Patents by Inventor Alicia Ferguson

Alicia Ferguson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
    Publication number: 20090082555
    Abstract: The present invention provides materials and methods to treat immune disease in which cytokines are involved in pathogenesis. The materials and methods of the present invention are useful in the treatment of autoimmune diseases. The materials and methods of the present invention are directed to nucleic acid ligands capable of binding to human IL-23 and/or human IL-12 cytokines and thus modulate their biological activity and are useful as therapeutic agents in immune, auto-immune and cancer therapeutics.
    Type: Application
    Filed: June 9, 2008
    Publication date: March 26, 2009
    Inventors: John L. Diener, Alicia Ferguson, Nobuko Hamaguchi, Sara Chesworth Keene, H.A. Daniel Lagasse, Pooja Sawhney, Kristin Thompson
  • Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
    Publication number: 20070066550
    Abstract: The present invention provides materials and methods to treat immune disease in which cytokines are involved in pathogenesis. The materials and methods of the present invention are useful in the treatment of autoimmune diseases. The materials and methods of the present invention are directed to nucleic acid ligands capable of binding to human IL-23 and/or human IL-12 cytokines and thus modulate their biological activity and are useful as therapeutic agents in immune, auto-immune and cancer therapeutics.
    Type: Application
    Filed: March 7, 2005
    Publication date: March 22, 2007
    Inventors: John Diener, Alicia Ferguson, Nobuko Hamaguchi, Sara Keene, H.A. Lagasse, Pooja Sawhney, Kristin Thompson
  • Aptamers to the human IL-12 cytokine family and their use as autoimmune disease therapeutics
    Publication number: 20060193821
    Abstract: The present invention provides materials and methods to treat immune disease in which cytokines are involved in pathogenesis. The materials and methods of the present invention are useful in the treatment of autoimmune diseases. The materials and methods of the present invention are directed to nucleic acid ligands capable of binding to human IL-23 and/or human IL-12 cytokines and thus modulate their biological activity and are useful as therapeutic agents in immune, auto-immune and cancer therapeutics.
    Type: Application
    Filed: September 22, 2005
    Publication date: August 31, 2006
    Inventors: John Diener, David Epstein, Alicia Ferguson, Nobuko Hamaguchi, H.A. Lagasse, Shannon Pendergrast, Pooja Sawhney, Kristin Thompson
  • Stabilized aptamers to platelet derived growth factor and their use as oncology therapeutics
    Publication number: 20050124565
    Abstract: Materials and methods are provided for producing and using aptamers useful as oncology therapeutics capable of binding to PDGF, PDGF isoforms, PDGF receptor, VEGF, and VEGF receptor or any combination thereof with great affinity and specificity. The compositions of the present invention are particularly useful in solid tumor therapy and can be used alone or in combination with known cytotoxic agents for the treatment of solid tumors. Also disclosed are aptamers having one or more CpG motifs embedded therein or appended thereto.
    Type: Application
    Filed: June 21, 2004
    Publication date: June 9, 2005
    Inventors: John Diener, David Epstein, Alicia Ferguson, Dilara Grate, Anthony Keefe, Thomas McCauley, Jeffrey Preiss, Martin Stanton, Charles Wilson
  • Compositions selective for caffeine or aspartame and methods of using same
    Publication number: 20030228603
    Abstract: Compositions which recognize and report on the concentration of caffeine or aspartame target molecules. The invention further relates to methods of using the compositions to monitor the presence or concentration of such targets in a variety of samples, including those samples to be ingested, such as beverages, e.g., coffee or soft drinks.
    Type: Application
    Filed: April 3, 2003
    Publication date: December 11, 2003
    Inventors: Sharon T. Cload, Alicia Ferguson