Abstract: The inventive device for enclosing histological and biological samples comprises a platform for an object glass and means for placing a cover glass thereto. Said means for placing the cover glass is embodied in the form of a comb arranged above the platform and provided with a mechanism for a pendulous (the first embodiment of the device) or reciprocating (the second embodiment of the device) motion above said platform. The platform is limited by a vertical arrest which is arranged on the side of the means for placing a cover glass and provided with slots for accommodating the comb teeth therein. In addition, said device can be provided with a rolling press arranged above the comb.