Patents by Inventor Allan Doctor

Allan Doctor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR REMOVING BIO-SYNTHETIC NANO-PARTICLES FROM BODILY FLUIDS
    Publication number: 20220287984
    Abstract: Bait and capture methods and compositions for removing bio-synthetic nano-particles from body fluids. Bio-synthetic nano-particles are baited with one-half of a bait and capture complex and lyophilized. The baited bio-synthetic nano-particle is reconstituted and administered to a subject for diagnostic or therapeutic purposes. To remove the bio-synthetic nano-particle from the body, the body fluid containing the baited bio-synthetic nano-article is contacted with the capture portion of the bait and capture complex. The body fluid from which the bio-synthetic nano-particles have been removed may be returned to the subject.
    Type: Application
    Filed: March 11, 2022
    Publication date: September 15, 2022
    Inventors: Dipanjan Pan, Allan Doctor, Nivesh Mittal
  • SELF-ASSEMBLING OXYGEN CARRIER COMPOSITIONS
    Publication number: 20210330754
    Abstract: Synthetic blood substitutes and methods for making them. A lipid-amphiphile blood-substitute precursor compound having a hydrophobic fatty acid/acyl moiety, a hydrophilic head moiety including a phosphate group, and a pH responsive moiety. The lipid-amphiphile precursor is configured to self-assemble from a solution mixture of phospholipid and cholesterol in the presence of hemoglobin and an allosteric effector into a hybrid-vesicle resulting from the combined self-assembly of both the amphiphilic lipid-oligomer and the lipids into an advanced vesicular structure containing a hemoglobin/allosteric effector payload.
    Type: Application
    Filed: April 23, 2021
    Publication date: October 28, 2021
    Inventors: Dipanjan Pan, Allan Doctor, Phil Spinella
  • BLOOD SUBSTITUTE COMPOSITION AND METHOD OF USE
    Publication number: 20170367323
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Application
    Filed: August 15, 2017
    Publication date: December 28, 2017
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Blood substitute composition and method of use
    Patent number: 9750241
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: September 5, 2017
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • BLOOD SUBSTITUTE COMPOSITION AND METHOD OF USE
    Publication number: 20170181424
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Application
    Filed: March 16, 2017
    Publication date: June 29, 2017
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Blood substitute composition and method of use
    Patent number: 9655952
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Grant
    Filed: August 9, 2016
    Date of Patent: May 23, 2017
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • BLOOD SUBSTITUTE COMPOSITION AND METHOD OF USE
    Publication number: 20160346358
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Application
    Filed: August 9, 2016
    Publication date: December 1, 2016
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Blood substitute composition and method of use
    Patent number: 9486508
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: November 8, 2016
    Assignee: WASHINGTON UNIVERSITY
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • BLOOD SUBSTITUTE COMPOSITION AND METHOD OF USE
    Publication number: 20160051635
    Abstract: The present disclosure provides oxygen-carrying nanoparticles, methods of making the nanoparticles, and methods of using the nanoparticles to carry oxygen in blood.
    Type: Application
    Filed: November 2, 2015
    Publication date: February 25, 2016
    Inventors: Gregory M. Lanza, Dipanjan Pan, Allan Doctor, Philip C. Spinella
  • Methods for identifying and measuring S-nitrosothiol bonds in heme-containing cells and molecules
    Patent number: 7763472
    Abstract: The invention provides a method of detecting an S-nitrosothiol in a sample which includes treating the sample with a transition metal such as copper (I) and cysteine in the presence of a substance capable of blocking interactions between iron-containing compounds and NO and detecting the generated NO.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: July 27, 2010
    Assignee: University of Virginia Patent Foundation
    Inventors: Allan Doctor, Benjamin M. Gaston
  • Methods For Identifying And Measuring S-Nitrosothiol Bonds In Heme-Containing Cells And Molecules
    Publication number: 20070202605
    Abstract: The invention provides a method of detecting an S-nitrosothiol in a sample which includes treating the sample with a transition metal such as copper (I) and cysteine in the presence of a substance capable of blocking interactions between iron-containing compounds and NO and detecting the generated NO.
    Type: Application
    Filed: June 16, 2005
    Publication date: August 30, 2007
    Inventors: Allan Doctor, Benjamin Gaston