Patents by Inventor Amram Samuni

Amram Samuni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitroxide radicals for the treatment of diseases of the respiratory tract
    Patent number: 10441568
    Abstract: Cyclic nitroxide compounds including, but not limited to, compounds having the general formula I: wherein the dashed line and R1-R8 are as defined herein, are disclosed herein for use in treating diseases and disorders of the respiratory tract and/or respiratory tract remodeling.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: October 15, 2019
    Assignees: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Hadasit Medical Research Services and Development Ltd.
    Inventors: Sara Goldstein, Amram Samuni, Neville Berkman
  • NITROXIDE RADICALS FOR THE TREATMENT OF DISEASES OF THE RESPIRATORY TRACT
    Publication number: 20180085347
    Abstract: Cyclic nitroxide compounds including, but not limited to, compounds having the general formula I: wherein the dashed line and R1-R8 are as defined herein, are disclosed herein for use in treating diseases and disorders of the respiratory tract and/or respiratory tract remodeling.
    Type: Application
    Filed: March 24, 2016
    Publication date: March 29, 2018
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem, Hadasit Medical Research Services and Development Ltd.
    Inventors: Sara GOLDSTEIN, Amram SAMUNI, Neville BERKMAN
  • Nitroxides as protectors against oxidative stress
    Patent number: 5462946
    Abstract: The instant invention is directed to the use of a biologically compatible composition, containing an effective amount of a metal independent nitroxide compound which is preferably represented by the formula ##STR1## wherein R.sub.1 is --CH.sub.3 ; R.sub.2 is --C.sub.2 H.sub.5, --C.sub.3 H.sub.7, --C.sub.4 H.sub.9, --C.sub.5 H.sub.11, --C.sub.6 H.sub.13, --CH.sub.2 --CH(CH.sub.3).sub.2, --CHCH.sub.3 C.sub.2 H.sub.5, or --(CH.sub.2).sub.7 --CH.sub.3, or wherein R.sub.1 and R.sub.2 together form spirocyclopentane, spirocyclohexane, spirocycloheptane, spirocyclooctane, 5-cholestane, or norbornane, R.sub.3 is --O. or --OH, or a physiologically acceptable salt thereof, and a pharmaceutically acceptable carrier, as antioxidants capable of protecting cells, tissues, organs, and whole organisms against the deleterious effects of harmful oxygen-derived species generated during oxidative stress.
    Type: Grant
    Filed: March 20, 1992
    Date of Patent: October 31, 1995
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: James B. Mitchell, Amram Samuni, William DeGraff, Stephen Hahn