Patents by Inventor Allison B. Goldfine

Allison B. Goldfine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibiting striated muscle activator of RHO (stars) to improve glycemic control
    Patent number: 8815799
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of Striated Muscle Activator of Rho Signaling (STARS) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: August 26, 2014
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • INHIBITING STRIATED MUSCLE ACTIVATOR OF RHO (STARS) TO IMPROVE GLYCEMIC CONTROL
    Publication number: 20130197058
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of Striated Muscle Activator of Rho Signaling (STARS) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Application
    Filed: June 3, 2011
    Publication date: August 1, 2013
    Applicant: JOSLIN DIABETES CENTER, INC.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • Reducing risk of type 2 diabetes (T2D)
    Patent number: 8445467
    Abstract: This invention relates to methods for reducing chronic subacute inflammatory states associated with obesity and improve glycemia, thereby preventing or delaying the development of type 2 diabetes (T2D) in obese subjects, or subjects with the metabolic syndrome, using non-acetylated forms of salicylate, e.g., salsalate or trilisate.
    Type: Grant
    Filed: April 27, 2007
    Date of Patent: May 21, 2013
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Steven Shoelson, Allison B. Goldfine
  • Inhibiting Serum Response Factor (SRF) to Improve Glycemic Control
    Publication number: 20120028895
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Application
    Filed: July 11, 2011
    Publication date: February 2, 2012
    Applicant: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • Inhibiting serum response factor (SRF) to improve insulin sensitivity
    Patent number: 8003606
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: August 23, 2011
    Assignee: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • TREATMENT OF CARDIOVASCULAR DISEASE WITH SALICYLATES
    Publication number: 20110021468
    Abstract: This invention relates to methods for the treatment of atherosclerotic cardiovascular disease using a non-acetylated forms of salicylate, e.g., salsalate and/or trilisate.
    Type: Application
    Filed: July 3, 2008
    Publication date: January 27, 2011
    Applicant: JOSLIN DIABETES CENTER, INC.
    Inventors: Steven Shoelson, Allison B. Goldfine
  • Inhibiting Serum Response Factor (SRF) to Improve Glycemic Control
    Publication number: 20100010074
    Abstract: Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.
    Type: Application
    Filed: June 5, 2009
    Publication date: January 14, 2010
    Applicant: Joslin Diabetes Center, Inc.
    Inventors: Mary Elizabeth Patti, Wanzhu Jin, Allison B. Goldfine
  • REDUCING RISK OF TYPE 2 DIABETES (T2D)
    Publication number: 20090298796
    Abstract: This invention relates to methods for reducing chronic subacute inflammatory states associated with obesity and improve glycemia, thereby preventing or delaying the development of type 2 diabetes (T2D) in obese subjects, or subjects with the metabolic syndrome, using non-acetylated forms of salicylate, e.g., salsalate or trilisate.
    Type: Application
    Filed: April 27, 2007
    Publication date: December 3, 2009
    Applicant: JOSLIN DIABETES CENTER, INC.
    Inventors: Steven Shoelson, Allison B. Goldfine