Abstract: The invention relates to an absorbent adhesive body of a foamed pressure sensitive hydrocolloid adhesive comprising one or more water soluble or water swellable hydrocolloids and having gas bubbles incorporated therein, where the gas in the gas bubbles are in direct contact with the pressure sensitive hydrocolloid adhesive and where tan ? for the adhesive in un-foamed form is below 0.35 at 40° C. and 0.001 rad/sec.

Abstract: The current invention relates to radially divided adhesive wafers for applying to the skin of a human, and which increases the wear time of such adhesive wafers. More specifically, detailed embodiments relating to radially divided adhesive wafers for use in ostomy appliances are described. This is done by providing an adhesive wafer comprising a through-going hole for communication with a body opening and an adhesive proximal side for attachment of the wafer to the skin surrounding the body opening.

Abstract: Accordingly, the present invention relates to a pressure sensitive adhesive composition consisting of a continuous phase comprising cross-linked polyalkyleneoxide polymer and a discontinuous phase comprising water absorbent hydrophilic agents wherein a) the water absorbent hydrophilic agent(s) is present in an amount between 1 and 40% w/w of the total adhesive composition; and b) the continuous phase comprises the reaction product (X) of: (i) a polyalkyleneoxide polymer having one or more unsaturated end groups, and where more than 90% w/w of the polyalkylene oxide polymer consist of polymerised alkyleneoxide moities having three or more carbon atoms, and (ii) an organosiloxane comprising one or more Si—H groups, carried out in the presence of an addition reaction catalyst. The present invention also relates to medical devices comprising such pressure sensitive adhesives.

Abstract: A body waste collecting device comprising a collecting pouch and an adhesive wafer for attachment to the body, said adhesive wafer comprising a backing layer, at least one intermediate layer of adhesive, a skin facing layer of adhesive and a film layer, said intermediate layer of adhesive and said skin facing layer of adhesive comprise liquid impermeable, moisture permeable soft adhesives and said film layer is positioned between said skin facing layer of adhesive and said intermediate layer of adhesive.

Abstract: The present invention is directed to the provision of small molecule inhibitors of the PSD-95/NMDA receptor interaction, employing an undecapeptide corresponding to the C-terminal of the NMDA as a template for finding lead candidates. A compound (NMDAR/PSD-95 inhibitor) of the invention includes a peptide or peptide analogue comprising at least four peptide bonded residues having the sequence YTXV or YSXV, wherein Y is selected from among E, Q, and A, or an analogue thereof and X is selected from among A, Q, D, N, N-Me-A, N-Me-Q, N-Me-D, and N-Me-N or an analogue thereof, wherein an amino-terminal residue of the peptide is N-alkylated.

Abstract: An ostomy collecting device for attachment to the body comprising a collecting pouch and an adhesive wafer, the wafer comprises a soft adhesive layer and a backing layer wherein the wafer is more stretchable in a first direction than in a second direction. The anisotropic nature of the wafer facilitates a flexible wafer during use and secures easy removal.

Abstract: A body waste collecting device comprising a collecting pouch and an adhesive wafer for attachment to the body, said adhesive wafer comprises a backing layer, a first adhesive and an additional second adhesive, wherein said additional second adhesive comprises a polar plasticising oil or a combination of polar plasticising oils in the content of above 10% (w/w) of the final second adhesive, and at least one polar polyethylene copolymer, wherein the content of the polyethylene copolymer is 10-50% (w/w) of the final second adhesive, the polyethylene copolymer has a melt flow index below 2 g/10 min (190° C./21.1 N).

Abstract: A layered adhesive construction including a layer of a moldable paste wrapped in one or more wrapping layers, and a first adhesive layer attached to the wrapping layer on one outer surface of the layer of wrapped moldable paste where the layered adhesive construction has a symmetrical shape around a central axis of symmetry lying in the plane of the layers of the adhesive construction. The adhesive construction has a hole going therethrough which is placed with its center on the axis of symmetry so that it divides the central axis of symmetry in two parts. An area around at least one of the two parts on the central axis of symmetry is without the moldable paste layer and has one or more backing layers and a layer of adhesive on the same side of the adhesive construction as the first adhesive layer.

Abstract: The present invention relates to a pressure sensitive adhesive composition comprising a continuous phase and a discontinuous phase wherein a) the continuous phase comprises a water vapour permeable hydrophobic polymer; and b) the discontinuous phase comprises a water soluble compound.

Abstract: An ostomy appliance for attachment to the stoma body comprising a soft adhesive wafer (1) having a tensile strength at 20% strain of less than 0.75N/4 mm and a collecting pouch attachable to an adhesive wafer, the wafer comprises a backing layer and a skin-facing adhesive layer, wherein the adhesive skin-facing surface of the wafer is provided with at least two release liners (3, 4) each covering at least a part of the adhesive surface and together covering the entire adhesive surface.

Abstract: A body waste collecting device comprising a collecting pouch and an adhesive wafer for attachment to the body, said adhesive wafer comprising a backing layer and a first adhesive layer, said first adhesive layer comprising a liquid impermeable, moisture permeable adhesive composition wherein the adhesive wafer comprising an additional second adhesive for sealing around a body opening.

Abstract: A body waste collecting device for attachment to the body comprising a collecting pouch comprising a first wall and a second wall, the pouch being attached to an adhesive wafer, wherein a central portion of the wafer constitutes a part of the first wall of the pouch, the wafer comprises a permeable backing layer, at least one layer of an absorbent adhesive layer wherein the wafer comprises a moisture impermeable layer at least in the central portion.

Abstract: A component for sealing a body opening and for use in combination with a body waste collecting device, said component comprises a soft adhesive composition wherein the soft adhesive composition comprises a liquid impermeable, moisture permeable adhesive composition.

Abstract: A body waste collecting device comprising an adhesive composite that fastens a collecting bag to the skin is disclosed. The adhesive composite is highly moisture resistant while still being water absorbing. The adhesive composite comprises at least three layers, a backing layer, a moisture absorbing layer and a thin layer of vapour permeable, low-absorbing adhesive layer.

Abstract: A collecting device comprising a collecting pouch and an adhesive wafer for attachment to the body, said wafer comprising at least one low-modulus backing layer and an elastic adhesive gel layer comprising a polyalkyleneoxide polymer and an organosiloxane based cross-linked adhesive system.

Abstract: The present invention relates to a pressure sensitive adhesive composition comprising a continuous phase and a discontinuous phase wherein a) the continuous phase comprises a water vapour permeable hydrophobic polymer; and b) the discontinuous phase comprises a water soluble salt.

Abstract: Accordingly, the present invention relates to a pressure sensitive adhesive composition consisting of a continuous phase comprising cross-linked polyalkyleneoxide polymer and a discontinuous phase comprising water absorbent hydrophilic agents wherein a) the water absorbent hydrophilic agent(s) is present in an amount between 1 and 40% w/w of the total adhesive composition; and b) the continuous phase comprises the reaction product (X) of: (i) a polyalkyleneoxide polymer having one or more unsaturated end groups, and where more than 90% w/w of the polyalkylene oxide polymer consist of polymerised alkyleneoxide moities having three or more carbon atoms, and (ii) an organosiloxane comprising one or more Si—H groups, carried out in the presence of an addition reaction catalyst. The present invention also relates to medical devices comprising such pressure sensitive adhesives.

Abstract: A kit for collecting stool, comprising an adapter (1) for connecting the anus or a perianal stoma of a user to a peripheral device, said adapter comprises a flexible adhesive plate (2) having first through going hole, a flexible tube (3) extending from a first opening (11) to a second opening (12) and a first flexible coupling plate (4) having a second through going hole, wherein the flexible tube is attached to the flexible adhesive plate in an area surrounding the first opening and the flexible tube is attached to the first flexible coupling plate in an area encircling the second opening, allowing fluid communication from the first through going hole to the second through going hole through the flexible tube, and a peripheral device (20, 60) for coupling to the adapter.

Abstract: A layered adhesive construction comprising a layer of a mouldable paste wrapped in one or more wrapping layers, and comprising a first adhesive layer attached to the wrapping layer on one outer surface of said layer of wrapped mouldable paste where the layered adhesive construction has a symmetrical shape around a central axis of symmetry lying in the plane of the layers of the adhesive construction, and has a hole going through the adhesive construction, which hole is placed with its center on said axis of symmetry so that it divides the central axis of symmetry in two parts; and where an area around at least one of said two parts of the central axis of symmetry consist of one or more backing layers and a layer of adhesive on the same side of the adhesive construction as the first adhesive layer.

Abstract: The invention relates to an absorbent adhesive body of a foamed pressure sensitive hydrocolloid adhesive comprising one or more water soluble or water swellable hydrocolloids and having gas bubbles incorporated therein, where the gas in the gas bubbles are in direct contact with said pressure sensitive hydrocolloid adhesive and where tan ? for said adhesive in un-foamed form is below 0.35 at 40° C. and 0.001 rad/sec.