Abstract: The invention relates to an injection device comprising a housing, a container holder arranged within said housing, the container holder being configured for accommodating a medicament container having a needle attached to one end thereof and a stopper sealingly and slidable arranged inside the medicament container at the other end thereof, a drive unit comprising a plunger rod and plunger drive means, the plunger drive means being slidable arranged in relation to the plunger rod, being rotationally locked to the plunger rod and being rotatable in relation to the housing, said drive unit further comprising a first energy accumulating member arranged in the interior of the housing of the injection device and adapted to accumulate and store energy, wherein said plunger drive means is operationally associated with said first energy accumulating member, wherein the plunger drive means is releasable such that due to an output torque from said first energy accumulating member, the plunger drive means are allowed to

Abstract: The present invention relates to a medicament delivery device comprising a housing (10,12), capable of containing a medicament container (14), a plunger rod (18) and a drive member (34) arranged to said plunger rod and capable of acting on said plunger rod (18) for moving it in the proximal direction of the device for expelling a dose of medicament from said medicament container (14), a dose and drive setting mechanism (52) comprising a dose setting member (56) operably connected to a force member (82) such that setting of a dose causes said force member (82) to be energized. The intermediate member (68) is configured to interact with a dose setting sleeve (50) through a first unidirectional connection (64, 62), configured to interact with said drive member (34) through a second unidirectional connection (70, 72), and configured to interact with a dose drive sleeve (76) through a third connection (74,78).

Abstract: A combination product including at least one filler product and at least at least one bioresorbable and biodegradable silica-based material, for treating incontinence or treating aging of the skin and scars. Also, a composition including, in a physiologically acceptable medium, at least one filler product and at least at least one bioresorbable and biodegradable silica-based material.

Abstract: The present invention relates to a device for the delivery of predetermined doses of liquid medicament to a patient, which medicament is intended to be inhaled by the patient or intended to be injected into the body of the patient. The device is adapted to be in a medicament delivery state and in a medicament non-delivery state. When the device is in a medicament delivery state, said device is adapted to drive a piston into a cartridge containing the liquid medicament to be delivered, with a force that is above or equal to a predetermined minimum force value and below a predetermined maximum force value. The minimum force value is the lowest force value needed to deliver the predetermined dose and the maximum force value is the first force value at which it exists a risk of damaging the cartridge or the components of the device. Further, more of the spring force is brought to an efficient output torque ensuring that a predetermined volume of medicament is expelled from a cartridge.

Abstract: The present invention relates to an industrial fabric, in particular press fabric or transfer belt, for use in a papermaking machine. The industrial fabric includes a porous composite structure, having a batt fiber structure and particulate polymeric material. The batt fiber structure has an upper surface and a lower surface extending parallel to the upper surface and spaced from the upper surface along a thickness direction extending perpendicular to the upper and lower surface. The particulate polymeric material is partly fused together and bonded with fibers extending on at least one of the surfaces of the batt fiber structure and with fibers inside the batt fiber structure such that the polymeric material partly impregnates fibers of the batt structure and partly fills interstices between fibers of the batt structure to form the porous composite structure.

Abstract: A medicament delivery device has a housing for a medicament container and a drive unit for a stopper in the container to expel a dose of medicament, the drive unit having a plunger rod and a dual back-to-back force spring assembly connected to the plunger rod; and a lock and release mechanism connected to the drive unit that has a hold member, and a tubular actuation member linearly slidable in relation to the housing and connected to the rotator member. The hold member is attached to the housing and has a generally tubular lock tube through which the plunger rod extends and two half-cylindrical seats for the dual back-to-back force spring assembly. The lock tube has a resilient lock and release device to interact with both the plunger rod and the rotator member.

Abstract: The present invention relates to a device for expelling a predetermined quantity of medicament comprising driving means comprising an energy-accumulating member, a nut, and a driver for driving a pressure means; and activation means for activating said driving means wherein said pressure means comprises a movable wall part arranged inside a 2 container and a threaded plunger rod arranged to interact with said driving means for pushing said movable wall part forwardly, and wherein said activation means comprises a manually operated push button arranged on the front end of the device for promoting an ergonomic handling of the device and wherein said activation means are capable of interacting with said driving means in a stepwise mode; such that each time said push button is depressed said pressure means moves an step exerting pressure on the medicament inside the container and expelling a predetermined quantity of the medicament through the opening.

Abstract: A mixing device for a fuel reformer for mixing at least two fluids is provided. The mixing device includes at least a first plurality of holes which is arranged along a first row, and a second plurality of holes which is arranged along a second row. The mixing device can be used in a fuel reformer for converting hydrocarbon fuel into hydrogen rich gas by auto-thermal reaction process having a, preferably cylindrically shaped and double walled, housing with two side walls forming a reaction chamber of the fuel reformer, wherein hydrocarbon fuel and an oxidizing agent are mixed by the mixing device.

Abstract: A device and method for controlling the rapping of at least one collecting electrode plate (30) of an electrostatic precipitator (1) is provided. The device controls such rapping by applying, by means of a power source (32), a voltage between at least one collecting electrode plate (30) and at least one discharge electrode (28). The sparking rate between the at least one collecting electrode plate (30) and at least one discharge electrode (28) is then measured, with the rapping of the at least one collecting electrode plate (30) controlled using the measured present sparking rate.

Abstract: A method and a system for controlling dust particle emissions from an electrostatic precipitator (1), which has a first and a second bus-section (16, 20), are provided. Dust particle emissions are controlled by observing that a rapping event of the first bus-section (16) is about to be initiated, verifying, before allowing the rapping event of the first bus-section (16) to be initiated, that the second bus-section (20) is ready to receive the dust particles to be released during the rapping event of the first bus-section (16), and then initiating, after verification, the rapping event of the first bus-section (16).

Abstract: The present invention describes oligosaccharide sequences, which are specifically expressed by human tumors. The present invention is related to a method of determining an oligosaccharide sequence, which comprises a tumor specific terminal N-acetylglucosamine residue, in a biological sample, the presence of said sequence in said sample being an indication of the presence of cancer. The present invention provides antigenic substances comprising said oligosaccharide sequences in a polyvalent form and it further provides diagnostic agents, pharmaceutical compositions and cancer vaccines comprising said oligosaccharide sequences or substances binding to said oligosaccharide sequences. The present invention is also related to methods for the treatment of cancer.

Abstract: Embodiments of the invention relate to a method and a checkweigher for weighing individual products moved along a production line. In various embodiments, the method compromises transferring at least one product from the production line to a checkweigher comprising at least one weighing cell; placing at least one product in a first position on a first support above a corresponding weighing cell; displacing the at least one product by means of said first support and placing said at least one product in a second position on a second support on the weighing cell; weighing the at least one product; displacing the at least one product back to the first position by means of said first support; and transferring the at least one product from the checkweigher back to the production line.

Abstract: The present invention relates to a device for delivering medicament, comprising a container (12) arranged to contain medicament, which container further comprises an opening arranged to expel medicament from the container, pressure means (16, 18) arranged to exert pressure on the medicament inside the container (12) for expelling a certain predetermined quantity of the medicament through the opening, driving means (26, 42) for driving said pressure means (16, 18), and activation means (46) for activating said driving means (26, 42) wherein said device comprises pressure release means (20) which are adapted, arranged and designed such that, when the predetermined dose has been expelled through the opening, the pressure on the medicament is released.

Abstract: A reformer reactor is provided for converting hydrocarbon fuel into hydrogen rich gas by auto-thermal reaction process having a cylindrically shaped and double walled, housing with two side faces forming a reaction chamber of the reformer. Additionally, a fuel inlet is provided in one of the two side faces for providing hydrocarbon fuels into the reaction chamber, wherein further a fuel preheating means is provided which preheats the hydrocarbon fuel before the hydrocarbon fuel enters the reaction chamber.

Abstract: The present invention relates to sealing means made of a plastically deformable material for mechanical sealing of hollow hoses (2) of elastic material by means of an appliance having at least two jaws, at least one of which is movable towards and away from the other and which, when moving towards each other, crimp the sealing means against the hose (2) for contamination-tight sealing of the same, the sealing means (20) comprises at least one sealing member (4, 4?; 44, 44?; 64, 64?; 74, 74?; 84), which has two opposite ends and an opening (40, 40?) that extends between said ends to allow the at least one sealing member to be slipped onto the hose (2) to be sealed. The present invention also relates to a kit comprising a sealing means and an appliance for sealing of hollow hoses and to a method for mechanical sealing of hollow hoses.

Abstract: The present invention relates to sealing means made of a plastically deformable material for mechanical sealing of hollow hoses (2) of elastic material by means of an appliance having at least two jaws, at least one of which is movable towards and away from the other and which, when moving towards each other, crimp the sealing means against the hose (2) for contamination-tight sealing of the same, the sealing means (20) comprises at least one sealing member (4, 4?; 44, 44?; 64, 64?; 74, 74?; 84), which has two opposite ends and an opening (40, 40?) that extends between said ends to allow the at least one sealing member to be slipped onto the hose (2) to be sealed. The present invention also relates to a kit comprising a sealing means and an appliance for sealing of hollow hoses and to a method for mechanical sealing of hollow hoses.

Abstract: The instant invention provides plasma membrane vesicles, methods of making the same, and method of using the plasma membrane vesicles.

Abstract: Disclosed herein is a device comprising at least one supporting solid surface comprising at least one membraneophilic region; a covering layer that is at least partially immobilized to the membraneophilic region, said covering layer consisting of (i) a surfactant membrane, (ii) a lipid mimicking polymer, (iii) a surfactant or emulsion system or (iv) a liquid crystal; and a substance included in or bound to, connected to or associated with the covering layer. Also disclosed are methods wherein the device is used and use of the device.

Abstract: The present invention is directed to human influenza virus binding substance containing at least one oligosaccharide chain, which comprises a terminal NeuNAc?6 linked to: (a) a linear or branched polylactosamine type structure consisting of at least three lactosamine residues, a linear sequence optionally containing one or two ?3-linked fucose residues in a non-sialylated lactosamine, a branched structure optionally carrying one or more additional NeuNAc?-residues at a terminal position in a branch, and/or (b) a linear or branched structure with two lactosamine and one lactose residue, a linear structure in addition containing one or two ?3-linked fucose residues in a non-sialylated lactosamine or lactose, a branched structure optionally carrying one additional NeuNAc?-residue in a terminal position of the branch, or an analog or derivative of said oligosaccharide chain for use in binding of human influenza virus.

Abstract: The present invention relates to a method of making cutting tools comprising a substrate having a hard phase and a binder phase, the method comprising forming green powder compacts using powder metallurgical techniques, charging the green powder compacts, placed on one or several trays, in a furnace and sintering the green powder compacts wherein the furnace comprises an insulation package, at least three individually controlled heating elements located inside the insulation package including a vertical heating element, an upper horizontal heating element arranged in an upper part of the furnace, and a lower horizontal heating element arranged in a lower part of the furnace, wherein operating the at least three heating elements such that an average controlled cooling rate from a sintering temperature down to at least a solidification temperature of the binder phase is 0.1-4.0° C./min, and a sintering furnace operable to obtain a controlled cooling rate.