Patents by Inventor Amalia Penna

Amalia Penna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus
    Patent number: 6607727
    Abstract: Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV polymerase, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: August 19, 2003
    Assignee: The Scripps Research Institute
    Inventors: Francis V. Chisari, Carlo Ferrari, Amalia Penna, Gabriele Missael
  • Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
    Patent number: 5840303
    Abstract: Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV nucleocapsid, envelope, polymerase and the transcriptional transactivator X protein, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens. Pharmaceutical compositions and hepatitis B vaccines which comprise the peptides and physiologically acceptable carriers can be employed in conjunction with other HBV vaccines to provide more effective immunity against the disease. Methods for identifying individuals who are particularly susceptible to developing chronic HBV infection and who can be targeted for treatment by the CTL peptides are also provided.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 24, 1998
    Assignee: The Scripps Research Foundation
    Inventors: Francis V. Chisari, Carlo Ferrari, Amalia Penna, Gabriele Missale