Patents by Inventor Anders Brunmark

Anders Brunmark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders
    Patent number: 7795440
    Abstract: The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: September 14, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Chih Yung Ho, Bengt Anders Brunmark, Stuart Emanuel, Robert A. Galemmo, Jr., Dana L. Johnson, Donald W. Ludovici, Umar Maharoof, Jay M. Mei, Jan L. Sechler, Eric D. Strobel, Robert W. Tuman, Hwa Kwo Yen
  • N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders
    Patent number: 7196110
    Abstract: The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: March 27, 2007
    Assignee: Janssen Phamaceutica N.V.
    Inventors: Chih Yung Ho, Bengt Anders Brunmark, Stuart Emanuel, Robert A. Galemmo, Jr., Dana L. Johnson, Donald W. Ludovici, Umar Maharoof, Jay M. Mei, Jan L. Sechler, Eric D. Strobel, Robert W. Tuman, Hwa Kwo Yen
  • Antigen presenting system and methods for activation of T-cells
    Publication number: 20050152916
    Abstract: The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8+ T-cells to produce cytokines and become cytotoxic.
    Type: Application
    Filed: December 7, 2004
    Publication date: July 14, 2005
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per Peterson, Alain Luxembourg, Didier Leturcq, Ann Moriarty
  • Antigen presenting system and methods for activation of T-cells
    Patent number: 6828150
    Abstract: The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8+ T-cells to produce cytokines and become cytotoxic.
    Type: Grant
    Filed: October 8, 2002
    Date of Patent: December 7, 2004
    Assignee: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson, Alain Luxembourg, Didier J. Leturcq, Ann M. Moriarty
  • N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders
    Publication number: 20040082639
    Abstract: The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
    Type: Application
    Filed: May 14, 2003
    Publication date: April 29, 2004
    Inventors: Chih Yung Ho, Bengt Anders Brunmark, Stuart Emanuel, Robert A. Galemmo, Dana L. Johnson, Donald W. Ludovici, Umar Maharoof, Jay M. Mei, Jan L. Sechler, Eric D. Strobel, Robert W. Tuman, Hwa Kwo Yen
  • Antigen presenting system and methods for activation of T-cells
    Publication number: 20030138946
    Abstract: The present invention relates to synthetic antigen-presenting matrices, their methods of making and their methods of use. One such matrix is cells that have been transfected to produce MHC antigen-presenting molecules and assisting molecules such as co-stimulatory molecules. The matrices can be used to activate CD8+ T-cells to produce cytokines and become cytotoxic.
    Type: Application
    Filed: October 8, 2002
    Publication date: July 24, 2003
    Applicant: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson, Alain Luxembourg, Didier J. Leturcq, Ann M. Moriarty
  • Synthetic antigen presenting matrix
    Publication number: 20030077318
    Abstract: Materials and methods for activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting cell line for activating T lymphocytes to a specific peptide is described.
    Type: Application
    Filed: March 25, 2002
    Publication date: April 24, 2003
    Applicant: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson
  • Antigen presenting system and methods for activation of T-cells
    Publication number: 20030077708
    Abstract: Materials and methods for activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting cell line for activating T lymphocytes to a specific peptide is described.
    Type: Application
    Filed: March 25, 2002
    Publication date: April 24, 2003
    Applicant: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson
  • Synthetic antigen presenting matrix with liposome support
    Publication number: 20030072796
    Abstract: Materials and methods for activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting cell line for activating T lymphocytes to a specific peptide is described.
    Type: Application
    Filed: March 25, 2002
    Publication date: April 17, 2003
    Applicant: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson
  • Synthetic antigen presenting matrix
    Patent number: 6461867
    Abstract: Materials and methods of activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a synthetic antigen presenting matrix for activating T lymphocytes to a specific peptide is described.
    Type: Grant
    Filed: September 8, 1997
    Date of Patent: October 8, 2002
    Assignee: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson, Alain Luxembourg, Didier J. Leturcq, Ann M. Moriarty
  • Method for producing a synthetic antigen presenting transformed Drosophila cell
    Patent number: 6362001
    Abstract: Materials and methods of activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, a method for producing a synthetic antigen presenting drosophila cell line for activating T lymphocytes to a specific peptide is described.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: March 26, 2002
    Assignee: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson
  • Antigen presenting system and methods for activation of T-cells
    Patent number: 6255073
    Abstract: Materials and methods of activating T lymphocytes with specificity for particular antigenic peptides are described, as well as the use of activated T lymphocytes in vitro for the treatment of a variety of disease conditions. In particular, fragments of cells for activating T lymphocytes to a specific peptide are described.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: July 3, 2001
    Assignee: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson
  • Antigen presenting system and methods for activation of T-cells
    Patent number: 6251627
    Abstract: The present invention relates to methods for producing synthetic matrix for activating T lymphocytes.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: June 26, 2001
    Assignee: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson
  • Antigen presenting system and methods for activation of T-cells
    Patent number: 6225042
    Abstract: The present invention relates to methods for activating T lymphocytes using a synthetic matrix, and for specifically activating T lymphocytes reactive to a specific peptide.
    Type: Grant
    Filed: March 16, 1998
    Date of Patent: May 1, 2001
    Assignee: The Scripps Research Institute
    Inventors: Zeling Cai, Jonathan Sprent, Anders Brunmark, Michael Jackson, Per A. Peterson