Patents by Inventor Amani S. Awaad

Amani S. Awaad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9233096
    Abstract: The present invention relates to methods of isolating flavonoids from Euphorbia cuneata, and a pharmaceutical composition comprising the flavonoids or the extracts or both of them for a use as anti-ulcer agent. The present invention further relates to a method of providing an anti-ulcer treatment to an animal in need thereof comprising administering to the animal a compound selected from 4?-methoxy-luteolin-7-O-rhamnoglucoside and aromadendrin. A method of providing an anti-ulcer treatment to an animal in need thereof comprising administering to the animal a compound selected from 4?-methoxy-luteolin-7-O-rhamnoglucoside and aromadendrin, in which the compound(s) are isolated from Euphorbia cuneata.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: January 12, 2016
    Assignee: King Saud University
    Inventors: Amani S. Awaad, Reham Moustafa El-Meligy
  • Patent number: 9192639
    Abstract: The Convolvulus extract for treating peptic ulcer and Helicobacter pylori infection is an ethanolic extract from C. pilosellifolius. The extract is prepared by homogenizing Convolvulus pilosellifolius aerial plant parts to prepare a powder, percolating the powder with an organic solvent to prepare a suspension, filtering the suspension to obtain a filtrate, and obtaining the extract as a dry powder by drying the solvent under reduced pressure from the filtrate. The active ingredient in the extract is a compound that was isolated from the extract of C. pilosellifolius as a purified triterpene using silica gel column chromatography, the compound being named: 2-propoxyethyl 13-(4-ethoxy-4-oxobutyl)-6b,8a12b,14a-tetramethyl-5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,14a-tetradecahydropicene-2-carboxylate. Both the extract and the isolated active ingredient exhibit anti-ulcerogenic activity, and disk diffusion tests show that various strains of H. pylori are susceptible to both the extract and the active ingredient.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: November 24, 2015
    Assignee: KING SAUD UNIVERSITY
    Inventors: Amani S. Awaad, Asma'a Al-Rifai, Reham M. El-Meligy, Mohamed E. Zain
  • Patent number: 9073500
    Abstract: The present invention relates to a thermal insulation construction comprising a support and a thermal insulation layer thereon, wherein the thermal insulation layer comprises an extract from a plant material obtainable from Aloe Vera, a method for the preparation thereof and its use, in particular, for thermal insulating a vehicle interior.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: July 7, 2015
    Assignee: King Saud University
    Inventors: Amani S. Awaad, Reham Moustafa El-Meligy, Sara H. Alqahtani, Hessa E. Alduhailan
  • Patent number: 8933267
    Abstract: The present invention relates to a compound according to formula I in particular as anti-ulcer agent and/or anti-Helicobacter pylori agent, wherein R1 is selected from linear or branched C1-C6 alkyl, H, thioether and benzyl, and R2 is selected from linear or branched C1-C10 alkanediyl and pharmaceutical compositions thereof.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: January 13, 2015
    Assignee: King Saud University
    Inventors: Amani S. Awaad, Reham Moustafa El-Meligy, Ahmed M. Alafeefy
  • Publication number: 20140329778
    Abstract: The present invention relates to a compound according to formula I in particular as anti-ulcer agent and/or anti-Helicobacter pylori agent, wherein R1 is selected from linear or branched C1-C6 alkyl, H, thioether and benzyl, and R2 is selected from linear or branched C1-C10 alkanediyl and pharmaceutical compositions thereof
    Type: Application
    Filed: March 13, 2014
    Publication date: November 6, 2014
    Applicant: King Saud University
    Inventors: Amani S. AWAAD, Reham Moustafa EL-MELIGY, Ahmed M. ALAFEEFY
  • Publication number: 20140288016
    Abstract: The present invention relates to methods of isolating flavonoids from Euphorbia cuneata, and a pharmaceutical composition comprising the flavonoids or the extracts or both of them for a use as anti-ulcer agent. The present invention further relates to a method of providing an anti-ulcer treatment to an animal in need thereof comprising administering to the animal a compound selected from 4?-methoxy-luteolin-7-O-rhamnoglucoside and aromadendrin. A method of providing an anti-ulcer treatment to an animal in need thereof comprising administering to the animal a compound selected from 4?-methoxy-luteolin-7-O-rhamnoglucoside and aromadendrin, in which the compound(s) are isolated from Euphorbia cuneata.
    Type: Application
    Filed: June 5, 2014
    Publication date: September 25, 2014
    Inventors: Amani S. AWAAD, Reham Moustafa EL-MELIGY
  • Publication number: 20140288286
    Abstract: The present invention relates to methods to isolate flavonoids from Euphorbia cuneata, and a pharmaceutical composition comprising the flavonoids or the extracts or both of them for a use as anti-ulcer agent. The present invention further relates to a method to isolate a compound selected from the group consisting of 4?-methoxy-luteolin-7-O-rhamnoglucoside and/or aromadendrin from Euphorbia cuneata.
    Type: Application
    Filed: June 5, 2014
    Publication date: September 25, 2014
    Inventors: Amani S. AWAAD, Reham Moustafa EL-MELIGY
  • Publication number: 20140077118
    Abstract: The present invention relates to a thermal insulation construction comprising a support and a thermal insulation layer thereon, wherein the thermal insulation layer comprises an extract from a plant material obtainable from Aloe Vera, a method for the preparation thereof and its use, in particular, for thermal insulating a vehicle interior.
    Type: Application
    Filed: September 9, 2013
    Publication date: March 20, 2014
    Applicant: King Saud University
    Inventors: Amani S. AWAAD, Reham Moustafa EL-MELIGY, Sara H. ALQAHTANI, Hessa E. ALDUHAILAN
  • Publication number: 20130224239
    Abstract: The present invention relates to an alcoholic extract of fungi of the genus Cunninghamella; a method for its preparation and use thereof.
    Type: Application
    Filed: February 16, 2012
    Publication date: August 29, 2013
    Applicant: KING SAUD UNIVERSITY
    Inventors: Amani S. Awaad, Gamal A. Soliman, Nabila A. Aljaber, Tahani A. Al-Hamad
  • Publication number: 20130079294
    Abstract: The present invention relates to flavonoids isolated from Euphorbia cuneata, a method for their isolation, extracts from Euphorbia cuneata and a pharmaceutical composition comprising the flavonoids or the extracts or both of them for a use as anti-ulcer agent.
    Type: Application
    Filed: July 9, 2012
    Publication date: March 28, 2013
    Applicant: KING SAUD UNIVERSITY
    Inventors: Amani S. Awaad, Reham Moustafa El-Meligy