Abstract: The present invention disclosed a continuous flow and batch process for the separation of metal or metal oxide nanoparticles continuously in a periodic manner at the liquid-liquid interface using a centrifugal separator cum extractor, wherein the nanoparticles are collected at the liquid-liquid interface of the polar and non-polar liquids.

Abstract: A continuous flow reactor without any moving parts to facilitate solid-liquid reaction without clogging is disclosed herein. It comprises plurality of identical cavities in series/sequence, each cavity being provided with: a pair of inlets at the top to allow entry of reactants into the reactor; an outlet at the bottom to allow the reactants to the next cavity for mixing; and a jacket covering around the cavities to provide heating or cooling effect as per the requirement. The outlet of the previous cavity is inclined at a suitable angle relative to the outlet of the next cavity to prevent clogging and facilitate efficient mixing of the reactants.

Abstract: The present disclosure provides a continuous process for the synthesis coupled compounds of diazonium salts including azo dyes involving in-situ generation of diazonium salts. It further discloses a set up to carry out the process for the synthesis of coupled compounds of diazonium salts.

Abstract: A continuous flow process for the synthesis of metal nanowires using a bubble column reactor. Also disclosed are different types of multiphase bubble column reactors for synthesizing metal nanowires in high yields and purity through a continuous process. The continuous process provides tunability for the aspect ratio of the nanowires.

Abstract: The present invention provides a continuous solvent free and additive free process for the synthesis of Metformin Hydrochloride in a screw reactor. >90% conversion of the solid substrates without solvent is obtained in a screw reactor to produce Metformin Hydrochloride with at least 90% selectivity.

Abstract: The present invention discloses a process for the oxidation of fatty acids comprises reacting fatty acid with O2 containing O3 for a period of 0.1-60 min at a temp in the range of ?78 to 30 deg C. to obtain the corresponding products, wherein the conversion of the fatty acid is in the range of 80% to 100% and the process is catalyst free and co-oxidant free.

Abstract: The present disclosed an improved process for the synthesis of ivacaftor starting from indole acetic acid ester which can be performed in batch as well as continuous flow synthesis. The present invention further disclosed to a continuous process for the synthesis of compound of formula (II) or formula (III) from compound of formula (I) in continuous flow reactor.

Abstract: The present invention disclosed a continuous flow and batch process for the separation of metal or metal oxide nanoparticles continuously in a periodic manner at the liquid-liquid interface using a centrifugal separator cum extractor, wherein the nanoparticles are collected at the liquid-liquid interface of the polar and non-polar liquids.

Abstract: The present invention disclosed an efficient, continuous flow process for the synthesis metal nanowires by using a continuous stirred tank reactor (CSTRs) in series for varying the aspect ratio of metal nanowires and nanorods formed by feeding affixed quantities of metal salt and polymeric surfactant with a reducing solvent like glycol to an axially mixed reactor.

Abstract: A multimodal micromixer obstacle for intensification of mixing and performing the reaction in a continuous manner is disclosed herein. The micromixer 100 comprises of plurality of inlets, an outlet and a plurality of channels. The end channels—of the channels, have plurality—of converging sections having width, to depth ratio ranging 1:1 to 20:1. The intermediate channels have at least, one obstacle having non-circular shape. Each converging section is incomplete ellipse, prolate or oblate shaped having, angle of curvature in the range of 90 to 270°. Axes of the inlets are coplanar and perpendicular to the channels. All the components of the micromixer are coplanar.

Abstract: The present disclosed an improved process for the synthesis of ivacaftor starting from indole acetic acid ester which can be performed in batch as well as continuous flow synthesis. The present invention further disclosed to a continuous process for the synthesis of compound of formula (II) or formula (III) from compound of formula (I) in continuous flow reactor.

Abstract: A Continuous flow synthesis of nanocrystalline metal oxides by rapid sol-gel process is disclosed. The process disclosed uses an impinging microjet micromixer device to obtain the nano crystalline metal oxides. A method of fabricating and assembling the impinging microjet micromixer is also disclosed herewith.

Abstract: A multimodal micromixer obstacle for intensification of mixing and performing the reaction in a continuous manner is disclosed herein. The micromixer 100 comprises of plurality of inlets, an outlet and a plurality of channels. The end channels—of the channels, have plurality—of converging sections having width, to depth ratio ranging 1:1 to 20:1. The intermediate channels have at least, one obstacle having non-circular shape. Each converging section is incomplete ellipse, prolate or oblate shaped having, angle of curvature in the range of 90 to 270°. Axes of the inlets are coplanar and perpendicular to the channels. All the components of the micromixer are coplanar.

Abstract: A tube in tube continuous glass lined metal reactor includes: concentric tubular segments; (a) outer glass lined tube and (b) an inner glass lined segment disposed in the outer glass lined tube, defining thereby an intermediate glass lined region between the inner segment and the outer tube.

Abstract: A device which can be used as a flow reactor for synthesis and for discerning the reaction kinetics as well as a flow calorimeter is a need in the art. To fulfill this need, the invention discloses a simple calorimeter that functions as a device to measure reaction kinetics, preferably heat of reaction in a continuous manner, in adiabatic as well as in isothermal conditions. The distinct advantages of the device include online determination of thermokinetic properties, continuous determination of thermokinetic properties and applicable for determination in adiabatic as well as isothermal modes. The device may function independently or may be used in combination with reactors, micro reactors or tubular reactors.

Abstract: A method for treating effluent provides the effluent as an input to an apparatus having a vortex diode with aeration. The apparatus induces a cavitation assisted with aeration for the high rates of ammoniacal nitrogen in an orifice and the vortex diode with or without inserts/stabilizers to generate radicals, which reduce ammoniacal nitrogen of wastewater effectively during effluent treatments.

Abstract: A method for treating effluent provides the effluent as an input to an apparatus having a vortex diode with aeration. The apparatus induces a cavitation assisted with aeration for the high rates of ammoniacal nitrogen in an orifice and the vortex diode with or without inserts/stabilizers to generate radicals, which reduce ammoniacal nitrogen of wastewater effectively during effluent treatments.

Abstract: The invention disclosed herein relates to tube in tube in tube continuous glass lined metal reactor with enhanced heat transfer efficiency. Particularly, the reactor comprising three concentric tubular segments; (a) inner glass lined tube [105]; (b) intermediate glass lined tube and (c) outer glass lined tube [104]; wherein the heat transfer fluid flows in the areas of segment [104] and [105] and reactant flow between the inner and outer glass lined tubes or their annulus.

Abstract: The present invention discloses a flow reactor composed of plurality of modular/fluidic components that helps retain agility and re-configurability of the continuous chemical processes with improved processing ability. More specifically, disclosed herein is a continuous flow reactor composed of varied permutations and combinations of a plurality of modular/fluidic components for chemical processing. The components are connected to each other using connectors that facilitate the connection of either with two or more, similar or different components.

Abstract: The present invention discloses device that can generate a strong vortex in the vortex chamber which significantly enhances rate of reactions and effectiveness of waste water treatment. The present invention disclose vortex diodes with or without inserts/stabilizers as continuous flow reactors to induce cavitation to generate radicals which reduces Chemical Oxygen Demand (COD), ammoniacal nitrogen and color of waste water effectively in effluent treatments.