Patents by Inventor Amy Rasley

Amy Rasley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antigenic combinations against bacteria and related nanolipoprotein particles, compositions, methods and systems
    Patent number: 11491215
    Abstract: Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: November 8, 2022
    Assignees: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC, REGENTS OF THE UNIVERSITY OF NEW MEXICO
    Inventors: Nicholas Fischer, Amy Rasley, Terry Wu, Julie Lovchik
  • MOMP TELONANOPARTICLES, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20220211866
    Abstract: A telodendrimer-nanolipoprotein particle (t-NLP), comprising one or more membrane forming lipids, one or more telodendrimers, and a scaffold protein and a Chlamydia major outer membrane protein (MOMP) comprising a MOMP hydrophobic region, and related compositions methods and systems.
    Type: Application
    Filed: December 23, 2021
    Publication date: July 7, 2022
    Inventors: Matthew A. COLEMAN, Nicholas O. FISCHER, Amy RASLEY, Craig D. BLANCHETTE, Todd PETERSON
  • MOMP telonanoparticles, and related compositions, methods and systems
    Patent number: 11207422
    Abstract: A telodendrimer-nanolipoprotein particle (t-NLP), comprising one or more membrane forming lipids, one or more telodendrimers, and a scaffold protein and a Chlamydia major outer membrane protein (MOMP) comprising a MOMP hydrophobic region, and related compositions methods and systems.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: December 28, 2021
    Assignee: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventors: Matthew A. Coleman, Nicholas O. Fischer, Amy Rasley, Craig D. Blanchette, Todd Peterson
  • ANTIGENIC COMBINATIONS AGAINST FRANCISELLA BACTERIA AND RELATED NANOLIPOPROTEIN PARTICLES, COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20200108133
    Abstract: Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
    Type: Application
    Filed: August 16, 2019
    Publication date: April 9, 2020
    Inventors: Nicholas Fischer, Amy Rasley, Terry Wu, Julie Lovchik
  • MOMP TELONANOPARTICLES, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS
    Publication number: 20200046848
    Abstract: A telodendrimer-nanolipoprotein particle (t-NLP), comprising one or more membrane forming lipids, one or more telodendrimers, and a scaffold protein and a Chlamydia major outer membrane protein (MOMP) comprising a MOMP hydrophobic region, and related compositions methods and systems.
    Type: Application
    Filed: May 1, 2018
    Publication date: February 13, 2020
    Inventors: Matthew A. COLEMAN, Nicholas O. FISCHER, Amy RASLEY, Craig D. BLANCHETTE, Todd PETERSON
  • STABLE NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS METHODS AND SYSTEMS
    Publication number: 20190142752
    Abstract: Nanolipoprotein particles having at least a scaffold protein component and a membrane lipid component and related compositions, methods and systems are described. The membrane lipid component includes at least one or more membrane forming lipids, one or more polymerized lipids and/or one or more polymerizable lipids.
    Type: Application
    Filed: August 25, 2016
    Publication date: May 16, 2019
    Inventors: Craig D. BLANCHETTE, Nicholas FISCHER, Sean Fitzpatrick GILMORE, Amy RASLEY, Paul HENDERSON
  • NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS METHODS AND SYSTEMS FOR LOADING RNA
    Publication number: 20180318218
    Abstract: Nanolipoprotein particles comprising at least a scaffold protein component and a membrane lipid component and related complexes, compositions, methods and systems are described, in which the membrane lipid component comprises at least one or more membrane forming lipids and one or more cationic lipids.
    Type: Application
    Filed: May 2, 2018
    Publication date: November 8, 2018
    Inventors: Kurt I. Kamrud, Nathaniel S. Wang, Martina Felderman, Bolyn Hubby, Heather D. Gouvis, Nicholas O. Fischer, Matthew A. Coleman, Angela Clare Evans, Wei He, Amy Rasley, Craig D. Blanchette