Abstract: A focus card evokes a neurological response in a user to dampen the user's response to a negative stimulus. A focus card has a first face comprising visual graphics such as lenticular graphics, and a second face comprising indicia pertaining to the visual graphics. Indicia are configured for a target population, and can include novel questions, tasks or directions. A parent or other untrained individual can direct a patient as indicated by the indicia. A single focus card can have indicia for several target populations. A focus card can be used in combination with an analgesia means to further reduce a patient's pain response. By focusing the patient's attention with a focus card, behavior of the patient's anterior cingulate gyrus can be modified to reduce the patient's response to a pain-causing stimulus. It can also be used to reduce agitation, anxiety or distress outside of a medical environment.