Patents by Inventor Amy L. Himmelberger

Amy L. Himmelberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
    Publication number: 20040110717
    Abstract: The present invention provides nucleoside derivatives which are inhibitors of RNA-dependent RNA viral polymerase. These compounds are inhibitors of RNA-dependent RNA viral replication and are useful for the treatment of RNA-dependent RNA viral infection. They are particularly useful as inhibitors of hepatitis C virus (HCV) NS5B polymerase, as inhibitors of HCV replication, and/or for the treatment of hepatitis C infection. The invention also describes pharmaceutical compositions containing such nucleoside derivatives alone or in combination with other agents active against RNA-dependent RNA viral infection, in particular HCV infection. Also disclosed are methods of inhibiting RNA-dependent RNA polymerase, inhibiting RNA-dependent RNA viral replication, and/or treating RNA-dependent RNA viral infection with the nucleoside derivatives of the present invention.
    Type: Application
    Filed: January 16, 2004
    Publication date: June 10, 2004
    Inventors: Steven S. Carroll, Robert L. LaFemina, Dawn L. Hall, Amy L. Himmelberger, Lawrence C. Kuo, David B. Olsen, Carrie A. Rutkowski, Joanne E. Tomassini, Malcolm MacCoss, Haoyun An, Balkrishen Bhat, Neelima Bhat, Phillip Dan Cook, Anne B. Eldrup, Thazha P. Prakash, Marija Prhavc, Charles J. Guinosso