Abstract: A fracturing device includes a power unit, and the power unit includes a muffling compartment, a turbine engine, and an air intake unit. The air intake unit is communicated with the turbine engine through an intake pipe and configured to provide a combustion-supporting gas to the turbine engine; the air intake unit is at a top of the muffling compartment and the muffling compartment has an accommodation space, the turbine engine is within the accommodation space. A fan is further provided to generate wither positive pressure or negative presser in the muffling compartment to facilitate a cooling of the turbine engine.

Abstract: Defect detection method for a semi-conducting bedding layer of a power cable includes: obtaining a length parameter, a corrugation pitch parameter, radius parameters, and a thickness parameter of a power cable; obtaining a first resistance value between a shield and a corrugated sheath, and calculating a second resistance value of the shield based on the length parameter and the corrugation pitch parameter; calculating a radial resistance value of the semi-conducting bedding layer based on the first resistance value and the second resistance value; determining a contact angle of a critical point of contact between the corrugated sheath and the semi-conducting bedding layer based on the radius parameters and the thickness parameter; calculating volume resistivity of the semi-conducting bedding layer based on the radial resistance value and the contact angle; and comparing the volume resistivity with a preset evaluation parameter to obtain a defect detection result of the semi-conducting bedding layer.

Abstract: The present disclosure relates to a Corynebacterium glutamicum mutant strain having enhanced L-lysine productivity and a method of producing L-lysine using the same. The mutant strain may produce L-lysine in an improved yield compared to the parent strain by increasing or enhancing the expression of a gene encoding aspartate-semialdehyde dehydrogenase therein.

Abstract: A liquid preparation and a method for preparing the liquid preparation are disclosed. The liquid preparation contains a high-concentration L-serine or a pharmaceutically acceptable salt thereof, and shows an excellent stability and safety. The liquid preparation exhibits excellent pharmacological effects and is suitable for preventing or treating a central nervous system disease.

Abstract: Disclosed in the present invention is a nanobody, comprising a heavy chain variable region containing CDR1, CDR2 and/or CDR3, and having the function of recognizing and binding to BCMA. Reference can be made to the text for specific CDR sequences. Also disclosed in the present invention are a BCMA binding molecule, a composition comprising the nanobody or BCMA binding molecule, a BCMA detection agent, and an application of the nanobody, the BCMA binding molecule, or the composition in preparation of a drug for treating a BCMA related disease. The nanobody, BCMA binding molecule, and composition in the present invention can recognize and bind to BCMA, and have potential utility for treatment of BCMA related diseases.

Abstract: This invention is in the field of medicinal chemistry and relates to a new class of cyclic dinucleotide conjugates (e.g., Formula I) which function as tumor-targeted imaging agents, and their use in diagnostic and therapeutic intervention for disorders (e.g., cancer).

Abstract: A visual loop-mediated isothermal amplification (LAMP) method for a rapid test of tobacco includes: extracting a genomic DNA of the tobacco, designing primers, establishing a LAMP reaction system, and optimizing the LAMP reaction system. The present disclosure designs the LAMP primers according to a conserved region of a screened tobacco-specific Ntsp151 genomic sequence, and establishes the LAMP method based on color determination. The present disclosure can rapidly identify flue-cured tobacco leaves, finished cigarettes, and tea cigarettes, and achieves a detection limit of 200 copies per reaction. The test results of the LAMP method for non-tobacco samples are negative, indicating that the LAMP method has high specificity. Compared with the quantitative polymerase chain reaction (qPCR) method, the LAMP method has a coincidence rate of 96.7%, but the LAMP method only needs about 1 h to obtain the results.

Abstract: Disclosed herein are second near-infrared (NIR-II) fluorescent composite and its production method. The method mainly includes the steps of, mixing a gold nanocluster having a plurality of a thiol-based compound on its outer surface and alpha-glycerylphosphorylcholine (alpha-GPC) in a solvent to form a mixture; replacing the solvent with an inert gas; and heating the mixture at a temperature about 100-200° C. in the presence of the inert gas until at least a portion of the gold nanocluster is encapsulated by a capping layer consisting of alpha-GPC, thereby producing the NIR-II fluorescent composite. The thus-produced NIR-II fluorescent composite is characterized by having an emission wavelength covering NIR-II region detectable by specialized camera. Also encompassed in the present disclosure is a method for conducting in vivo bioimaging of a target area in a subject.

Abstract: This disclosure relates to a composition comprising (a) 4,4?-methylene diphenyl diisocyanate (4,4?-MDI), and (b) at least one heterocyclic compound comprising as ring moiety at least one structure of formula (I) as defined in the description. The heterocyclic compound can suppress the formation of 4,4?-MDI dimer and thus prevent the formation of insoluble solids and extend the shelf life of 4,4?-MDI.

Abstract: An invention using vehicle wheels with fan blades as spokes to generate the airflow through the vehicle heat sources to optimize the cooling performance by its self-power.

Abstract: The present disclosure provides an ionic gel film preparation method, a chemical sensor and preparation method thereof, relating to the field of sensor technology. The preparation method of ionic gel film includes: blending a vinyl-free ionic liquid with a vinyl-containing ionic liquid and a specified additive to obtain a homogenous solution, taking a predetermined amount of the homogenous solution and dropping it onto a first substrate equipped with interdigital electrodes, flattening the homogenous solution on the first substrate using a second substrate, curing the flattened homogenous solution on the first substrate using ultraviolet light of a preset wavelength, and curing until the vinyl-containing ionic liquid polymerizes in situ to form an ionic gel film. The preparation method of ionic gel film, chemical sensor, and preparation method thereof of the present disclosure have the advantages of good device consistency, high conductivity, and good sensing performance when using the ionic gel film.

Abstract: A rice white leaf and panicle gene wlp3 is provided. The cDNA sequence of the white leaf and panicle gene wlp3 is shown in SEQ ID NO: 1, and the encoded amino acid sequence of the protein is shown in SEQ ID NO: 2. The rice white leaf and panicle gene wlp3 is applied to rice stress resistance and yield increase. The white leaf and panicle gene wlp3 is configured to improve cold tolerance of plants, enhance photosynthetic rate, increase plant height, leaf albinism at seedling stage, panicle albinism at heading stage, and increase panicle length at low temperature. The present disclosure obtains the rice white leaf and panicle gene wlp3 through screening and mutagenesis, which is related to the stress resistance and chlorophyll synthesis of rice. Therefore, the present disclosure provides a foundation for rice breeding.

Abstract: A method of protein deposition for detecting a protein removal effect, a protein culture solution, and a protein cleaning and testing instrument, including preparing a protein culture solution: mixing a protein and a deionized water to obtain a diluted protein solution and adjusting a PH value of the diluted protein solution, to obtain the protein culture solution; and culturing the corneal contact lens using the protein culture solution: placing the corneal contact lens and the protein culture solution in a culture container for sealed culture within a culture temperature range for a time duration, to obtain a protein deposited corneal contact lens. The method is more suitable to be used as a testing sample of a protein removal effect testing experiment, reducing the difficulty in testing and judging of the degree of fouling of the corneal contact lens and the cleaning effect of the protein removal effect testing experiment.

Abstract: The present invention relates to a crystalline form and/or maleate, phosphate, L-tartrate, and adipate of the compound represented by the structural formula I, and various crystalline forms of various salt forms, and preparation methods and applications thereof.

Abstract: An embodiment of the present application discloses a display panel and a splicing display panel. The display panel includes a display panel main body and a light grating layer. The light grating layer is formed on the display panel main body. The light grating layer includes a plurality of light gratings, and the light gratings are arranged at intervals along a first direction. The light gratings are arranged at intervals along a second direction, and the first direction intersects the second direction.

Abstract: The present invention encompasses compounds of formula (I) wherein R1a, R1b, R2a, R2b, Z, R3 to R5, A, p, U, V and W have the meanings given in the claims and specification, their use as inhibitors of KRAS, pharmaceutical compositions and preparations containing such compounds and their use as medicaments/medical uses, especially as agents for treatment and/or prevention of oncological diseases.

Abstract: A method of chlorinating an antimony fluorohalide catalyst is disclosed. In one embodiment the method comprises contacting an antimony fluorohalide catalyst that contains one or more fluorines with a regenerating agent selected from 2-chloro-3,3,3-trifluoropropene (1233xf), 1,1,1,3-tetrachloropropane (250fb), 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb), and combinations of 1233xf, 250fb, and 244bb, under conditions effective to exchange at least one fluorine in the antimony fluorohalide catalyst with chlorine. The method can be used to regenerate spent antimony fluorohalide catalyst, for example regenerating SbCl5 from SbF5.

Abstract: Provided is a biodegradable polyester polymer comprising a polymerization reaction product of an aliphatic dicarboxylic acid, an C6-30 aromatic dicarboxylic acid, an aliphatic diol, and a branching agent, and wherein the biodegradable polyester polymer has a ratio of z-average molecular weight (Mz) to weight average molecular weight (Mw) (“Mz/Mw”) greater than 2 and an easy-tear film including the same. The biodegradable film has excellent mechanical properties to effectively protect a product inside the packaging but also be easily opened in a controlled manner without excessive force and at the same time, provide an environmentally-friendly alternative to non-degradable plastics.

Abstract: A magnetic resonance scanning method including: detecting the positions of individual characteristic points of interest and the positions and sizes of individual sites of interest of a target human body in the current MR scan; calculating a scan start position and a total scan range of the current MR scan according to the detected positions of the individual characteristic points of interest and the positions and sizes of the individual sites of interest of the target human body; and performing the current MR scan according to the calculated scan start position and total scan range of the MR scan. In an aspect, the scanning method is fully automatic.

Abstract: Skin-core structure fibers with both infrared and radar stealth, a preparation method therefor, and the use thereof are provided. The fibers are as follows: a core material of the skin-core structure fibers comprises the following raw materials in parts by weight: 10 parts of paraffin; 0.7-1.5 parts of an electromagnetic wave absorbent; and 1 part of a high-molecular polymer, wherein the electromagnetic wave absorbent is one or more of ferroferric oxide-intercalated graphene oxide, nano ferroferric oxide and carbon black, and wherein the skin-core structure fiber is obtained by spinning the core material with a skin-layer material.