ballinger, John Ford, Alice Suk-Yue Ho, Hai Shan Lin, Ann M. Pace
  • Mammalian receptors for interleukin-10 (IL-10)
    Patent number: 5985828
    Abstract: Receptor components for IL-10 are isolated and characterized. The amino acid sequence and nucleic acid encoding various species variants of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 16, 1999
    Assignee: Schering Corporation
    Inventors: Kevin W. Moore, Ying Liu, Alice Suk-Yue Ho, Di-Hwei Hsu, J. Fernando Bazan, Jimmy C. Tan, Chuan-Chu Chou
  • Antibodies which specifically bind mammalian receptors for interleukin-10 (IL-10)
    Patent number: 5863796
    Abstract: Receptor components for IL-10 are isolated and characterized. The amino acid sequence and nucleic acid encoding various species variants of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 26, 1999
    Assignee: Schering Corporation
    Inventors: Kevin W. Moore, Ying Liu, Alice Suk-Yue Ho, Di-Hwei Hsu, J. Fernando Bazan, Jimmy C. Tan, Chuan-Chu Chou
  • Mammalian receptors for interleukin-10 (IL-10)
    Patent number: 5789192
    Abstract: Receptor components for IL-10 are isolated and characterized. The amino acid sequence and nucleic acid encoding various species variants of the receptors are disclosed. Uses of the purified receptor gene and polypeptide are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
    Type: Grant
    Filed: August 23, 1993
    Date of Patent: August 4, 1998
    Assignee: Schering Corporation
    Inventors: Kevin W. Moore, Ying Liu, Alice Suk-Yue Ho, Di-Hwei Hsu, J. Fernando Bazan, Jimmy C. Tan, Chuan-Chu Chou
  • Mammalian interleukin-10 (IL-10) super-activating receptors; and variants
    Patent number: 5716804
    Abstract: Amino acid sequence and nucleic acid encoding various functional variants of the IL-10 receptors. Uses of the receptor gene and polypeptides are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
    Type: Grant
    Filed: April 19, 1995
    Date of Patent: February 10, 1998
    Assignee: Schering Corporation
    Inventors: Kevin W. Moore, Sherry Wei, Alice Suk-Yue Ho