Patents by Inventor Alshad S. Lalani

Alshad S. Lalani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of hyperproliferative diseases with vinca alkaloid N-oxide analogs
    Patent number: 8883775
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Grant
    Filed: October 25, 2011
    Date of Patent: November 11, 2014
    Assignee: Cascade Prodrug Inc.
    Inventors: John G. Curd, John F. W. Keana, Alshad S. Lalani, Paul B. Westberg, Bradford Goodwin, W. David Henner
  • Mannich base N-oxide drugs
    Patent number: 8410075
    Abstract: Disclosed are Mannich base N-oxides of drugs containing acidic N—H groups. Pharmaceutical compositions comprising a therapeutically effective amount of Mannich base N-oxides, or a N-oxide rearrangement product, pharmaceutically acceptable salt or prodrug thereof, are also disclosed. Further, disclosed are methods of using the compounds, alone or in combination with one or more other active agents or treatments.
    Type: Grant
    Filed: September 21, 2009
    Date of Patent: April 2, 2013
    Assignee: Cascade Prodrug Inc.
    Inventors: John F. W. Keana, Paul Westberg, John Curd, Alshad S. Lalani
  • Treatment of Hyperproliferative Diseases with Vinca Alkaloid N-Oxide Analogs
    Publication number: 20120107230
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Application
    Filed: October 25, 2011
    Publication date: May 3, 2012
    Applicants: UNIVERSITY OF OREGON
    Inventors: JOHN G. CURD, JOHN F.W. KEANA, ALSHAD S. LALANI, PAUL B. WESTBERG, BRADFORD GOODWIN, W. DAVID HENNER
  • Treatment of hyperproliferative diseases with vinca alkaloid N-oxide and analogs
    Patent number: 8048872
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Grant
    Filed: April 29, 2008
    Date of Patent: November 1, 2011
    Assignee: Stat of Oregon Acting by and Through The Oregon State Board of Higher Education on Behalf of the University of Oregon
    Inventors: John G. Curd, John F. W. Keana, Alshad S. Lalani, Paul B. Westberg, Bradford Goodwin, W. David Henner
  • Mannich Base N-Oxide Drugs
    Publication number: 20100016252
    Abstract: Disclosed are Mannich base N-oxides of drugs containing acidic N—H groups. Pharmaceutical compositions comprising a therapeutically effective amount of Mannich base N-oxides, or a N-oxide rearrangement product, pharmaceutically acceptable salt or prodrug thereof, are also disclosed. Further, disclosed are methods of using the compounds, alone or in combination with one or more other active agents or treatments.
    Type: Application
    Filed: September 21, 2009
    Publication date: January 21, 2010
    Applicant: State of Oregon Acting By and Through The Oregon State Board of Higher Education On Behalf of The U
    Inventors: John F.W. Keana, Paul Westberg, John Curd, Alshad S. Lalani
  • Treatment of Hyperproliferative Diseases with Vinca Alkaloid N-Oxide and Analogs
    Publication number: 20080305075
    Abstract: The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
    Type: Application
    Filed: April 29, 2008
    Publication date: December 11, 2008
    Inventors: John G. Curd, John F.W. Keana, Alshad S. Lalani, Paul B. Westberg, Bradford Goodwin, W. David Henner