Patents by Inventor Anat Frydman-Marom

Anat Frydman-Marom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dipeptide analogs for treating conditions associated with amyloid fibril formation
    Patent number: 9630989
    Abstract: Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The dipeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the dipetide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: April 25, 2017
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud Gazit, Yaniv Amir, Ludmila Buzhansky, Ulrich Abel, Anat Frydman-Marom
  • DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION
    Publication number: 20150322110
    Abstract: Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The dipeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the dipetide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.
    Type: Application
    Filed: July 22, 2015
    Publication date: November 12, 2015
    Applicant: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud GAZIT, Yaniv Amir, Ludmila Buzhansky, Ulrich Abel, Anat Frydman-Marom
  • Dipeptide analogs for treating conditions associated with amyloid fibril formation
    Patent number: 9096645
    Abstract: Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The dipeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the dipeptide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.
    Type: Grant
    Filed: November 15, 2011
    Date of Patent: August 4, 2015
    Assignee: Ramot at Tel-Aviv University Ltd.
    Inventors: Ehud Gazit, Yaniv Amir, Ludmila Buzhansky, Ulrich Abel, Anat Frydman-Marom
  • DIPEPTIDE ANALOGS FOR TREATING CONDITIONS ASSOCIATED WITH AMYLOID FIBRIL FORMATION
    Publication number: 20130225512
    Abstract: Dipeptide analogs comprising a tryptophan (Trp) moiety coupled to a beta-sheet breaker moiety derived from alpha-aminoisobutyric acid (Aib) are disclosed. The dipeptide analogs exhibit an improved performance in inhibiting amyloid fibril formation, as compared to previously described dipeptides. Compositions containing the dipeptide analogs and uses thereof in treating amyloid-associated diseases and disorders are also disclosed.
    Type: Application
    Filed: November 15, 2011
    Publication date: August 29, 2013
    Applicant: Merz Pharma GmbH & Co. KGaA
    Inventors: Ehud Gazit, Yaniv Amir, Ludmila Buzhansky, Ulrich Abel, Anat Frydman-Marom
  • USE OF A CINNAMON BARK EXTRACT FOR TREATING AMYLOID-ASSOCIATED DISEASES
    Publication number: 20110200692
    Abstract: The present application disclosed the use of a cinnamon extract in the treatment of amyloid-associated diseases and disorders, such as Alzheimer's disease.
    Type: Application
    Filed: October 11, 2009
    Publication date: August 18, 2011
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventors: Michael Ovadia, Ehud Gazit, Anat Frydman-Marom