Patents by Inventor Alyx Caroline Guevel

Alyx Caroline Guevel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Azaindole inhibitors of MTP and ApoB
    Patent number: 7838533
    Abstract: The present invention relates to 7-azaindole-based compounds, to processes for the preparation thereof, to pharmaceutical compositions comprising them, and to the use thereof in the preparation of medicaments that are useful as inhibitors of MTP and of ApoB secretion.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: November 23, 2010
    Assignee: Merck Patent GmbH
    Inventors: Alyx Caroline Guevel, Catherine Vidal, Bruno Roux, Olivier Chevreuil
  • Novel Azaindole Inhibitors of Mtp and Apob
    Publication number: 20090036481
    Abstract: The present invention relates to 7-azaindole-based compounds, to processes for the preparation thereof, to pharmaceutical compositions comprising them, and to the use thereof in the preparation of medicaments that are useful as inhibitors of MTP and of ApoB secretion.
    Type: Application
    Filed: June 28, 2005
    Publication date: February 5, 2009
    Inventors: Alyx Caroline Guevel, Catherine Vidal, Bruno Roux, Olivier Chevreuil
  • 4-(biphenylcarbonylamino)piperidine derivatives as mtp inhibitors
    Publication number: 20040034028
    Abstract: The present invention relates to compounds of the formula (I): in which: Z represents biphenyl optionally substitute in position 2′, 3′, 4′, 5′ and 6′ with one or more substitutents chosen from trihalomethyl and trihalomethoxy; Het represents quinolyl, quinoxalyl or pyridyl optionally substituted with one or more substitutents chosen from halo, cyano, nitro, (C1-C6)alkyl, (C6-C12)aryl, (C1-C6)alkoxy, hydroxyl, (C1-C6)thioalkoxy, carboxyl and (C1-C6)alkoxycarbonyl, or pharmaceutically acceptable salts thereof. These compounds are useful as inhibitors of microsomal triglyceride transfer protein and as inhibitors of the secretion of B apoproteins.
    Type: Application
    Filed: May 22, 2003
    Publication date: February 19, 2004
    Inventors: Alyx-Caroline Guevel, Didier Festal, Francois Collonges, Daniel Guerrier, Olivier Chevreuil