Patents by Inventor Amy Elder

Amy Elder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20170342054
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: January 5, 2017
    Publication date: November 30, 2017
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard P. Sard, Yiliang Zhang, Douglas Wilson
  • THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20170217923
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Application
    Filed: March 13, 2017
    Publication date: August 3, 2017
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • Therapeutic compounds and related methods of use
    Patent number: 9630947
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP), such as those of formula (III), and composition thereof are described herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: April 25, 2017
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20150307477
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 29, 2015
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20150284365
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: November 4, 2014
    Publication date: October 8, 2015
    Applicant: GALENEA CORPORATION
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard P. Sard, Yiliang Zhang, Douglas Wilson
  • Therapeutic compounds and related methods of use
    Patent number: 9073890
    Abstract: Compounds, pharmaceutical compositions containing the compounds, and methods of using the compounds to treat a disorder, e.g., schizophrenia and cognitive deficit, in a subject are described herein. The compounds disclosed herein include quinoline and quinazoline-containing compounds that modulate striatal-enriched tyrosine phosphatase (STEP) activity.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: July 7, 2015
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • Compounds and methods of use thereof
    Patent number: 8912220
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: December 16, 2014
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard Sard, Yiliang Zhang, Doug Wilson
  • QUINAZOLINES AS THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20140315886
    Abstract: Methods of treating disorders using compounds (I) that modulate stri-atal-enriched tyrosine phosphatase (STEP) are described herein. Exemplary disorders include schizophrenia and cognitive deficit. Formula (I).
    Type: Application
    Filed: June 28, 2012
    Publication date: October 23, 2014
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahahi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimiza, Kevin J. Hodgetts, Jason S. Newcom
  • THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20130053341
    Abstract: Methods of treating disorders using compounds that modulate striatal-enriched tyrosine phosphatase (STEP) are de-scribed herein. Exemplary disorders include schizophrenia and cognitive deficit.
    Type: Application
    Filed: December 30, 2010
    Publication date: February 28, 2013
    Inventors: Masaki Suzuki, Kazumi Kondo, Muneaki Kurimura, Krishna Reddy Valluru, Akira Takahashi, Takeshi Kuroda, Haruka Takahashi, Tae Fukushima, Shin Miyamura, Indranath Ghosh, Abhishek Dogra, Geraldine Harriman, Amy Elder, Satoshi Shimizu, Kevin J. Hodgetts, Jason S. Newcom
  • THIOLACTAMS AND USES THEREOF
    Publication number: 20120309743
    Abstract: This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
    Type: Application
    Filed: August 9, 2012
    Publication date: December 6, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Indu T. Bharathan, Matthew Duffey, Amy Elder, Jianping Guo, Gang Li, Dominic Reynolds, Francois Soucy, Tricia J. Vos
  • THIOLACTAMS AND USES THEREOF
    Publication number: 20120302551
    Abstract: This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
    Type: Application
    Filed: August 9, 2012
    Publication date: November 29, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Indu T. Bharathan, Matthew Duffey, Amy Elder, Jianping Guo, Gang Li, Dominic Reynolds, Francois Soucy, Tricia J. Vos
  • Thiolactams and uses thereof
    Patent number: 8268992
    Abstract: This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: September 18, 2012
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Indu T. Bharathan, Matthew Duffey, Amy Elder, Jianping Guo, Gang Li, Dominic Reynolds, Francois Soucy, Tricia J. Vos
  • THIOLACTAMS AND USES THEREOF
    Publication number: 20110257157
    Abstract: This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
    Type: Application
    Filed: June 30, 2011
    Publication date: October 20, 2011
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Indu T. Bharathan, Matthew Duffey, Amy Elder, Jianping Guo, Gang Li, Dominic Reynolds, Francois Soucy, Tricia J. Vos
  • Thiolactams and uses thereof
    Patent number: 7998952
    Abstract: This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
    Type: Grant
    Filed: December 4, 2009
    Date of Patent: August 16, 2011
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Indu T. Bharathan, Matthew Duffey, Amy Elder, Jianping Guo, Gang Li, Dominic Reynolds, Francois Soucy, Tricia J. Vos
  • COMPOUNDS AND METHODS OF USE THEREOF
    Publication number: 20110144090
    Abstract: Indole compounds are disclosed. Also disclosed are methods for using the compounds to treat human and animal disease, pharmaceutical compositions of the compounds, and kits including the compounds.
    Type: Application
    Filed: August 10, 2010
    Publication date: June 16, 2011
    Inventors: Amy Elder, Geraldine Harriman, Silvana Leit, Jie Li, Howard Sard, Yiliang Zhang, Doug Wilson
  • THIOLACTAMS AND USES THEREOF
    Publication number: 20100179126
    Abstract: This invention provides compounds of formula I: wherein R1, R2, R3, R4, R5, and R6 are as described in the specification. The compounds are inhibitors of PLK and are thus useful for treating proliferative, inflammatory, or cardiovascular disorders.
    Type: Application
    Filed: December 4, 2009
    Publication date: July 15, 2010
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Indu T. Bharathan, Matthew Duffey, Amy Elder, Jianping Guo, Gang Li, Dominic Reynolds, Francois Soucy, Tricia J. Vos
  • Chemokine receptor antagonists and methods of use therefor
    Publication number: 20070060592
    Abstract: Disclosed are novel compounds and a method of treating a disease associated with aberrant leukocyte recruitment and/or activation. The method comprises administering to a subject in need an effective amount of a compound represented by: or physiologically acceptable salt thereof.
    Type: Application
    Filed: November 10, 2006
    Publication date: March 15, 2007
    Inventors: Jay Luly, Yoshisuke Nakasato, Etsuo Ohshima, Geraldine Harriman, Kenneth Carson, Shomir Ghosh, Amy Elder, Karen Mattia
  • PGD2 receptor antagonists for the treatment of inflammatory diseases
    Publication number: 20060241109
    Abstract: Disclosed are CRTH2 inhibitors represented by Structural Formula (I): The values for the variables of Structural Formula (I) are provided herein.
    Type: Application
    Filed: February 23, 2006
    Publication date: October 26, 2006
    Inventors: Jeremy Little, Shomir Ghosh, Sean Harrison, Amy Elder, Christelle Renou, Kenneth Carson
  • PGD2 receptor antagonists for the treatment of inflammatory diseases
    Publication number: 20060106061
    Abstract: Disclosed herein are compounds represented by Structural Formula (I): (I), wherein the variables are defined herein. Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2 (“CRTH2”) for the treatment of inflammatory disorders.
    Type: Application
    Filed: December 20, 2005
    Publication date: May 18, 2006
    Inventors: Shomir Ghosh, Amy Elder, Kenneth Carson, Kevin Sprott, Sean Harrison
  • PGD2 receptor antagonists for the treatment of inflammatory diseases
    Publication number: 20050256158
    Abstract: Disclosed herein are compounds represented by Structural Formula (I) and (I-A): Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2, or simply “CRTH2” for the treatment of inflammatory disorders. The variables in Structural Formula (I) and (I-A) are defined herein.
    Type: Application
    Filed: April 7, 2005
    Publication date: November 17, 2005
    Inventors: Shomir Ghosh, Amy Elder, Kenneth Carson, Kevin Sprott, Sean Harrison, Frederick Hicks, Christelle Renou, Dominic Reynolds