Patents by Inventor Amgad Salah Moussa

Amgad Salah Moussa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11168341
    Abstract: The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: November 9, 2021
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jäger, Wolfgang Beckmann, Amgad Salah Moussa, Guenter Olf, Guido Becker, Hasan Akyildiz, Andreas Damm, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
  • Patent number: 11155844
    Abstract: The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: October 26, 2021
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jäger, Amgad Salah Moussa, Simon Klaffl, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
  • Patent number: 10968466
    Abstract: The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) adsorbing aminobenzoic acid; (III) desorbing aminobenzoic acid at a pH in the range from ?0.8 to 3.0, preferably ?0.5 to 3.0, more preferably 0.1 to 3.0, very preferably 0.5 to 2.5, very exceptionally preferably 1.0 to 2.0; (IV) obtaining the aminobenzoic acid from the desorbate obtained in step (III); (V) optionally further converting the aminobenzoic acid obtained in step (IV) to an aminobenzoic acid conversion product.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: April 6, 2021
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jäger, Ivonne Görtz, Giulio Lolli, Amgad Salah Moussa, Thomas Hamedinger
  • Patent number: 10731187
    Abstract: The invention provides a recombinant microbial host cell capable of converting a raw material comprising a fermentable carbon substrate to o-aminobenzoate biologically. The invention further provides a method for producing aniline, comprising the steps of: a) producing o-aminobenzoate by fermentation of a raw material comprising at least one fermentable carbon substrate using the recombinant microbial host cell of the capable of converting said raw material comprising at least one fermentable carbon substrate to o-aminobenzoate biologically, wherein said o-aminobenzoate comprises anthranilate anion, b) converting said o-aminobenzoate from said anthranilate anion to anthranilic acid by acid protonation, c) recovering said anthranilic acid by precipitation or by dissolving in an organic solvent, and d) converting said anthranilic acid to aniline by thermal decarboxylation in an organic solvent.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: August 4, 2020
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa, Guenter Olf, Giulio Lolli, Swantje Behnken, Jung-Won Youn, Mohammad Yalfani, Georg Sprenger
  • Patent number: 10703709
    Abstract: The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: July 7, 2020
    Assignee: Covestro Deutschland AG
    Inventors: Gernot Jäger, Thomas Hamedinger, Giulio Lolli, Amgad Salah Moussa, Guenter Olf
  • Publication number: 20190382812
    Abstract: The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) adsorbing aminobenzoic acid; (III) desorbing aminobenzoic acid at a pH in the range from ?0.8 to 3.0, preferably ?0.5 to 3.0, more preferably 0.1 to 3.0, very preferably 0.5 to 2.5, very exceptionally preferably 1.0 to 2.0; (IV) obtaining the aminobenzoic acid from the desorbate obtained in step (III); (V) optionally further converting the aminobenzoic acid obtained in step (IV) to an aminobenzoic acid conversion product.
    Type: Application
    Filed: December 18, 2017
    Publication date: December 19, 2019
    Inventors: Gernot JÄGER, Ivonne GÖRTZ, Giulio LOLLI, Amgad Salah MOUSSA, Thomas HAMEDINGER
  • Publication number: 20190233365
    Abstract: The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.
    Type: Application
    Filed: June 27, 2017
    Publication date: August 1, 2019
    Inventors: Gernot JÄGER, Thomas HAMEDINGER, Giulio LOLLI, Amgad Salah MOUSSA, Guenter Olf
  • Patent number: 10173969
    Abstract: The invention relates to a method for producing aniline, comprising the steps of: a) providing o-aminobenzoate, wherein said o-aminobenzoate comprises anthranilate anion and a suitable cation, b) converting said anthranilate anion to aniline by thermal decarboxylation in the presence or absence of a catalyst, c) extracting the aniline produced in step b) in an organic solvent at least once, and d) purifying the aniline produced in steps b) and c) by distillation, wherein said distillation produces aniline and a water phase.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: January 8, 2019
    Assignee: COVESTRO DEUTSCHLAND AG
    Inventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa
  • Publication number: 20180371512
    Abstract: The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.
    Type: Application
    Filed: December 14, 2016
    Publication date: December 27, 2018
    Inventors: Gernot JÄEGER, Amgad Salah MOUSSA, Simon KLAFFL, Thomas HAMEDINGER, Wolf KLOECKNER, Swantje BEHNKEN
  • Publication number: 20180334694
    Abstract: The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.
    Type: Application
    Filed: November 17, 2016
    Publication date: November 22, 2018
    Inventors: Gernot Jäger, Wolfgang Beckmann, Amgad Salah Moussa, Guenter Olf, Guido Becker, Hasan Akyildiz, Andreas Damm, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
  • Publication number: 20170152535
    Abstract: The invention provides a recombinant microbial host cell capable of converting a raw material comprising a fermentable carbon substrate to o-aminobenzoate biologically. The invention further provides a method for producing aniline, comprising the steps of: a) producing o-aminobenzoate by fermentation of a raw material comprising at least one fermentable carbon substrate using the recombinant microbial host cell of the capable of converting said raw material comprising at least one fermentable carbon substrate to o-aminobenzoate biologically, wherein said o-aminobenzoate comprises anthranilate anion, b) converting said o-aminobenzoate from said anthranilate anion to anthranilic acid by acid protonation, c) recovering said anthranilic acid by precipitation or by dissolving in an organic solvent, and d) converting said anthranilic acid to aniline by thermal decarboxylation in an organic solvent.
    Type: Application
    Filed: February 19, 2015
    Publication date: June 1, 2017
    Inventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa, Guenter Olf, Giulio Lolli, Swantje Behnken, Jung-Won Youn, Mohammad Yalfani, Georg Sprenger
  • Publication number: 20170066713
    Abstract: The invention relates to a method for producing aniline, comprising the steps of: a) providing o-aminobenzoate, wherein said o-aminobenzoate comprises anthranilate anion and a suitable cation, b) converting said anthranilate anion to aniline by thermal decarboxylation in the presence or absence of a catalyst, c) extracting the aniline produced in step b) in an organic solvent at least once, and d) purifying the aniline produced in steps b) and c) by distillation, wherein said distillation produces aniline and a water phase.
    Type: Application
    Filed: February 19, 2015
    Publication date: March 9, 2017
    Inventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa
  • Patent number: 9518006
    Abstract: The invention relates to an industrial-scale method for the vapor-phase hydrogenation of dinitrotoluene (DNT). According to said method, a stream containing DNT is sprayed into a carrier-gas stream containing hydrogen, optionally in the presence of an atomizing gas, unevaporated liquid droplets are extracted from the substantially gaseous stream that is obtained and the resultant gas stream is catalytically hydrogenated to form diaminotoluene.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: December 13, 2016
    Assignee: Covestro Deutschland AG
    Inventors: Bernd Pennemann, Amgad Salah Moussa, Bastian Mahr
  • Patent number: 9447021
    Abstract: The present invention relates to a process for the purification of aniline which originates from gas phase hydrogenations. In this process, only a minimum proportion of the aniline has to be evaporated and condensed again. The process is highly efficient in removing compounds which have phenolic hydroxyl groups and results in minimal losses of aniline. This process also reduces the unwanted coupling mechanisms in the division of the overall crude product in the fraction condensation into individual substreams and the subsequent workup of these.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: September 20, 2016
    Assignee: Covestro Deutschland AG
    Inventors: Michael Merkel, Peter Lehner, Bastian Mahr, Amgad Salah Moussa
  • Publication number: 20160244402
    Abstract: The invention relates to an industrial-scale method for the vapor-phase hydrogenation of dinitrotoluene (DNT). According to said method, a stream containing DNT is sprayed into a carrier-gas stream containing hydrogen, optionally in the presence of an atomizing gas, unevaporated liquid droplets are extracted from the substantially gaseous stream that is obtained and the resultant gas stream is catalytically hydrogenated to form diaminotoluene.
    Type: Application
    Filed: October 2, 2014
    Publication date: August 25, 2016
    Inventors: Bernd Pennemann, Amgad Salah Moussa, Bastian Mahr
  • Patent number: 9233910
    Abstract: The invention relates to a process for purifying aniline produced by gas-phase hydrogenation of nitrobenzene, by fractional condensation of the crude reaction product obtained in gaseous form so that at least two liquid process products, a partial condensate (PK) and a total condensate (TK), are obtained.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: January 12, 2016
    Assignee: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Peter Lehner, Knut Sommer, Amgad Salah Moussa
  • Publication number: 20150080610
    Abstract: The present invention relates to a process for the purification of aniline which originates from gas phase hydrogenations. In this process, only a minimum proportion of the aniline has to be evaporated and condensed again. The process is highly efficient in removing compounds which have phenolic hydroxyl groups and results in minimal losses of aniline. This process also reduces the unwanted coupling mechanisms in the division of the overall crude product in the fraction condensation into individual substreams and the subsequent workup of these.
    Type: Application
    Filed: March 18, 2013
    Publication date: March 19, 2015
    Inventors: Michael Merkel, Peter Lehner, Bastian Mahr, Amgad Salah Moussa
  • Publication number: 20140046096
    Abstract: The invention relates to a process for purifying aniline produced by gas-phase hydrogenation of nitrobenzene, by fractional condensation of the crude reaction product obtained in gaseous form so that at least two liquid process products, a partial condensate (PK) and a total condensate (TK), are obtained, wherein the condensation leading to the formation of PK is carried out at higher temperature than the temperature leading to the formation of TK, a product stream originating from PK and a product stream originating from TK are each passed separately from one another into a distillation column consisting of at least one stripping section and at least one rectifying section, wherein the product stream originating from PK is introduced into the lower section of the distillation column between the lowermost stripping section and the section which follows, and the product stream originating from TK is introduced into the top of the distillation column above the uppermost rectifying section, and the desired purif
    Type: Application
    Filed: October 17, 2011
    Publication date: February 13, 2014
    Applicant: BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Peter Lehner, Knut Sommer, Amgad Salah Moussa
  • Publication number: 20130327086
    Abstract: The present invention relates to a process for simplified separation of a reaction product (P) from reaction gas mixtures by means of partial condensation of the reaction gas mixture consisting of the reaction product (P), at least one high boiler (H) and at least one low boiler (L).
    Type: Application
    Filed: October 17, 2011
    Publication date: December 12, 2013
    Applicant: BAYER INTELLECTUAL PROPERTY GmbH
    Inventors: Amgad Salah Moussa, Peter Lehner, Knut Sommer