Patents by Inventor Amgad Salah Moussa
Amgad Salah Moussa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11168341Abstract: The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.Type: GrantFiled: November 17, 2016Date of Patent: November 9, 2021Assignee: Covestro Deutschland AGInventors: Gernot Jäger, Wolfgang Beckmann, Amgad Salah Moussa, Guenter Olf, Guido Becker, Hasan Akyildiz, Andreas Damm, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
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Patent number: 11155844Abstract: The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.Type: GrantFiled: December 14, 2016Date of Patent: October 26, 2021Assignee: Covestro Deutschland AGInventors: Gernot Jäger, Amgad Salah Moussa, Simon Klaffl, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
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Patent number: 10968466Abstract: The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) adsorbing aminobenzoic acid; (III) desorbing aminobenzoic acid at a pH in the range from ?0.8 to 3.0, preferably ?0.5 to 3.0, more preferably 0.1 to 3.0, very preferably 0.5 to 2.5, very exceptionally preferably 1.0 to 2.0; (IV) obtaining the aminobenzoic acid from the desorbate obtained in step (III); (V) optionally further converting the aminobenzoic acid obtained in step (IV) to an aminobenzoic acid conversion product.Type: GrantFiled: December 18, 2017Date of Patent: April 6, 2021Assignee: Covestro Deutschland AGInventors: Gernot Jäger, Ivonne Görtz, Giulio Lolli, Amgad Salah Moussa, Thomas Hamedinger
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Patent number: 10731187Abstract: The invention provides a recombinant microbial host cell capable of converting a raw material comprising a fermentable carbon substrate to o-aminobenzoate biologically. The invention further provides a method for producing aniline, comprising the steps of: a) producing o-aminobenzoate by fermentation of a raw material comprising at least one fermentable carbon substrate using the recombinant microbial host cell of the capable of converting said raw material comprising at least one fermentable carbon substrate to o-aminobenzoate biologically, wherein said o-aminobenzoate comprises anthranilate anion, b) converting said o-aminobenzoate from said anthranilate anion to anthranilic acid by acid protonation, c) recovering said anthranilic acid by precipitation or by dissolving in an organic solvent, and d) converting said anthranilic acid to aniline by thermal decarboxylation in an organic solvent.Type: GrantFiled: February 19, 2015Date of Patent: August 4, 2020Assignee: Covestro Deutschland AGInventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa, Guenter Olf, Giulio Lolli, Swantje Behnken, Jung-Won Youn, Mohammad Yalfani, Georg Sprenger
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Patent number: 10703709Abstract: The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.Type: GrantFiled: June 27, 2017Date of Patent: July 7, 2020Assignee: Covestro Deutschland AGInventors: Gernot Jäger, Thomas Hamedinger, Giulio Lolli, Amgad Salah Moussa, Guenter Olf
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Publication number: 20190382812Abstract: The present invention relates to a process for preparing aminobenzoic acid or an aminobenzoic acid conversion product, comprising the steps of: (I) providing an aqueous solution of aminobenzoic acid using a fermentation process; (II) adsorbing aminobenzoic acid; (III) desorbing aminobenzoic acid at a pH in the range from ?0.8 to 3.0, preferably ?0.5 to 3.0, more preferably 0.1 to 3.0, very preferably 0.5 to 2.5, very exceptionally preferably 1.0 to 2.0; (IV) obtaining the aminobenzoic acid from the desorbate obtained in step (III); (V) optionally further converting the aminobenzoic acid obtained in step (IV) to an aminobenzoic acid conversion product.Type: ApplicationFiled: December 18, 2017Publication date: December 19, 2019Inventors: Gernot JÄGER, Ivonne GÖRTZ, Giulio LOLLI, Amgad Salah MOUSSA, Thomas HAMEDINGER
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Publication number: 20190233365Abstract: The invention relates to a method for producing aniline or products that are obtained by further chemical reaction of aniline (aniline derivatives), involving decarboxylation of aminobenzoic acid, particularly ortho-aminobenzoic acid, in which one portion of the previously formed crude aniline is recirculated in the decarboxylation step. The aminobenzoic acid is obtained enzymatically or chemically, preferably enzymatically.Type: ApplicationFiled: June 27, 2017Publication date: August 1, 2019Inventors: Gernot JÄGER, Thomas HAMEDINGER, Giulio LOLLI, Amgad Salah MOUSSA, Guenter Olf
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Patent number: 10173969Abstract: The invention relates to a method for producing aniline, comprising the steps of: a) providing o-aminobenzoate, wherein said o-aminobenzoate comprises anthranilate anion and a suitable cation, b) converting said anthranilate anion to aniline by thermal decarboxylation in the presence or absence of a catalyst, c) extracting the aniline produced in step b) in an organic solvent at least once, and d) purifying the aniline produced in steps b) and c) by distillation, wherein said distillation produces aniline and a water phase.Type: GrantFiled: February 19, 2015Date of Patent: January 8, 2019Assignee: COVESTRO DEUTSCHLAND AGInventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa
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Publication number: 20180371512Abstract: The present invention relates to the production of o-aminobenzoic acid from fermentable substrates using yeast cells.Type: ApplicationFiled: December 14, 2016Publication date: December 27, 2018Inventors: Gernot JÄEGER, Amgad Salah MOUSSA, Simon KLAFFL, Thomas HAMEDINGER, Wolf KLOECKNER, Swantje BEHNKEN
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Publication number: 20180334694Abstract: The invention relates to a method for producing aminobenzoic acid or a aminobenzoic acid derivative via the fermentation of a suitable raw material under the influence of suitable microorganisms and obtaining a fermentation broth containing aminobenzoate and/or aminobenzoic acid. In particular, the invention relates to the step of obtaining the aminobenzoic acid from the fermentation broth, wherein the crystallisation of aminobenzoic acid is carried out via a simple one-stage acid treatment in the presence of seed crystals. The aminobenzoic acid crystallised in this simple manner can be easily separated from the mother liquor, further cleaned if necessary, and then supplied to the different applications.Type: ApplicationFiled: November 17, 2016Publication date: November 22, 2018Inventors: Gernot Jäger, Wolfgang Beckmann, Amgad Salah Moussa, Guenter Olf, Guido Becker, Hasan Akyildiz, Andreas Damm, Thomas Hamedinger, Wolf Kloeckner, Swantje Behnken
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Publication number: 20170152535Abstract: The invention provides a recombinant microbial host cell capable of converting a raw material comprising a fermentable carbon substrate to o-aminobenzoate biologically. The invention further provides a method for producing aniline, comprising the steps of: a) producing o-aminobenzoate by fermentation of a raw material comprising at least one fermentable carbon substrate using the recombinant microbial host cell of the capable of converting said raw material comprising at least one fermentable carbon substrate to o-aminobenzoate biologically, wherein said o-aminobenzoate comprises anthranilate anion, b) converting said o-aminobenzoate from said anthranilate anion to anthranilic acid by acid protonation, c) recovering said anthranilic acid by precipitation or by dissolving in an organic solvent, and d) converting said anthranilic acid to aniline by thermal decarboxylation in an organic solvent.Type: ApplicationFiled: February 19, 2015Publication date: June 1, 2017Inventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa, Guenter Olf, Giulio Lolli, Swantje Behnken, Jung-Won Youn, Mohammad Yalfani, Georg Sprenger
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Publication number: 20170066713Abstract: The invention relates to a method for producing aniline, comprising the steps of: a) providing o-aminobenzoate, wherein said o-aminobenzoate comprises anthranilate anion and a suitable cation, b) converting said anthranilate anion to aniline by thermal decarboxylation in the presence or absence of a catalyst, c) extracting the aniline produced in step b) in an organic solvent at least once, and d) purifying the aniline produced in steps b) and c) by distillation, wherein said distillation produces aniline and a water phase.Type: ApplicationFiled: February 19, 2015Publication date: March 9, 2017Inventors: Gernot Jaeger, Jorgen Magnus, Amgad Salah Moussa
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Patent number: 9518006Abstract: The invention relates to an industrial-scale method for the vapor-phase hydrogenation of dinitrotoluene (DNT). According to said method, a stream containing DNT is sprayed into a carrier-gas stream containing hydrogen, optionally in the presence of an atomizing gas, unevaporated liquid droplets are extracted from the substantially gaseous stream that is obtained and the resultant gas stream is catalytically hydrogenated to form diaminotoluene.Type: GrantFiled: October 2, 2014Date of Patent: December 13, 2016Assignee: Covestro Deutschland AGInventors: Bernd Pennemann, Amgad Salah Moussa, Bastian Mahr
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Patent number: 9447021Abstract: The present invention relates to a process for the purification of aniline which originates from gas phase hydrogenations. In this process, only a minimum proportion of the aniline has to be evaporated and condensed again. The process is highly efficient in removing compounds which have phenolic hydroxyl groups and results in minimal losses of aniline. This process also reduces the unwanted coupling mechanisms in the division of the overall crude product in the fraction condensation into individual substreams and the subsequent workup of these.Type: GrantFiled: March 18, 2013Date of Patent: September 20, 2016Assignee: Covestro Deutschland AGInventors: Michael Merkel, Peter Lehner, Bastian Mahr, Amgad Salah Moussa
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Publication number: 20160244402Abstract: The invention relates to an industrial-scale method for the vapor-phase hydrogenation of dinitrotoluene (DNT). According to said method, a stream containing DNT is sprayed into a carrier-gas stream containing hydrogen, optionally in the presence of an atomizing gas, unevaporated liquid droplets are extracted from the substantially gaseous stream that is obtained and the resultant gas stream is catalytically hydrogenated to form diaminotoluene.Type: ApplicationFiled: October 2, 2014Publication date: August 25, 2016Inventors: Bernd Pennemann, Amgad Salah Moussa, Bastian Mahr
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Patent number: 9233910Abstract: The invention relates to a process for purifying aniline produced by gas-phase hydrogenation of nitrobenzene, by fractional condensation of the crude reaction product obtained in gaseous form so that at least two liquid process products, a partial condensate (PK) and a total condensate (TK), are obtained.Type: GrantFiled: October 17, 2011Date of Patent: January 12, 2016Assignee: BAYER INTELLECTUAL PROPERTY GMBHInventors: Peter Lehner, Knut Sommer, Amgad Salah Moussa
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Publication number: 20150080610Abstract: The present invention relates to a process for the purification of aniline which originates from gas phase hydrogenations. In this process, only a minimum proportion of the aniline has to be evaporated and condensed again. The process is highly efficient in removing compounds which have phenolic hydroxyl groups and results in minimal losses of aniline. This process also reduces the unwanted coupling mechanisms in the division of the overall crude product in the fraction condensation into individual substreams and the subsequent workup of these.Type: ApplicationFiled: March 18, 2013Publication date: March 19, 2015Inventors: Michael Merkel, Peter Lehner, Bastian Mahr, Amgad Salah Moussa
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Publication number: 20140046096Abstract: The invention relates to a process for purifying aniline produced by gas-phase hydrogenation of nitrobenzene, by fractional condensation of the crude reaction product obtained in gaseous form so that at least two liquid process products, a partial condensate (PK) and a total condensate (TK), are obtained, wherein the condensation leading to the formation of PK is carried out at higher temperature than the temperature leading to the formation of TK, a product stream originating from PK and a product stream originating from TK are each passed separately from one another into a distillation column consisting of at least one stripping section and at least one rectifying section, wherein the product stream originating from PK is introduced into the lower section of the distillation column between the lowermost stripping section and the section which follows, and the product stream originating from TK is introduced into the top of the distillation column above the uppermost rectifying section, and the desired purifType: ApplicationFiled: October 17, 2011Publication date: February 13, 2014Applicant: BAYER INTELLECTUAL PROPERTY GMBHInventors: Peter Lehner, Knut Sommer, Amgad Salah Moussa
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Publication number: 20130327086Abstract: The present invention relates to a process for simplified separation of a reaction product (P) from reaction gas mixtures by means of partial condensation of the reaction gas mixture consisting of the reaction product (P), at least one high boiler (H) and at least one low boiler (L).Type: ApplicationFiled: October 17, 2011Publication date: December 12, 2013Applicant: BAYER INTELLECTUAL PROPERTY GmbHInventors: Amgad Salah Moussa, Peter Lehner, Knut Sommer