Patents by Inventor Amy Chuong

Amy Chuong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Red-shifted opsin molecules and uses thereof
    Patent number: 10106584
    Abstract: Compositions and methods for altering cell activity and function by expressing a light-activated ion pump polypeptide in a cell and contacting the cell with light that activates the expressed light-activated ion pump polypeptide. In some aspects of the invention, a light-activated ion pump polypeptide is a modified haloarcula halorhodopsin polypeptide, for example, a modified Halo 57 polypeptide.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: October 23, 2018
    Assignee: Massachusetts Institute of Technology
    Inventors: Amy Chuong, Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Xue Han
  • RED-SHIFTED OPSIN MOLECULES AND USES THEREOF
    Publication number: 20170044219
    Abstract: Compositions and methods for altering cell activity and function by expressing a light-activated ion pump polypeptide in a cell and contacting the cell with light that activates the expressed light-activated ion pump polypeptide. In some aspects of the invention, a light-activated ion pump polypeptide is a modified haloarcula halorhodopsin polypeptide, for example, a modified Halo 57 polypeptide.
    Type: Application
    Filed: September 30, 2016
    Publication date: February 16, 2017
    Applicant: Massachusetts Institute of Technology
    Inventors: Amy Chuong, Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Xue Han
  • Red-shifted opsin molecules and uses thereof
    Patent number: 9500641
    Abstract: Compositions and methods for altering cell activity and function by expressing a light-activated ion pump polypeptide in a cell and contacting the cell with light that activates the expressed light-activated ion pump polypeptide. In some aspects of the invention, a light-activated ion pump polypeptide is a modified haloarcula halorhodopsin polypeptide, for example, a modified Halo 57 polypeptide.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: November 22, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Amy Chuong, Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Xue Han
  • RED-SHIFTED OPSIN MOLECULES AND USES THEREOF
    Publication number: 20150192567
    Abstract: The invention, in some aspects relates to compositions and methods for altering cell activity and function and the use of light-activated ion pumps (LAIPs).
    Type: Application
    Filed: January 20, 2015
    Publication date: July 9, 2015
    Inventors: Amy Chuong, Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Xue Han
  • Red-shifted opsin molecules and uses thereof
    Patent number: 8957028
    Abstract: The invention, in some aspects, relates to compositions and methods for altering cell activity and function. The invention also relates, in part, to the use of light-activated ion pumps (LAIPs) such as a light-activated ion pump polypeptide that when expressed in an excitable cell and contacted with a red light silences the excitable cell, wherein the polypeptide sequence of the light-activated ion pump comprises a wild-type or modified halomicrobium or haloarcula halorhodopsin polypeptide sequence.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: February 17, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Amy Chuong, Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Xue Han
  • LIGHT-ACTIVATED ION CHANNEL MOLECULES AND USES THEREOF
    Publication number: 20120214188
    Abstract: The invention, in some aspects relates to compositions and methods for altering cell activity and function and the use of light-activated ion channels (LAICs).
    Type: Application
    Filed: November 14, 2011
    Publication date: August 23, 2012
    Inventors: Nathan Klapoetke, Amy Chuong, Brian Yichiun Chow, Edward Boyden, Xue Han, Gane Ka-Shu Wong
  • RED-SHIFTED OPSIN MOLECULES AND USES THEREOF
    Publication number: 20120121542
    Abstract: The invention, in some aspects relates to compositions and methods for altering cell activity and function and the use of light-activated ion pumps (LAIPs).
    Type: Application
    Filed: November 14, 2011
    Publication date: May 17, 2012
    Inventors: Amy Chuong, Nathan Klapoetke, Brian Yichiun Chow, Edward Boyden, Xue Han