Abstract: Certain aspects of the present disclosure provide techniques for Scripting attack detection and mitigation. A method generally includes receiving a first report indicating a first violation for a first security policy applied to a first web application; identifying a first plurality of features associated with the first violation; classifying the first violation as a first JavaScript attack based on the first plurality of features; and taking action to mitigate the first JavaScript attack on the first web application.

Abstract: Described herein are oligonucleotides (e.g., single-stranded oligonucleotides) and compositions thereof for targeting a mutation in the spliceosome, such as the U 1 small nuclear RNA (snRNA), as well as related methods of use.

Abstract: The present disclosure features compounds of formula (1-a) and of formula (II) and pharmaceutical compositions thereof. The present disclosure further discloses the compounds of formula (I-a) and (II) and their compositions for use in methods of modulating nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as said compounds for use in methods of treating e.g.: ?proliferative diseases, such as e.g. cancer, benign neoplasms or angiogenesis, ?neurological diseases or disorders, such as e.g. Huntington's disease, ?autoimmune diseases or disorders, immunodeficiency diseases or disorders, lysosomal storage disease or disorder, cardiovascular diseases or disorders, metabolic diseases or disorders, respiratory diseases or disorders, renal diseases or disorders, or infectious diseases. Exemplary compounds are e.g. 2-(indazol-5-yl)-6-(piperidin-4-yl)-1,7-naphthyridine derivatives and similar compounds.

Abstract: The present disclosure features compounds and related compositions that, inter alia, modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof.

Abstract: The present disclosure features compounds of formula (1-a) and related compositions that, inter alia, modulate nucleic acid splicing e.g., splicing of a pre-mRNA, as well as methods of use thereof.

Abstract: The present disclosure features compounds and related compositions that, inter alia, modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof.

Abstract: The present disclosure features compounds and related compositions that, inter alia, modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof.

Abstract: The present disclosure features compounds and related compositions that, inter alia, modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof.

Abstract: The present disclosure features compounds and related compositions that, inter alia, modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof. Formula (I-b).

Abstract: The present disclosure features compounds and related compositions that, inter alia, modulate nucleic acid splicing, e.g., splicing of a pre-mRNA, as well as methods of use thereof.

Abstract: Systems for vending products to a customer that encompasses a group of co-located vending machines managed by a vending company, a database of current inventory of products in the vending machines and customer purchase history; and the use of a personal electronic device by the customer. Embodiments include a single order by a customer from a sorted list of prior purchases, and where a single purchase comprises sub-products from multiple co-located vending machines. Embodiments include the customer selecting either products or vending machines from a list of options provided via the user interface of the personal electronic device, wherein the list of options depends on the actual available inventory in vending machines co-located with the customer, and the customer purchase history.

Abstract: A system and method for vending products to a customer that encompasses a group of vending machines managed by a vending company, a database of the inventory of products in the vending machines and information about customer purchase history from the vending machines; and the use of a personal electronic device by the customer. Embodiments include the customer selecting either products or vending machines from a list of options provided via the user interface of the personal electronic device, wherein the list of options depends on the actual available inventory on vending machines co-located with customer, and the customer purchase history. Methods are described to permit advance purchases with deferred dispensing, and methods of payment that are both fast and automatic. Also described are methods of identifying vending machines and ordering a group of products as single request.

Abstract: Techniques are provided for calculating vending machines' service priorities and scheduling the vending machines for service taking into account a number of factors and thresholds (520). In some embodiments, the machines (110) are subdivided into subroutes (320). Each subroute has one or more machines, and at least one subroute has a plurality of machines. The vending machine service schedule is generated by selecting the highest priority subroute (410) and selecting the machines in that subroute (420). Other subroutes can be selected (430, 440) if there is time left in the Service Period.

Abstract: Techniques are provided for calculating vending machines' service priorities and scheduling the vending machines for service taking into account a number of factors and thresholds (520). In some embodiments, the machines (110) are subdivided into subroutes (320). Each subroute has one or more machines, and at least one subroute has a plurality of machines. The vending machine service schedule is generated by selecting the highest priority subroute (410) and selecting the machines in that subroute (420). Other subroutes can be selected (430, 440) if there is time left in the Service Period.

Abstract: An apparatus to interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The apparatus includes a base unit having illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. The system and apparatus may also include a tube for maintaining the distance between the tissue and units and for surrounding the tissue to prevent patient movement from being transmitted to the tissue.

Abstract: An apparatus to interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The apparatus includes a base unit having illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. The system and apparatus may also include a tube for maintaining the distance between the tissue and units and for surrounding the tissue to prevent patient movement from being transmitted to the tissue.

Abstract: Techniques are provided for calculating vending machines' service priorities and scheduling the vending machines for service taking into account a number of factors and thresholds (520). In some embodiments, the machines (110) are subdivided into subroutes (320). Each subroute has one or more machines, and at least one subroute has a plurality of machines. The vending machine service schedule is generated by selecting the highest priority subroute (410) and selecting the machines in that subroute (420). Other subroutes can be selected (430, 440) if there is time left in the Service Period.

Abstract: Techniques are provided for calculating vending machines' service priorities and scheduling the vending machines for service taking into account a number of factors and thresholds (520). In some embodiments, the machines (110) are subdivided into subroutes (320). Each subroute has one or more machines, and at least one subroute has a plurality of machines. The vending machine service schedule is generated by selecting the highest priority subroute (410) and selecting the machines in that subroute (420). Other subroutes can be selected (430, 440) if there is time left in the Service Period.

Abstract: Systems and methods for remotely managing a vending machine system are provided. A host system transmits control data to an audit system installed in a vending machine system. This control data is used to modify a data collection parameter of the audit system, such as modifying alert conditions, reporting schedules, and filter terms used to parse DEX files received from a vending machine controller.

Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.