Abstract: An implantable medical device including a porous membrane that is treated with a hydrophilic substance to obtain rapid optimum visualization using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.

Abstract: This invention relates to local administration of a bone-forming agent and at least one anti-resorptive agent to treat osteoporosis and related disorders.

Abstract: An implantable medical device including a porous membrane that is treated with a hydrophilic substance to obtain rapid optimum visualization using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.

Abstract: A method of rapid visualization of an implantable medical device using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.

Abstract: An implantable medical device including a porous membrane that is treated with a hydrophilic substance to obtain rapid optimum visualization using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.

Abstract: An implantable medical device including a porous membrane that is treated with a hydrophilic substance to obtain rapid optimum visualization using technology for viewing inside of a mammalian body. These technologies include ultrasound echocardiography and video imaging such as that used during laparoscopic procedures.

Abstract: There are numerous medical situations involving deficiencies of living bone or periodontal tissue and where increase of living bone or periodontal tissue mass is desired. Methods are described wherein a configured, shell-like device that is capable of being penetrated by living cells and tissues, is implanted into the body of a mammal in such a way as to establish a space, the space being at least partly, bounded by the device. The configuration of the device is such that the configuration of the established space is essentially the same as the configuration of living bone or periodontal tissue that is desired for treatment of the tissue deficiency. At least one protein from the Transforming Growth Factor-Beta Superfamily of proteins is placed within the established space for the purpose of stimulating the growth of living bone or periodontal tissue within the established space. A kit for the generation of living bone or periodontal tissue, comprised of the components mentioned above, is also disclosed.

Abstract: There are numerous medical situations involving deficiencies of living tissue and where increase of living tissue mass is desired. Methods are described wherein a configured, shell-like device that is capable of being penetrated by living cells and tissues, is implanted into the body of a mammal in such a way as to establish a space, the space being at least partly, bounded by the device. The configuration of the device is such that the configuration of the established space is essentially the same as the configuration of living tissue that is desired for treatment of the tissue deficiency. At least one tissue stimulating molecular substance is placed within the established space for the purpose of stimulating the growth of desired living tissue within the established space. A kit for the generation of desired living tissue, comprised of the components mentioned above, is also disclosed.

Abstract: The present invention is directed to hydrophobic biodegradable polymeric materials having at least one surface thereof rendered more hydrophilic by attachment of at least one layer of a hydrophilic polymer thereto. The hydrophilic polymer layer is cross-linked together on the surface of the biodegradable material with a cross-linking agent or scheme that is biodegradable. Bioactive species are immobilized to chemically functional groups of the components of the first layer or to unreacted chemically functional groups of the cross-linking agent. Optionally, the bioactive species may be reversibly immobilized through chemically functional linkages that are degradable. The result is an implantable construction with immobilized bioactive species having structural components that are all subject to degradation in the body of a recipient.

Abstract: This invention relates to local administration of a bone-forming agent and at least one anti-resorptive agent to treat osteoporosis and related disorders.