Patents by Inventor Alvaro Mata Chavarria

Alvaro Mata Chavarria has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structures comprising elastin-like peptides
    Patent number: 11965016
    Abstract: The present invention relates to new biomimetic mineralized apatite structures. The present invention also relates to processes for the production of new biomimetic mineralized apatite structures based on natural and synthetic protein scaffolds. In particular, the invention provides synthetic crystal having a hierarchical structure formed on an elastin-like polypeptide membrane or hydrogel. The invention also provides methods of making such crystals, both in vivo and in vitro, as well as kits comprising membranes or hydrogels with cross-linking agents and/or mineralization solutions. The invention also provides the use of such structures in methods of treatment.
    Type: Grant
    Filed: January 31, 2022
    Date of Patent: April 23, 2024
    Assignee: Mintech-V, LLC
    Inventors: Sherif Ahmed Abdelsalam Elsharkawy, Maisoon Al-Jawad, Alvaro Mata Chavarria, Esther Tejeda-Montes
  • Crystal Structures Comprising Elastin-Like Peptides
    Publication number: 20220363734
    Abstract: The present invention relates to new biomimetic mineralized apatite structures. The present invention also relates to processes for the production of new biomimetic mineralized apatite structures based on natural and synthetic protein scaffolds. In particular, the invention provides synthetic crystal having a hierarchical structure formed on an elastin-like polypeptide membrane or hydrogel. The invention also provides methods of making such crystals, both in vivo and in vitro, as well as kits comprising membranes or hydrogels with cross-linking agents and/or mineralization solutions. The invention also provides the use of such structures in methods of treatment.
    Type: Application
    Filed: January 31, 2022
    Publication date: November 17, 2022
    Inventors: Sherif Ahmed Abdelsalam Elsharkawy, Maisoon Al-Jawad, Alvaro Mata Chavarria, Esther Tejeda-Montes, Roxanna Sharon Ramnarine Sanchez
  • SELF-ASSEMBLING GRAPHENE OXIDE-PROTEIN MATRIX
    Publication number: 20210346570
    Abstract: The present invention relates to a stable self-assembling graphene oxide-protein matrix comprising a disordered protein (DP) and graphene oxide (GO), wherein the DP has an opposite charge to the GO, further wherein the graphene oxide-protein matrix is in the form of a 3D structure having a lumen defined by a membrane having an inner and outer surface. The invention further relates to methods and kits for preparing such a graphene oxide-protein matrix and its uses.
    Type: Application
    Filed: September 19, 2019
    Publication date: November 11, 2021
    Inventors: Yuanhao Wu, Wen Wang, Alvaro Mata Chavarria
  • Crystal Structures Comprising Elastin-Like Peptides
    Publication number: 20190135897
    Abstract: The present invention relates to new biomimetic mineralized apatite structures. The present invention also relates to processes for the production of new biomimetic mineralized apatite structures based on natural and synthetic protein scaffolds. In particular, the invention provides synthetic crystal having a hierarchical structure formed on an elastin-like polypeptide membrane or hydrogel. The invention also provides methods of making such crystals, both in vivo and in vitro, as well as kits comprising membranes or hydrogels with cross-linking agents and/or mineralization solutions. The invention also provides the use of such structures in methods of treatment.
    Type: Application
    Filed: April 3, 2017
    Publication date: May 9, 2019
    Inventors: Sherif Ahmed Abdelsalam Elsharkawy, Maisoon Al-Jawad, Alvaro Mata Chavarria, Esther Tejeda-Montes, Roxanna Sharon Ramnarine Sanchez
  • Method for manufacturing a three-dimensional biomimetic scaffold and uses thereof
    Patent number: 9631172
    Abstract: The present invention relates to a method for manufacturing a three-dimensional (3D) biomimetic scaffold that exploits the use of electrical fields and electrical insulating materials to pattern previously polymerized hydro gels with different molecules and/or macromolecular entities. The invention also relates to the 3D-biomimetic scaffolds obtained and to the uses and applications thereof.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: April 25, 2017
    Assignee: Queen Mary University of London
    Inventors: Alvaro Mata Chavarria, Juan Pablo Aguilar
  • Self-Assembling Peptides
    Publication number: 20150322114
    Abstract: There is provided a composition comprising a self-assembling membrane, wherein the self-assembling membrane comprises elastin-like polymers (ELPs) and peptide amphiphiles (PAs). Also provided is a method of forming a membrane and uses of the membrane.
    Type: Application
    Filed: December 24, 2013
    Publication date: November 12, 2015
    Inventors: Alvaro Mata Chavarria, Karla Inostroza, Katherine Smith, Estelle Collin
  • Method For Manufacturing A Three-Dimensional Biomimetic Scaffold And Uses Thereof
    Publication number: 20150072429
    Abstract: The present invention relates to a method for manufacturing a three-dimensional (3D) biomimetic scaffold that exploits the use of electrical fields and electrical insulating materials to pattern previously polymerized hydro gels with different molecules and/or macromolecular entities. The invention also relates to the 3D-biomimetic scaffolds obtained and to the uses and applications thereof.
    Type: Application
    Filed: January 25, 2013
    Publication date: March 12, 2015
    Inventors: Alvaro Mata Chavarria, Juan Pablo Aguilar