Abstract: If a critical event occurs during a boot process, an information handling system may analyze firmware associated with the critical event to determine whether the firmware is unified extensible firmware interface compliant. In response to determining that the firmware is not unified extensible firmware interface compliant, the system may retrieve a rule associated with the firmware, and apply one or more actions to the information handling system based on the rule.

Abstract: Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.

Abstract: If a critical event occurs during a boot process, an information handling system may analyze firmware associated with the critical event to determine whether the firmware is unified extensible firmware interface compliant. In response to determining that the firmware is not unified extensible firmware interface compliant, the system may retrieve a rule associated with the firmware, and apply one or more actions to the information handling system based on the rule.

Abstract: An information handling system may include a processor, a memory communicatively coupled to the processor, a communications port communicatively coupled to the processor, and a basic input/output system (BIOS) comprising boot firmware configured to be executed by the processor of the information handling system when the information handling system is booted and/or powered on, and configured to initialize information handling resources of the information handling system and/or initialize interoperation of the information handling system with other information handling systems, the BIOS further configured to: responsive to a failure to complete a phase of execution of the BIOS, create a virtual disk on the memory such that the virtual disk is mountable as a volume by a second information handling system coupled to the information handling system via the communications port, and store telemetry information relevant to the failure to the virtual disk.

Abstract: A method may include, in an operating system executing on an information handling system, obtaining information regarding basic input/output system (BIOS) configuration security controls, evaluating the BIOS configuration security controls to determine if the BIOS configuration security controls satisfy a standard for performing a BIOS-managed BIOS firmware update, and if the BIOS configuration security controls fail to satisfy the standard for performing the BIOS-managed BIOS firmware update, configuring the BIOS configuration security controls to enforce a secure BIOS update policy on a subsequent boot of the information handling system and triggering a warm reboot of the information handling system.

Abstract: Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.

Abstract: Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.

Abstract: Described herein are compositions, formulations, and methods useful for sensitizing cancer cells to chemotherapeutic agents, for inhibiting expression or translation of oncogenic proteins, for inhibiting eIF4A, for inhibiting c-MYC, for reducing sternness of breast cancer cells, for treating breast cancer, for overcoming drug resistance of drug-resistant cancer cells, and for reducing tumor cell viability, involving one or more inhibitors of eIF4A, LASP1, CXCR4, CXCL8, CXCL12, ROCK1, BIRC5, MDM2, CCND1, and c-MYC.

Abstract: Thieno-pyrimidin-4-yl-hydrazinylidene compounds, and methods of using the same, are described.

Abstract: Compounds, compositions, and methods useful for inducing cancer cell death via methuosis, autophagy, or a combination thereof, are described. The compounds have a 4-pyridyl group linked by a heterocyclic group to an aryl, heteroaryl, aralkyl, or heteroaryl alkyl.