Abstract: A carton for containing a plurality of containers includes a bottom panel, at least one top panel, at least one side panel, at least one top end flap foldably connected to the at least one top panel, at least one bottom end flap foldably connected to the bottom panel, and at least one side end flap foldably connected to the at least one side panel. The carton further includes a handle including a handle strap separable from the at least one top panel and foldably connected to a relief portion, the relief portion being defined by spaced apart cuts in the at least one top end flap, the relief portion for being positioned in a container gap defined by a nested arrangement of the plurality of containers when the handle is activated.

Abstract: A carrier for holding a plurality of containers can include a plurality of panels including at least one central panel, at least one attachment panel foldably connected to the at least one central panel and configured to receive a portion of one or more containers of the plurality of containers, at least one side panel foldably connected to the at least one attachment panel, and at least one top panel foldably connected to the at least one side panel. The at least one central panel can include a plurality of openings and can be for being positioned between and attached to adjacent containers of the plurality of containers. The at least one top panel can have an outer free edge arranged to expose a portion of the at least one attachment panel.

Abstract: A carrier for holding a plurality of containers includes a plurality of panels having at least one central panel, at least one attachment panel foldably connected to the at least one central panel and configured to receive a portion of at least one container of the plurality of containers, and at least one side panel foldably connected to the at least one attachment panel. The at least one central panel includes a plurality of openings and is positioned between and attached to adjacent containers of the plurality of containers, and the at least one side panel is attached to at least one container of the plurality of containers.

Abstract: A carrier for holding a plurality of containers includes a plurality of panels including at least one central panel and at least one attachment panel foldably connected to the at least one central panel, the at least one attachment panel including container retention features for engaging at least one container of the plurality of containers. The at least one central panel includes a plurality of openings and is for being positioned between and attached to adjacent containers of the plurality of containers.

Abstract: The invention relates to the use of 1-(4,6-dipentyl-5,6-dihydro-2H-1,2,3-oxadiazin-2-yl)-3-hydroxypropan-1-one in treating and/or preventing infections caused by a bacterium, fungus or virus or in treating and/or preventing cancer. Additionally, the invention relates to a process for obtaining the compound of formula (I) of the invention, said process comprising the steps of cultivating a strain of Dolichospermum sp in an aqueous nutrient medium with assimilable carbon and nitrogen sources and salts, under controlled aerobic conditions, and then recovering the compound of general formula (I) from the culture broth.

Abstract: The implantable medical device includes high-voltage components (such as defibrillation shock generation components) operative to generate high-voltage pulses for delivery to tissues of the patient while using the case or housing of the device as a stimulation electrode. The device also includes low-voltage Medical Implant Communication Service (MICS) or Medical Device Radiocommunications Service (MedRadio) components operative to generate low-power signals for communicating with an external device via radio frequencies while using the case as part of an antenna. A conductive noise shield is mounted within the case of the device and interposed between the high-voltage components and the case, with the shield configured to attenuate electrical interference between the high-voltage components and the case to facilitate radio-frequency communication between the low-voltage MICS/MedRadio components and the external device, which use the case as part of the antenna.

Abstract: Devices useful in the delivery of DNA encoding neurotrophic agents, anti-fibrotic agents, and related compositions are disclosed herein for use in the treatment of central and/or peripheral nervous system injury. Methods of making and using the disclosed devices and DNA are also described. In various embodiments, the invention also discloses compositions and devices that may further include a targeting agent, such as a polypeptide that is reactive with an FGF receptor (e.g., bFGF), or another ligand that binds to cell surface receptors on neuronal cells, or a support cell. The invention also discloses methods of promoting neuronal survival and regeneration via transfection of an axon as it grows through a device or composition of the present invention, or via transfection of a repair cell.

Abstract: Devices useful in the delivery of DNA encoding neurotrophic agents, anti-fibrotic agents, and related compositions are disclosed herein for use in the treatment of central and/or peripheral nervous system injury. Methods of making and using the disclosed devices and DNA are also described. In various embodiments, the invention also discloses compositions and devices that may further include a targeting agent, such as a polypeptide that is reactive with an FGF receptor (e.g., bFGF), or another ligand that binds to cell surface receptors on neuronal cells, or a support cell. The invention also discloses methods of promoting neuronal survival and regeneration via transfection of an axon as it grows through a device or composition of the present invention, or via transfection of a repair cell.

Abstract: Devices useful in the delivery of DNA encoding neurotrophic agents, anti-fibrotic agents, and related compositions are disclosed herein for use in the treatment of central and/or peripheral nervous system injury. Methods of making and using the disclosed devices and DNA are also described. In various embodiments, the invention also discloses compositions and devices that may further include a targeting agent, such as a polypeptide that is reactive with an FGF receptor (e.g., bFGF), or another ligand that binds to cell surface receptors on neuronal cells, or a support cell. The invention also discloses methods of promoting neuronal survival and regeneration via transfection of an axon as it grows through a device or composition of the present invention, or via transfection of a repair cell.

Abstract: According to the present invention, processes for detecting the presence of neoplastic disease are provided. The processes involve the detection of a product associated with expression of genes that encode protein receptors for fibroblast growth factor in cells or a product present in a body fluid. Detection can be carried out in a variety of ways, such as by hybridization to detect the presence of mRNA or immunological assays to detect the presence of receptor protein.