Patents by Inventor Ana Maria Henao-Restrepo

Ana Maria Henao-Restrepo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccine nebulisers
    Patent number: 8887713
    Abstract: The invention provides a method of selecting a nebulizer device to be used to deliver a vaccine comprising selecting a nebulizer capable of producing a plurality of vaccine particles having the following particle droplet size distribution: (i) Dv10: 2.0+/?0.2 ?m (ii) Dv50: 5.0+/?0.5 ?m (iii) Dv90: 10.0+/?1.0 ?m (iv) a mean mass aerodynamic diameter (MMAD) of 4.5 to 8.0 ?m This allows the selection of, for example, commercially available nebulizers, previously used for drug delivery, for vaccine delivery. This considerably reduces the work required to identify suitable nebulizers. Nebulizers identified by the methods of the invention are also claimed.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: November 18, 2014
    Assignee: World Health Organization
    Inventors: Felicity Cutts, Jorge Fernandez De Castro, John V. Bennett, Beth Laube, Clyde Witham, Ana Maria Henao-Restrepo, Bernard Cohen, David Brown, John Dennis
  • VACCINE NEBULISERS
    Publication number: 20130032140
    Abstract: The invention provides a method of selecting a nebuliser device to be used to deliver a vaccine comprising selecting a nebuliser capable of producing a plurality of vaccine particles having the following particle droplet size distribution: (i) Dv10: 2.0+/?0.2 ?m (ii) Dv50: 5.0+/?0.5 ?m (iii) Dv90: 10.0+/?1.0 ?m (iv) a mean mass aerodynamic diameter (MMAD) of 4.5 to 8.0 ?m This allows the selection of, for example, commercially available nebulisers, previously used for drug delivery, for vaccine delivery. This considerably reduces the work required to identify suitable nebulisers. Nebulisers identified by the methods of the invention are also claimed.
    Type: Application
    Filed: October 12, 2012
    Publication date: February 7, 2013
    Applicant: World Health Organization
    Inventors: Felicity Cutts, Jorge FERNANDEZ DE CASTRO, John V. BENNETT, Beth LAUBE, Clyde WITHAM, Ana Maria HENAO-RESTREPO, Bernard COHEN, David BROWN, John DENNIS
  • VACCINE NEBULIZERS
    Publication number: 20100074911
    Abstract: The invention provides a method of selecting or optimising a nebuliser device to be used to deliver a vaccine comprising selecting a nebuliser capable of producing a plurality of vaccine particles having the following particle droplet size distribution: (i) Dv10: 2.0+/?0.2 ?m (ii) Dv50: 5.0+/?0.5 ?m (iii) Dv90: 10.0+/?1.0 ?m (iv) a mean mass aerodynamic diameter (MMAD) of 4.5 to 8.0 ?m This allows the selection of, for example, commercially available nebulisers, previously used for drug delivery, for vaccine delivery. This considerably reduces the work required to identify suitable nebulisers. The additional preferred features are disclosed for the selection of nebulisers for use in mass vaccination programs. Nebulisers identified by the methods of the invention are also claimed.
    Type: Application
    Filed: June 27, 2006
    Publication date: March 25, 2010
    Inventors: Felicity Cutts, Jorge Fernandez De Castro, John V. Bennett, Beth Laube, Clyde Witham, Ana Maria Henao-Restrepo, Bernard Cohen, David Brown, John Dennis