Patents by Inventor Ammon B. Peck
Ammon B. Peck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160041151Abstract: The present invention features compositions and methods for the detection or measurement of oxalate in a sample. Such compositions include test devices that provide for the rapid and accurate detection of oxalate in a sample from a biological fluid. Advantageously, the compositions can be used to monitor the oxalate levels of a patient at a point of care (e.g., at the patient's home, clinic, physician's office, or other clinical setting).Type: ApplicationFiled: May 20, 2015Publication date: February 11, 2016Inventors: Ammon B. Peck, Cuong Q. Nguyen, Nigel G. John Richards
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Patent number: 9045794Abstract: The present invention features compositions and methods for the detection or measurement of oxalate in a sample. Such compositions include test devices that provide for the rapid and accurate detection of oxalate in a sample from a biological fluid. Advantageously, the compositions can be used to monitor the oxalate levels of a patient at a point of care (e.g., at the patient's home, clinic, physician's office, or other clinical setting).Type: GrantFiled: February 7, 2012Date of Patent: June 2, 2015Assignee: University of Florida Research Foundation, Inc.Inventors: Ammon B. Peck, Cuong Q. Nguyen, Nigel G. John Richards
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Publication number: 20140113284Abstract: Disclosed herein are PNA probes, or PNA probe sets and their use as well as kits useful for the analysis of certain Oxalobacter species and/or strain(s) present in a sample of interest. Probe sequences may sequence that are at least about 86% identical to the nucleobase sequence or complement thereof selected from the following sequences: GACAATGTAGAGTTGACT (SED ID NO. 1); caggatggtcagaagttc (SEQ ID NO. 2); CCGGTTACATCGAAGGA (SEQ ID NO. 3); and AATGTAGAGTTG ACT (SEQ ID NO. 4).Type: ApplicationFiled: November 1, 2011Publication date: April 24, 2014Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.Inventors: Cuong Q. Nguyen, Ammon B. Peck
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Publication number: 20130330760Abstract: The present invention features compositions and methods for the detection or measurement of oxalate in a sample. Such compositions include test devices that provide for the rapid and accurate detection of oxalate in a sample from a biological fluid. Advantageously, the compositions can be used to monitor the oxalate levels of a patient at a point of care (e.g., at the patient's home, clinic, physician's office, or other clinical setting).Type: ApplicationFiled: February 7, 2012Publication date: December 12, 2013Applicant: University of Florida Research FoundationInventors: Ammon B. Peck, Cuong Q. Nguyen, Nigel G. John Richards
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Publication number: 20100178652Abstract: The subject invention provides materials and methods for the detection, prevention, and treatment of diabetes and other autoimmune conditions.Type: ApplicationFiled: January 7, 2008Publication date: July 15, 2010Inventors: Sally A. Litherland, Marcia McDuffie, Laurence Morel, Federica Seydel, Erin Garrigan, Nicole S. Belkin, Bryan Stutevoss, Michael J. Clare-Salzler, Mark A. Atkinson, Clive Henry Wasserfall, Ammon B. Peck, Abdolreza Davoodi-Semiromi
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Publication number: 20080274090Abstract: The subject invention concerns new methods which make it possible, for the first time, to grow functional islet-producing stem cells (IPSCs), islet progenitor cells (IPCs) and IPC-derived islets (IdIs) in in vitro cultures. The subject invention also concerns the use of the in vitro grown IPSCs, IPCs and/or IdIs for implantation into a mammal for in vivo therapy of diabetes. The subject invention further concerns a process of using the implanted cells for growing a pancreas-like structure in vivo that has the same functional, morphological and histological characteristics as those observed in normal pancreatic endocrine tissue. The ability to grow these cells in vitro and pancreas-like structures in vivo opens up important new avenues for research and therapy relating to diabetes.Type: ApplicationFiled: January 25, 2008Publication date: November 6, 2008Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.Inventors: Ammon B. Peck, Janet G. Cornelius, Vijayakumar K. Ramiya
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Patent number: 6929940Abstract: The subject invention pertains to polynucleotides encoding the enzyme oxalate decarboxylase from the filamentous fungus Aspergillus niger and methods of use. The subject invention also pertains to methods of using the enzyme oxalate decarboxylase from Bacillus subtilis.Type: GrantFiled: August 20, 2003Date of Patent: August 16, 2005Assignee: University of Florida Research Foundation, Inc.Inventors: Nigel Gordon John Richards, Christopher Harry Chang, Ammon B. Peck
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Patent number: 6709820Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes. The subject invention also concerns methods for detecting the presence of Oxalobacter formigenes organisms in a sample, and the polynucleotide probes and primers used in the detection method.Type: GrantFiled: April 9, 2001Date of Patent: March 23, 2004Assignee: University of Florida Research Foundation, Inc.Inventors: Ammon B. Peck, Harmeet Sidhu
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Patent number: 6703017Abstract: The subject invention concerns new methods which make it possible, for the first time, to grow functional islet-producing stem cells (IPSCs), islet progenitor cells (IPCs) and IPC-derived islets (IdIs) in in vitro cultures. The subject invention also concerns the use of the in vitro grown IPSCs, IPCs and/or IdIs for implantation into a mammal for in vivo therapy of diabetes. The subject invention further concerns a process of using the implanted cells for growing a pancreas-like structure in vivo that has the same functional, morphological and histological characteristics as those observed in normal pancreatic endocrine tissue. The ability to grow these cells in vitro and pancreas-like structures in vivo opens up important new avenues for research and therapy relating to diabetes.Type: GrantFiled: September 27, 1999Date of Patent: March 9, 2004Assignees: Ixion Biotechnology, Inc., University of FloridaInventors: Ammon B. Peck, Janet Cornelius, Vijayakumar K. Ramiya
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Publication number: 20040038286Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes. The subject invention also concerns methods for detecting the presence of Oxalobacter formigenes organisms in a sample, and the polynucleotide probes and primers used in the detection method.Type: ApplicationFiled: September 8, 2003Publication date: February 26, 2004Inventors: Ammon B. Peck, Harmeet Sidhu
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Publication number: 20020081681Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes. The subject invention also concerns methods for detecting the presence of Oxalobacter formigenes organisms in a sample, and the polynucleotide probes and primers used in the detection method.Type: ApplicationFiled: April 9, 2001Publication date: June 27, 2002Inventors: Ammon B. Peck, Harmeet Sidhu
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Publication number: 20010011130Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes.Type: ApplicationFiled: January 8, 2001Publication date: August 2, 2001Inventor: Ammon B. Peck
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Patent number: 6214980Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes. The subject invention also concerns methods for detecting the presence of Oxalobacter formigenes organisms in a sample, and the polynucleotide probes and primers used in the detection method.Type: GrantFiled: September 23, 1997Date of Patent: April 10, 2001Assignee: University of FloridaInventors: Ammon B. Peck, Harmeet Sidhu
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Patent number: 6090628Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes. The subject invention also concerns methods for detecting the presence of Oxalobacter formigenes organisms in a sample, and the polynucleotide probes and primers used in the detection method.Type: GrantFiled: June 26, 1997Date of Patent: July 18, 2000Assignee: University of FloridaInventors: Ammon B. Peck, Harmeet Sidhu
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Patent number: 6001647Abstract: The subject invention concerns new methods which make it possible, for the first time, to grow functional islets in in vitro cultures. The subject invention also concerns the use of the in vitro grown islet-like structures for implantation into a mammal for in vivo therapy of diabetes. The subject invention further concerns a process using the in vitro grown islet implants for growing an organ in vivo that has the same functional, morphological and histological characteristics as those observed in normal pancreatic tissue. The ability to grow these cells in vitro and organs in vivo opens up important new avenues for research and therapy relating to diabetes.Type: GrantFiled: October 25, 1995Date of Patent: December 14, 1999Assignee: Ixion Biotechnology, Inc.Inventors: Ammon B. Peck, Janet G. Cornelius
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Patent number: 5912125Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes. The subject invention also concerns methods for detecting the presence of Oxalobacter formigenes organisms in a sample, and the polynucleotide probes and primers used in the detection method.Type: GrantFiled: September 27, 1996Date of Patent: June 15, 1999Assignee: University of FloridaInventors: Ammon B. Peck, Harmeet Sidhu
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Patent number: 5837833Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate. The subject invention further concerns the cloning, sequencing and expression of the genes that encode the formyl-CoA transferase enzyme and the oxalyl-CoA decarboxylase enzyme of Oxalobacter formigenes. The subject invention also concerns a method for detecting the presence of Oxalobacter formigenes organisms in a sample, and the polynucleotide probes and primers used in the detection method.Type: GrantFiled: June 20, 1995Date of Patent: November 17, 1998Assignee: University of Florida Research Foundation, Inc.Inventor: Ammon B. Peck
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Patent number: 5834308Abstract: The subject invention concerns new methods which make it possible, for the first time, to grow functional islet cells in in vitro cultures. The ability to grow these cells opens up important new avenues for research and therapy relating to diabetes.Type: GrantFiled: April 28, 1994Date of Patent: November 10, 1998Assignee: University of Florida Research Foundation, Inc.Inventors: Ammon B. Peck, Janet G. Cornelius
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Patent number: 5604111Abstract: The subject invention concerns the novel use of formyl-CoA transferase enzyme together with oxalyl-CoA decarboxylase enzyme for the detection and measurement of oxalate in biological samples. The use of the enzyme system according to the subject invention results in the conversion of oxalate into carbon dioxide and formate. Because the production of formate is directly correlated to the concentration of oxalate present in a sample, the determination of the resulting formate concentration provides an accurate, sensitive and rapid means for detecting even low levels of oxalate.Type: GrantFiled: June 20, 1994Date of Patent: February 18, 1997Assignee: University of Florida Research FoundationInventor: Ammon B. Peck