Patents by Inventor Amy Johnson

Amy Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MONOLITHIC SPACE TELESCOPES AND MOUNTING SYSTEM
    Publication number: 20240160003
    Abstract: Disclosed are methods and devices related to a radial mounting interface holding a compact monolithic telescope, or generally an optical component, with robust optical alignment. An example optical mounting apparatus includes a mounting structure including a plurality of segments that are configured to surround a circumferential area of a monolithic optical device and to hold the monolithic optical device in place, wherein each of the plurality of segments includes a ridged or a grooved interface surface to couple the mounting structure to corresponding grooves or ridges in a surface of the monolithic optical device. The apparatus further includes an elastomeric material confined between the ridged or grooved interface surface of the mounting structure and the one or more corresponding grooves or ridges in the surface of the monolithic optical device. Also disclosed are thermal management features that passively enable diffraction-limited performance of large aperture monolithic optics.
    Type: Application
    Filed: November 10, 2023
    Publication date: May 16, 2024
    Inventors: Frank Ravizza, Brian J. Bauman, Tiffany Yslas, Lisle B. Hagler, Amy Wat, Jonathan Michael Gordon, Michael Yiu-Ming Wong, Alexander J. Pertica, Hilary Johnson, Jordan Smilo
  • ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
    Publication number: 20230357357
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Application
    Filed: June 26, 2023
    Publication date: November 9, 2023
    Inventors: Shunhai Wang, Ning Li, Hunter Chen, Amardeep Singh Bhupender Bhalla, Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Grapel
  • BIOREACTOR FOR ANTIBODY PRODUCTION
    Publication number: 20230332084
    Abstract: The present invention pertains to methods for manufacturing high titer antibody products. In particular, the invention pertains, in part, to improved serum-free animal cell culture medium, which can used for the production of a protein of interest. Additionally, the present invention further pertains to chromatographic procedures employed to successfully isolate the antibody product subject of the present disclosure.
    Type: Application
    Filed: February 28, 2023
    Publication date: October 19, 2023
    Inventors: John Mattila, Xiaolin Tang, Hanne Bak, Shawn M. Lawrence, Amy Johnson, Meghan Casey, Michelle LaFond, Andrew Tustian, Philip Mellors, John Hourihan, John Crowley, Laura Callinan, Shadia Abike Oshodi, Ashley Witmer, Daniel Corbett, James Reilly, Ankit Vartak, Mark Chiboroski, Alessandra Starling, Robert Stairs, Hai-Yuan Goh, Liam Nicholl, Aishling Conlon
  • Anti-VEGF protein compositions and methods for producing the same
    Patent number: 11732025
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Grant
    Filed: November 25, 2022
    Date of Patent: August 22, 2023
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Shunhai Wang, Ning Li, Hunter Chen, Amardeep Singh Bhupender Bhalla, Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Grapel
  • ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
    Publication number: 20230119662
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Application
    Filed: November 25, 2022
    Publication date: April 20, 2023
    Inventors: Shunhai Wang, Ning Li, Hunter Chen, Amardeep Singh Bhupender Bhalla, Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Grapel
  • VEGF MINI-TRAPS AND METHOD OF USE THEREOF
    Publication number: 20230063116
    Abstract: The present invention provides VEGF mini-trap molecules and method of treating or preventing angiogenic disorders such as angiogenic eye disorders and cancer.
    Type: Application
    Filed: December 4, 2020
    Publication date: March 2, 2023
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: Joel MARTIN, Samuel DAVIS, Shawn LAWRENCE, Amy JOHNSON, Meghan CASEY, Jaimie MASTROGIACOMO, Shunhai WANG, Ning LI, Andrew TUSTIAN, Ankit VARTAK, Matthew FRANKLIN
  • ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
    Publication number: 20230068199
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins.
    Type: Application
    Filed: July 6, 2022
    Publication date: March 2, 2023
    Inventors: Shunhai Wang, Ning Li, Hunter Chen, Amardeep Singh Bhupender Bhalla, Shawn Lawrence, Amy Johnson, Meghan Casey, Jamie Mastrogiacomo
  • Anti-VEGF protein compositions and methods for producing the same
    Patent number: 11548932
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: January 10, 2023
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Shunhai Wang, Ning Li, Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Grapel, Hunter Chen, Amardeep Singh Bhupender Bhalla
  • Methods for producing aflibercept in chemically defined media having reduced aflibercept variants
    Patent number: 11535663
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: December 27, 2022
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Mastrogiacomo, Shunhai Wang, Ning Li
  • ANTI-VEGF PROTEIN COMPOSITIONS AND METHODS FOR PRODUCING THE SAME
    Publication number: 20220389081
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Application
    Filed: June 15, 2022
    Publication date: December 8, 2022
    Inventors: Shunhai Wang, Ning Li, Shawn Lawrence, Amy Johnson, Meghan Casey, Jamie Mastrogiacomo, Hunter Chen, Amardeep Singh Bhupender Bhalla
  • Anti-VEGF protein compositions and methods for producing the same
    Patent number: 11505594
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Grant
    Filed: April 1, 2022
    Date of Patent: November 22, 2022
    Assignee: Regeneran Pharmaceuticals, Inc.
    Inventors: Andrew Tustian, Ankit Vartak, Thomas Daly, Erica Pyles, Nisha Palackal, Shunhai Wang, Ning Li, Matthew Franklin, Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Grapel
  • Methods for producing aflibercept in chemically defined media having reduced aflibercept variants
    Patent number: 11472861
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: October 18, 2022
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Mastrogiacomo, Shunhai Wang, Ning Li
  • METHODS FOR PRODUCING AFLIBERCEPT IN CHEMICALLY DEFINED MEDIA HAVING REDUCED AFLIBERCEPT VARIANTS
    Publication number: 20220127331
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 28, 2022
    Inventors: Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Mastrogiacomo, Shunhai Wang, Ning Li
  • METHODS FOR PRODUCING AFLIBERCEPT IN CHEMICALLY DEFINED MEDIA HAVING REDUCED AFLIBERCEPT VARIANTS
    Publication number: 20220033471
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Application
    Filed: July 22, 2021
    Publication date: February 3, 2022
    Inventors: Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Mastrogiacomo, Shunhai Wang, Ning Li
  • CELL CULTURE PROCESS FOR MAKING A GLYCOPROTEIN
    Publication number: 20210388408
    Abstract: The instant application provides a method for screening batches of soy hydrolysate for a desired amount of a component thereof, such as ornithine or putrescine, and selecting only those batches of soy hydrolysate that have a desired amount of such component. The present disclosure also sets forth methods for culturing cells in media supplemented with selected batches of soy to produce more consistent, high quality lots of a protein of interest. Further, the present disclosure provides a plurality of protein preparations that have each been produced by culturing cells in media supplemented with separate batches of soy hydrolysate containing a desired amount of ornithine or putrescine, whereby each batch of protein produced exhibits improved quality of the protein of interest or amount of quality protein produced.
    Type: Application
    Filed: August 23, 2021
    Publication date: December 16, 2021
    Inventors: John CHEN, Shawn LAWRENCE, Amy JOHNSON, Theodore LONEY, Ravindra PANGULE, Ta-Chun HANG, Scott CARVER, Bernhard SCHILLING
  • CELL CULTURE PROCESS FOR MAKING A GLYCOPROTEIN
    Publication number: 20210388407
    Abstract: The instant application provides a method for screening batches of soy hydrolysate for a desired amount of a component thereof, such as ornithine or putrescine, and selecting only those batches of soy hydrolysate that have a desired amount of such component. The present disclosure also sets forth methods for culturing cells in media supplemented with selected batches of soy to produce more consistent, high quality lots of a protein of interest. Further, the present disclosure provides a plurality of protein preparations that have each been produced by culturing cells in media supplemented with separate batches of soy hydrolysate containing a desired amount of ornithine or putrescine, whereby each batch of protein produced exhibits improved quality of the protein of interest or amount of quality protein produced.
    Type: Application
    Filed: August 23, 2021
    Publication date: December 16, 2021
    Inventors: John CHEN, Shawn LAWRENCE, Amy JOHNSON, Theodore LONEY, Ravindra PANGULE, Ta-Chun HANG, Scott CARVER, Bernhard SCHILLING
  • Methods for producing aflibercept in chemically defined media having reduced aflibercept variants
    Patent number: 11104715
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: August 31, 2021
    Assignee: Regeneran Pharmaceuticals, Inc.
    Inventors: Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Mastrogiacomo, Shunhai Wang, Ning Li
  • METHODS FOR PRODUCING AFLIBERCEPT IN CHEMICALLY DEFINED MEDIA HAVING REDUCED AFLIBERCEPT VARIANTS
    Publication number: 20210206832
    Abstract: The present disclosure pertains to compositions comprising anti-VEGF proteins and methods for producing such compositions.
    Type: Application
    Filed: August 18, 2020
    Publication date: July 8, 2021
    Inventors: Shawn Lawrence, Amy Johnson, Meghan Casey, Jaimie Mastrogiacomo, Shunhai Wang, Ning Li
  • CELL CULTURE PROCESS FOR MAKING A GLYCOPROTEIN
    Publication number: 20200255880
    Abstract: The instant application provides a method for screening batches of soy hydrolysate for a desired amount of a component thereof, such as ornithine or putrescine, and selecting only those batches of soy hydrolysate that have a desired amount of such component. The present disclosure also sets forth methods for culturing cells in media supplemented with selected batches of soy to produce more consistent, high quality lots of a protein of interest. Further, the present disclosure provides a plurality of protein preparations that have each been produced by culturing cells in media supplemented with separate batches of soy hydrolysate containing a desired amount of ornithine or putrescine, whereby each batch of protein produced exhibits improved quality of the protein of interest or amount of quality protein produced.
    Type: Application
    Filed: May 1, 2020
    Publication date: August 13, 2020
    Inventors: John CHEN, Shawn M. LAWRENCE, Amy JOHNSON, Theodore LONEY, Ravindra PANGULE, Ta-Chun HANG, Scott CARVER, Bernhard SCHILLING
  • CELL CULTURE PROCESS FOR MAKING A GLYCOPROTEIN
    Publication number: 20200131554
    Abstract: The instant application provides a method for screening batches of soy hydrolysate for a desired amount of a component thereof, such as ornithine or putrescine, and selecting only those batches of soy hydrolysate that have a desired amount of such component. The present disclosure also sets forth methods for culturing cells in media supplemented with selected batches of soy to produce more consistent, high quality lots of a protein of interest. Further, the present disclosure provides a plurality of protein preparations that have each been produced by culturing cells in media supplemented with separate batches of soy hydrolysate containing a desired amount of ornithine or putrescine, whereby each batch of protein produced exhibits improved quality of the protein of interest or amount of quality protein produced.
    Type: Application
    Filed: January 14, 2020
    Publication date: April 30, 2020
    Inventors: John CHEN, Shawn LAWRENCE, Amy JOHNSON, Theodore LONEY, Ravindra PANGULE, Ta-Chun HANG, Scott CARVER, Bernhard SCHILLING