Patents by Inventor Amol SOIN

Amol SOIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240148300
    Abstract: An electrical stimulation system for delivering spatially random electrical stimulation to a patient through an electrode array according to one embodiment includes an electrode array comprising a plurality of electrodes spaced apart from one another, a signal generator electrically coupled to the electrode array and configured to deliver an electrical stimulation signal, and a controller comprising a processor and a memory having a plurality of instructions stored thereon that, in response to execution by the processor, causes the controller to randomly select an electrical configuration from the plurality of electrodes of the electrode array by randomly selecting a first set of electrodes of the plurality of electrodes to function as electrical sources and a second set of electrodes of the plurality of electrodes to function as electrical sinks, and to instruct the signal generator to deliver the electrical stimulation signal to the patient via the randomly selected electrical configuration.
    Type: Application
    Filed: November 9, 2022
    Publication date: May 9, 2024
    Inventors: Eric A. Schepis, Amol Soin
  • Patent number: 11964155
    Abstract: A method of rapid frequency cycling during electrical stimulation according to an embodiment may include determining, by a controller of an electrical stimulation system, a plurality of frequency band groupings of discrete frequency bands of an electrical stimulation signal having a frequency range, wherein each frequency band grouping includes at least one discrete frequency band, wherein a corresponding current or voltage amplitude of the electrical stimulation signal is independently tuned within each discrete frequency band based on feedback received from a patient, determining, by the controller, a random sequence of the frequency band groupings of the plurality of frequency band groupings, generating, by at least one signal generator controlled by the controller, the electrical stimulation signal according to the determined random sequence of the frequency band groupings, and delivering the generated electrical stimulation signal through an electrode array to the patient to provide therapy to the patien
    Type: Grant
    Filed: July 14, 2023
    Date of Patent: April 23, 2024
    Assignee: Soin Neuroscience, LLC
    Inventors: Amol Soin, Eric A. Schepis
  • Patent number: 11925805
    Abstract: A method of providing electrical stimulation therapy to a patient according to one embodiment includes generating an un-tuned electrical noise signal by at least one noise generator, partitioning the un-tuned electrical noise signal into a plurality of discrete frequency bands having corresponding bandwidths, delivering the un-tuned electrical noise signal through one or more electrodes to the patient to target the patient's central or peripheral nervous system, adjusting, for each of a plurality of selected frequency bands, an amplitude of the voltage or current of the un-tuned electrical noise signal within a corresponding frequency band to generate an adjusted electrical stimulation signal based on feedback received from the patient, wherein the adjusted electrical stimulation signal includes a plurality of local maxima and a plurality of local minima, and delivering the adjusted electrical stimulation signal through the electrodes to provide electrical stimulation therapy to the patient.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: March 12, 2024
    Assignee: Soin Neuroscience, LLC
    Inventors: Eric A. Schepis, Amol Soin
  • Patent number: 11903633
    Abstract: The present invention is directed to a system and method for adaptive multivariate control for performing a radiofrequency (RF) ablation procedure with an energy delivery device. The system includes an energy source for delivering energy to a patient's body; one or more energy delivery devices; two or more sensors for measuring at least two factors related to an ablation procedure, respectively; and at least one processor.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: February 20, 2024
    Assignee: Avent, Inc.
    Inventors: Eric A. Schepis, Ryan B. Caldwell, Jalpa S. Shah, Lee C. Burnes, Amol Soin
  • Patent number: 11793443
    Abstract: A method of providing therapy to a patient according to one embodiment includes partitioning a frequency range into a plurality of discrete frequency bands with each having a corresponding bandwidth, generating a composite electrical signal based on a plurality of periodic signals, wherein each periodic signal has a frequency within a corresponding frequency band of the plurality of discrete frequency bands, delivering the composite electrical signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or a current of the composite electrical signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.
    Type: Grant
    Filed: November 9, 2022
    Date of Patent: October 24, 2023
    Assignee: Soin Neuroscience, LLC
    Inventors: Eric A Schepis, Amol Soin
  • Patent number: 11766559
    Abstract: A method of providing therapy to a patient according to one embodiment includes generating an electrical noise signal by at least one noise generator controlled by a controller of a tunable noise system, partitioning the electrical noise signal into a plurality of discrete frequency bands, each of the discrete frequency bands having a corresponding bandwidth, delivering the electrical noise signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or current of the electrical noise signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted electrical signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: September 26, 2023
    Assignee: Soin Neuroscience, LLC
    Inventors: Eric A. Schepis, Amol Soin
  • Publication number: 20230240580
    Abstract: A method of providing therapy to a patient according to one embodiment includes partitioning a frequency range into a plurality of discrete frequency bands with each having a corresponding bandwidth, generating a composite electrical signal based on a plurality of periodic signals, wherein each periodic signal has a frequency within a corresponding frequency band of the plurality of discrete frequency bands, delivering the composite electrical signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or a current of the composite electrical signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.
    Type: Application
    Filed: November 9, 2022
    Publication date: August 3, 2023
    Inventors: Eric A. Schepis, Amol Soin
  • Publication number: 20230158304
    Abstract: A method of providing electrical stimulation therapy to a patient according to one embodiment includes generating an un-tuned electrical noise signal by at least one noise generator, partitioning the un-tuned electrical noise signal into a plurality of discrete frequency bands having corresponding bandwidths, delivering the un-tuned electrical noise signal through one or more electrodes to the patient to target the patient's central or peripheral nervous system, adjusting, for each of a plurality of selected frequency bands, an amplitude of the voltage or current of the un-tuned electrical noise signal within a corresponding frequency band to generate an adjusted electrical stimulation signal based on feedback received from the patient, wherein the adjusted electrical stimulation signal includes a plurality of local maxima and a plurality of local minima, and delivering the adjusted electrical stimulation signal through the electrodes to provide electrical stimulation therapy to the patient.
    Type: Application
    Filed: December 5, 2022
    Publication date: May 25, 2023
    Inventors: Eric A. Schepis, Amol Soin
  • Publication number: 20230012663
    Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.
    Type: Application
    Filed: September 19, 2022
    Publication date: January 19, 2023
    Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
  • Patent number: 11446498
    Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: September 20, 2022
    Assignee: Avent, Inc.
    Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
  • Publication number: 20220202471
    Abstract: The present invention is directed to a system and method for adaptive multivariate control for performing a radiofrequency (RF) ablation procedure with an energy delivery device. The system includes an energy source for delivering energy to a patient's body; one or more energy delivery devices; two or more sensors for measuring at least two factors related to an ablation procedure, respectively; and at least one processor.
    Type: Application
    Filed: December 30, 2020
    Publication date: June 30, 2022
    Inventors: Eric A. Schepis, Ryan B. Caldwell, Jalpa S. Shah, Lee C. Burnes, Amol Soin
  • Publication number: 20220169508
    Abstract: The present invention relates to pharmaceutical compositions of nitrites such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The pharmaceutical compositions, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO2?). The pharmaceutical compositions of the invention are useful, for example, for treating or reducing pain, improving symptoms of a microvascular disease, and improving nerve conduction velocity.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Amol SOIN, Christopher KEVIL, Kyle CHAN, Anthony GIORDANO
  • Publication number: 20220105344
    Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.
    Type: Application
    Filed: December 17, 2021
    Publication date: April 7, 2022
    Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
  • Publication number: 20220096822
    Abstract: A method of providing therapy to a patient according to one embodiment includes generating an electrical noise signal by at least one noise generator controlled by a controller of a tunable noise system, partitioning the electrical noise signal into a plurality of discrete frequency bands, each of the discrete frequency bands having a corresponding bandwidth, delivering the electrical noise signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or current of the electrical noise signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted electrical signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.
    Type: Application
    Filed: December 8, 2021
    Publication date: March 31, 2022
    Inventors: Eric A. Schepis, Amol Soin
  • Patent number: 11247902
    Abstract: The present invention relates to pharmaceutical compositions of nitrites such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The pharmaceutical compositions, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO2?). The pharmaceutical compositions of the invention are useful, for example, for treating or reducing pain, improving symptoms of a microvascular disease, and improving nerve conduction velocity.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: February 15, 2022
    Inventors: Amol Soin, Christopher Kevil, Kyle Chan, Anthony Giordano
  • Patent number: 11202909
    Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.
    Type: Grant
    Filed: November 9, 2020
    Date of Patent: December 21, 2021
    Assignee: Avent, Inc.
    Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
  • Publication number: 20210052899
    Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.
    Type: Application
    Filed: November 9, 2020
    Publication date: February 25, 2021
    Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
  • Patent number: 10828491
    Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: November 10, 2020
    Assignee: Avent, Inc.
    Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
  • Patent number: 10792496
    Abstract: The exemplified systems and methods facilitate a nerve conduction block at a target nerve using electrical stimulation applied from one or more electrodes located on a percutaneous lead that are placed in parallel, or substantially in parallel, and without direct contact, to a long axis of the peripheral nerve over an overlapping nerve region of greater than about 3 millimeters. The exemplified system and method can be further configured to block nerve condition without eliciting onset activity and co-excitation of non-targeted structures. The exemplified method and system can be performed using conventional percutaneous leads, though an improved percutaneous lead design is disclosed herein. In an aspect, an introducer is disclosed that facilitates accurate and consistent insertion of the percutaneous lead to the specified or intended position relative to the target nerve. In another aspect, a treatment kit comprising the various system components to treat pain is disclosed.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: October 6, 2020
    Assignee: Avent, Inc.
    Inventors: Eric A. Schepis, Phillip A. Schorr, Shyamy R. Sastry, Ryan Caldwell, David M. Page, Amol Soin
  • Patent number: 10780270
    Abstract: The exemplified systems and methods facilitate a nerve conduction block at a target nerve using electrical stimulation applied from one or more electrodes located on a percutaneous lead that are placed in parallel, or substantially in parallel, and without direct contact, to a long axis of the peripheral nerve over an overlapping nerve region of greater than about 3 millimeters. The exemplified system and method can be further configured to block nerve condition without eliciting onset activity and co-excitation of non-targeted structures. The exemplified method and system can be performed using conventional percutaneous leads, though an improved percutaneous lead design is disclosed herein. In an aspect, an introducer is disclosed that facilitates accurate and consistent insertion of the percutaneous lead to the specified or intended position relative to the target nerve. In another aspect, a treatment kit comprising the various system components to treat pain is disclosed.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: September 22, 2020
    Assignee: Avent, Inc.
    Inventors: Eric A. Schepis, Phillip A. Schorr, Wanzhan Liu, Natalia Alexeeva, Shyamant R. Sastry, Amol Soin, David M. Page, Ryan Caldwell