Patents by Inventor Amol SOIN
Amol SOIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148300Abstract: An electrical stimulation system for delivering spatially random electrical stimulation to a patient through an electrode array according to one embodiment includes an electrode array comprising a plurality of electrodes spaced apart from one another, a signal generator electrically coupled to the electrode array and configured to deliver an electrical stimulation signal, and a controller comprising a processor and a memory having a plurality of instructions stored thereon that, in response to execution by the processor, causes the controller to randomly select an electrical configuration from the plurality of electrodes of the electrode array by randomly selecting a first set of electrodes of the plurality of electrodes to function as electrical sources and a second set of electrodes of the plurality of electrodes to function as electrical sinks, and to instruct the signal generator to deliver the electrical stimulation signal to the patient via the randomly selected electrical configuration.Type: ApplicationFiled: November 9, 2022Publication date: May 9, 2024Inventors: Eric A. Schepis, Amol Soin
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Patent number: 11964155Abstract: A method of rapid frequency cycling during electrical stimulation according to an embodiment may include determining, by a controller of an electrical stimulation system, a plurality of frequency band groupings of discrete frequency bands of an electrical stimulation signal having a frequency range, wherein each frequency band grouping includes at least one discrete frequency band, wherein a corresponding current or voltage amplitude of the electrical stimulation signal is independently tuned within each discrete frequency band based on feedback received from a patient, determining, by the controller, a random sequence of the frequency band groupings of the plurality of frequency band groupings, generating, by at least one signal generator controlled by the controller, the electrical stimulation signal according to the determined random sequence of the frequency band groupings, and delivering the generated electrical stimulation signal through an electrode array to the patient to provide therapy to the patienType: GrantFiled: July 14, 2023Date of Patent: April 23, 2024Assignee: Soin Neuroscience, LLCInventors: Amol Soin, Eric A. Schepis
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Patent number: 11925805Abstract: A method of providing electrical stimulation therapy to a patient according to one embodiment includes generating an un-tuned electrical noise signal by at least one noise generator, partitioning the un-tuned electrical noise signal into a plurality of discrete frequency bands having corresponding bandwidths, delivering the un-tuned electrical noise signal through one or more electrodes to the patient to target the patient's central or peripheral nervous system, adjusting, for each of a plurality of selected frequency bands, an amplitude of the voltage or current of the un-tuned electrical noise signal within a corresponding frequency band to generate an adjusted electrical stimulation signal based on feedback received from the patient, wherein the adjusted electrical stimulation signal includes a plurality of local maxima and a plurality of local minima, and delivering the adjusted electrical stimulation signal through the electrodes to provide electrical stimulation therapy to the patient.Type: GrantFiled: December 5, 2022Date of Patent: March 12, 2024Assignee: Soin Neuroscience, LLCInventors: Eric A. Schepis, Amol Soin
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Patent number: 11903633Abstract: The present invention is directed to a system and method for adaptive multivariate control for performing a radiofrequency (RF) ablation procedure with an energy delivery device. The system includes an energy source for delivering energy to a patient's body; one or more energy delivery devices; two or more sensors for measuring at least two factors related to an ablation procedure, respectively; and at least one processor.Type: GrantFiled: December 30, 2020Date of Patent: February 20, 2024Assignee: Avent, Inc.Inventors: Eric A. Schepis, Ryan B. Caldwell, Jalpa S. Shah, Lee C. Burnes, Amol Soin
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Patent number: 11793443Abstract: A method of providing therapy to a patient according to one embodiment includes partitioning a frequency range into a plurality of discrete frequency bands with each having a corresponding bandwidth, generating a composite electrical signal based on a plurality of periodic signals, wherein each periodic signal has a frequency within a corresponding frequency band of the plurality of discrete frequency bands, delivering the composite electrical signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or a current of the composite electrical signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.Type: GrantFiled: November 9, 2022Date of Patent: October 24, 2023Assignee: Soin Neuroscience, LLCInventors: Eric A Schepis, Amol Soin
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Patent number: 11766559Abstract: A method of providing therapy to a patient according to one embodiment includes generating an electrical noise signal by at least one noise generator controlled by a controller of a tunable noise system, partitioning the electrical noise signal into a plurality of discrete frequency bands, each of the discrete frequency bands having a corresponding bandwidth, delivering the electrical noise signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or current of the electrical noise signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted electrical signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.Type: GrantFiled: December 8, 2021Date of Patent: September 26, 2023Assignee: Soin Neuroscience, LLCInventors: Eric A. Schepis, Amol Soin
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Publication number: 20230240580Abstract: A method of providing therapy to a patient according to one embodiment includes partitioning a frequency range into a plurality of discrete frequency bands with each having a corresponding bandwidth, generating a composite electrical signal based on a plurality of periodic signals, wherein each periodic signal has a frequency within a corresponding frequency band of the plurality of discrete frequency bands, delivering the composite electrical signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or a current of the composite electrical signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.Type: ApplicationFiled: November 9, 2022Publication date: August 3, 2023Inventors: Eric A. Schepis, Amol Soin
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Publication number: 20230158304Abstract: A method of providing electrical stimulation therapy to a patient according to one embodiment includes generating an un-tuned electrical noise signal by at least one noise generator, partitioning the un-tuned electrical noise signal into a plurality of discrete frequency bands having corresponding bandwidths, delivering the un-tuned electrical noise signal through one or more electrodes to the patient to target the patient's central or peripheral nervous system, adjusting, for each of a plurality of selected frequency bands, an amplitude of the voltage or current of the un-tuned electrical noise signal within a corresponding frequency band to generate an adjusted electrical stimulation signal based on feedback received from the patient, wherein the adjusted electrical stimulation signal includes a plurality of local maxima and a plurality of local minima, and delivering the adjusted electrical stimulation signal through the electrodes to provide electrical stimulation therapy to the patient.Type: ApplicationFiled: December 5, 2022Publication date: May 25, 2023Inventors: Eric A. Schepis, Amol Soin
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Publication number: 20230012663Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.Type: ApplicationFiled: September 19, 2022Publication date: January 19, 2023Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
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Patent number: 11446498Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.Type: GrantFiled: November 6, 2019Date of Patent: September 20, 2022Assignee: Avent, Inc.Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
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Publication number: 20220202471Abstract: The present invention is directed to a system and method for adaptive multivariate control for performing a radiofrequency (RF) ablation procedure with an energy delivery device. The system includes an energy source for delivering energy to a patient's body; one or more energy delivery devices; two or more sensors for measuring at least two factors related to an ablation procedure, respectively; and at least one processor.Type: ApplicationFiled: December 30, 2020Publication date: June 30, 2022Inventors: Eric A. Schepis, Ryan B. Caldwell, Jalpa S. Shah, Lee C. Burnes, Amol Soin
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Publication number: 20220169508Abstract: The present invention relates to pharmaceutical compositions of nitrites such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The pharmaceutical compositions, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO2?). The pharmaceutical compositions of the invention are useful, for example, for treating or reducing pain, improving symptoms of a microvascular disease, and improving nerve conduction velocity.Type: ApplicationFiled: February 14, 2022Publication date: June 2, 2022Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical CollegeInventors: Amol SOIN, Christopher KEVIL, Kyle CHAN, Anthony GIORDANO
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Publication number: 20220105344Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.Type: ApplicationFiled: December 17, 2021Publication date: April 7, 2022Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
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Publication number: 20220096822Abstract: A method of providing therapy to a patient according to one embodiment includes generating an electrical noise signal by at least one noise generator controlled by a controller of a tunable noise system, partitioning the electrical noise signal into a plurality of discrete frequency bands, each of the discrete frequency bands having a corresponding bandwidth, delivering the electrical noise signal through one or more electrodes to the patient to target at least one of neural tissue or non-neural tissue of the patient, adjusting an amplitude of one or more of a voltage or current of the electrical noise signal within a selected frequency band of the plurality of discrete frequency bands to generate an adjusted electrical signal based on feedback received from the patient, and delivering the adjusted electrical signal through the one or more electrodes to provide therapy to the patient.Type: ApplicationFiled: December 8, 2021Publication date: March 31, 2022Inventors: Eric A. Schepis, Amol Soin
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Patent number: 11247902Abstract: The present invention relates to pharmaceutical compositions of nitrites such as inorganic nitrites, or any pharmaceutically acceptable salts, solvates, or prodrugs thereof, and the medical use of these compositions. The pharmaceutical compositions, which can be formulated for oral administration, can provide immediate release or extended release of the nitrite ion (NO2?). The pharmaceutical compositions of the invention are useful, for example, for treating or reducing pain, improving symptoms of a microvascular disease, and improving nerve conduction velocity.Type: GrantFiled: June 6, 2017Date of Patent: February 15, 2022Inventors: Amol Soin, Christopher Kevil, Kyle Chan, Anthony Giordano
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Patent number: 11202909Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.Type: GrantFiled: November 9, 2020Date of Patent: December 21, 2021Assignee: Avent, Inc.Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
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Publication number: 20210052899Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.Type: ApplicationFiled: November 9, 2020Publication date: February 25, 2021Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
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Patent number: 10828491Abstract: The present disclosure is directed to a system and method for selectively and reversibly modulating targeted neural and non-neural tissue of a nervous system for the treatment of pain. An electrical stimulation is delivered to the treatment site that selectively and reversibly modulates the targeted neural- and non-neural tissue of the nervous structure, inhibiting pain while preserving other sensory and motor function, and proprioception.Type: GrantFiled: November 6, 2019Date of Patent: November 10, 2020Assignee: Avent, Inc.Inventors: Eric A. Schepis, David M. Page, Phillip A. Schorr, Shyamy R. Sastry, Leah Roldan, Natalia Alexeeva, Ryan Caldwell, Amol Soin
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Patent number: 10792496Abstract: The exemplified systems and methods facilitate a nerve conduction block at a target nerve using electrical stimulation applied from one or more electrodes located on a percutaneous lead that are placed in parallel, or substantially in parallel, and without direct contact, to a long axis of the peripheral nerve over an overlapping nerve region of greater than about 3 millimeters. The exemplified system and method can be further configured to block nerve condition without eliciting onset activity and co-excitation of non-targeted structures. The exemplified method and system can be performed using conventional percutaneous leads, though an improved percutaneous lead design is disclosed herein. In an aspect, an introducer is disclosed that facilitates accurate and consistent insertion of the percutaneous lead to the specified or intended position relative to the target nerve. In another aspect, a treatment kit comprising the various system components to treat pain is disclosed.Type: GrantFiled: March 15, 2019Date of Patent: October 6, 2020Assignee: Avent, Inc.Inventors: Eric A. Schepis, Phillip A. Schorr, Shyamy R. Sastry, Ryan Caldwell, David M. Page, Amol Soin
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Patent number: 10780270Abstract: The exemplified systems and methods facilitate a nerve conduction block at a target nerve using electrical stimulation applied from one or more electrodes located on a percutaneous lead that are placed in parallel, or substantially in parallel, and without direct contact, to a long axis of the peripheral nerve over an overlapping nerve region of greater than about 3 millimeters. The exemplified system and method can be further configured to block nerve condition without eliciting onset activity and co-excitation of non-targeted structures. The exemplified method and system can be performed using conventional percutaneous leads, though an improved percutaneous lead design is disclosed herein. In an aspect, an introducer is disclosed that facilitates accurate and consistent insertion of the percutaneous lead to the specified or intended position relative to the target nerve. In another aspect, a treatment kit comprising the various system components to treat pain is disclosed.Type: GrantFiled: March 15, 2019Date of Patent: September 22, 2020Assignee: Avent, Inc.Inventors: Eric A. Schepis, Phillip A. Schorr, Wanzhan Liu, Natalia Alexeeva, Shyamant R. Sastry, Amol Soin, David M. Page, Ryan Caldwell