Patents by Inventor Amilcare Bertoni

Amilcare Bertoni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the synthesis of nabumetone
    Patent number: 5750793
    Abstract: New process for the synthesis of the antiinflammatory drug known as nabumetone that consists in reacting 2-acetyl-5-bromo-6-methoxynaphthalene with an alkyl acetate in presence of an alkaline alcoholate to get 4-(5-bromo-6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2-one that by catalytic hydrogenation in a polar solvent and in presence of a base gives 4-(6-methoxy-2-naphthyl)butan-2-one known as nabumetone.
    Type: Grant
    Filed: January 23, 1997
    Date of Patent: May 12, 1998
    Assignee: Alfa Chemicals Italiana S.p.A.
    Inventors: Vincenzo Cannata, Amilcare Bertoni, Stefano Bianchi
  • Process for the synthesis of nabumetone
    Patent number: RE37813
    Abstract: New process for the synthesis of the antiinflammatory drug known as nabumetone that consists in reacting 2-acetyl-5-bromo-6-methoxynaphthalene with an alkyl acetate in presence of an alkaline alcoholate to get 4-(5-bromo-6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2-one that by catalytic hydrogenation in a polar solvent and in presence of a base gives 4-(6-methoxy-2-naphthyl)butan-2-one known as nabumetone.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: August 6, 2002
    Assignee: Honeywell International Inc.
    Inventors: Vincenzo Cannata, Amilcare Bertoni, Stefano Bianchi