Patents by Inventor Allen Laughon

Allen Laughon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for identifying and testing TGF-.beta. pathway agonists and antagonists
    Patent number: 6046165
    Abstract: The invention provides compositions and methods of identifying and testing TGF-.beta. pathway agonists and antagonists, and in particular compositions comprising Mothers against DPP (MAD) proteins and related Smad polypeptides which exhibit sequence-specific DNA-binding activity. The invention also provides a novel DNA sequence (SEQ ID NO:19); (SEQ ID NO:20); (SEQ ID NO:21) that is bound with high affinity by Drosophila MAD protein. This protein is useful for identifying compounds that will enhance or interfere with MAD protein-DNA binding.
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: April 4, 2000
    Assignee: Ophidian Pharmaceuticals, Inc.
    Inventors: Allen Laughon, Kirby Johnson, Jaeseob Kim