Patents by Inventor Amanda L. McClerren

Amanda L. McClerren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Two component lantibiotic and methods for producing and using the same
    Patent number: 7985837
    Abstract: The present invention relates to two-component lantibiotics isolated from Bacillus sp. Methods for producing said lantibiotics are provided, wherein dehydration and cyclization of the peptides is carried out by two substrate-specific modifying enzymes. Given the antimicrobial activity of the instant lantibiotics, methods for preventing or treating bacterial infections are also provided.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: July 26, 2011
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Wilfred A. van der Donk, Lisa E. Cooper, Amanda L. McClerren
  • Two component bacillus lantibiotic and methods for producing and using the same
    Publication number: 20080242617
    Abstract: The present invention relates to two-component lantibiotics isolated from Bacillus sp. Methods for producing said lantibiotics are provided, wherein dehydration and cyclization of the peptides is carried out by two substrate-specific modifying enzymes. Given the antimicrobial activity of the instant lantibiotics, methods for preventing or treating bacterial infections are also provided.
    Type: Application
    Filed: October 31, 2007
    Publication date: October 2, 2008
    Inventors: Wilfred A. van der Donk, Lisa E. Cooper, Amanda L. McClerren