Patents by Inventor Anders Laerke Nielsen

Anders Laerke Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FVIIa-sTF complexes exhibiting exosite-mediated super activity
    Publication number: 20150044195
    Abstract: Disclosed are disulphide-linked complexes of a soluble Tissue Factor (sTF) variant of SEQ ID NO:3 comprising the mutation G109C and a Factor VIIa variant of SEQ ID NO. 1, comprising the mutation Q64C and a mutation at position M306 that gives rise to a zymogen-like conformation in the Factor VIIa polypeptide. Said complexes may be used for the treatment of a coagulopathy.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 12, 2015
    Applicant: NOVO NORDISK HEALTHCARE AG
    Inventors: Henrik Oestergaard, Anders Laerke Nielsen, Ole Hvilsted Olsen
  • Process for the Purification of Antibodies Using Affinity Resins Comprising Specific Ligands
    Publication number: 20110319592
    Abstract: The present invention relates to a novel process for the purification of antibodies, e.g. monoclonal antibodies. The process utilizes an affinity resin comprising a solid phase material having immobilized thereto one or more low-molecular weight synthetic ligands. The affinity resins enable the separation of antibodies from even closely related proteins.
    Type: Application
    Filed: November 13, 2009
    Publication date: December 29, 2011
    Applicant: Novo Nordisk A/S
    Inventors: Phaedria Marie St. Hilaire, Anders Laerke Nielsen